個(gè)人簡(jiǎn)介
清華信息科學(xué)與技術(shù)國(guó)家實(shí)驗(yàn)室(籌)生物信息學(xué)部
生物信息學(xué)教育部重點(diǎn)實(shí)驗(yàn)室
履歷
教育背景
1999.9 - 2003.7 清華大學(xué)自動(dòng)化系自動(dòng)化專(zhuān)業(yè),獲工學(xué)學(xué)士學(xué)位
2003.9 - 2008.7 清華大學(xué)自動(dòng)化系控制科學(xué)與工程-生物信息學(xué)專(zhuān)業(yè), 獲博士學(xué)位
2007.9 - 2008.3 美國(guó)冷泉港實(shí)驗(yàn)室,國(guó)家公派聯(lián)合培養(yǎng)博士生
工作履歷
2008.7 - 2011.11清華大學(xué)自動(dòng)化系,講師
2011.12 至今,清華大學(xué)自動(dòng)化系 副教授
學(xué)術(shù)兼職
國(guó)家自然科學(xué)基金評(píng)審人
擔(dān)任Bioinformatics、BMC Bioinformatics、PLoS One、Chromatin、Epigenetics、The Annals of Applied Statistics、APBC2009、APBC2010、《科學(xué)通報(bào)》、《遺傳學(xué)報(bào)》等國(guó)內(nèi)外期刊和會(huì)議的審稿人
研究領(lǐng)域
生物信息學(xué)
· 微小RNA(microRNA)的計(jì)算系統(tǒng)生物學(xué)研究
· 基因表達(dá)調(diào)控網(wǎng)絡(luò)分析
·表觀遺傳學(xué)研究
·高通量測(cè)序數(shù)據(jù)的分析與算法開(kāi)發(fā)
合成生物學(xué)
· 基于系統(tǒng)生物學(xué)的人工生命系統(tǒng)的建模與仿真
· 人工生命系統(tǒng)的設(shè)計(jì)理論與方法
獎(jiǎng)勵(lì)與榮譽(yù)
2010年全國(guó)優(yōu)秀博士學(xué)位論文
2009年國(guó)家教學(xué)成果二等獎(jiǎng)(張學(xué)工、李梢、李衍達(dá)、江瑞、汪小我)
2008年北京市教學(xué)成果一等獎(jiǎng)(張學(xué)工、李梢、李衍達(dá)、江瑞、汪小我)
學(xué)術(shù)成果
· 王曦, 汪小我, 王立坤, 馮智星, 張學(xué)工, 新一代高通量RNA測(cè)序數(shù)據(jù)的處理與分析, 生物化學(xué)與生物物理進(jìn)展, 37(8):834-846, 2010
· Agustin Chicas, Xiaowo Wang, Chaolin Zhang, Mila McCurrach, Zhen Zhao, Ozlem Mert, Ross A. Dickins, Masashi Narita, Michael Zhang and Scott W. Lowe, Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence, Cancer Cell, 17(4): 376-387, 2010
· Tingting Li, Xueya Zhou, Xiaowo Wang, Dahai Zhu, Yong Zhang, Identification and characterization of human snoRNA core promoters, Genomics, 96(1):50-6, 2010
· Likun Wang, Zhixing Feng, Xi Wang, Xiaowo Wang*, Xuegong Zhang*, DEGseq: an R package for identifying differentially expressed genes from RNA-seq data, Bioinformatics, 26(1):136-138 2010 (*co-corresponding Author)
· Xiaowo Wang, Zhenyu Xuan, Xiaoyue Zhao, Yanda Li, Michael Q. Zhang, High-resolution human core-promoter prediction with CoreBoost_HM, Genome Research, 19(2):266-75, 2009
· Xiaowo Wang , Jin Gu, Michael Q. Zhang and Yanda Li., Identification of phylogenetically conserved microRNA cis-regulatory elements across 12 Drosophila species, Bioinformatics, 15;24(2):165-71,2008
· Tao Peng, Chenghai Xue, Jianning Bi, Tingting Li, Xiaowo Wang, Xuegong Zhang and Yanda Li, Functional importance of different patterns of correlation between adjacent cassette exons in human and mouse, BMC Genomics, 26;9:191, 2008
· Xiaowo Wang , Xuegong Zhang, Yanda Li, Complicated evolutionary patterns of miRNAs in vertebrates, Sci China Ser C-Life Sci, 51(6):552-9 2008
· 汪小我,張學(xué)工,李衍達(dá),脊椎動(dòng)物中微小RNA進(jìn)化模式研究, 中國(guó)科學(xué)C輯:生命科學(xué),2008, 38(4):348-355
· Jian Huang, Pei Hao, Yun-Li Zhang, Fu-Xing Deng, Qing Deng, Yi Hong, Xiaowo Wang, Yun Wang, Ting-Ting Li, Xue-Gong Zhang, Yi-Xue Li, Peng-Yuan Yang, Hong-Yang Wang and Ze-Guang Han. Discovering multiple transcripts of human hepatocytes using massively parallel signature sequencing (MPSS), BMC Genomics, 8:207,2007
· Jin Gu, Tao He, Yunfei Pei, Fei Li, Xiaowo Wang, Jing Zhang, Xuegong Zhang and Yanda Li, Primary Transcripts and Expressions of Mammal Intergenic MicroRNAs Detected by Mapping ESTs to Their Flanking Sequences. Mamm Genome, 17(10):1033-1041, 2007
· Xiaowo Wang, Jing Zhang, Fei Li , Jin Gu , Tao He , Xuegong Zhang and Yanda Li, MicroRNA identification based on sequence and structure alignment. Bioinformatics, 21 (18): 3610-4, 2005