人物經(jīng)歷
2000.9-2004.6北京大學(xué)化學(xué)與分子工程學(xué)院,理學(xué)學(xué)士,導(dǎo)師:楊震教授;
2004.7-2009.11 The Scripps Research Institute,California,USA,Ph.D.,導(dǎo)師:Prof. K. C. Nicolaou;
2010.1-2010.9 Institute of Chemical and Engineering Sciences,Singapore,research fellow,導(dǎo)師:Prof. K. C. Nicolaou;
2010.9-至今中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所,“百人計(jì)劃”研究員
研究方向
復(fù)雜的多環(huán)及籠狀天然產(chǎn)物的全合成;基于分子結(jié)構(gòu)對(duì)稱(chēng)性和生物合成路徑的高效合成策略的發(fā)展;具有重要生理活性的生物堿的合成策略和方法的研究;新穎的生物正交反應(yīng)(bioorthogonal reaction)及其在化學(xué)生物學(xué)中的應(yīng)用。
代表論著
1.M. Bian, Z. Wang, X. C. Xiong, Y. Sun, C. Matera, K. C. Nicolaou,* and A. Li,* Total Syntheses of Anominine and Tubingensin A, J. Am. Chem. Soc. 2012, 134, Articles ASAP
2.J. Deng, B. Zhu, Z. Lu, H. Yu, A. Li,* Total Synthesis of (u2013)-Fusarisetin A and Reassignment of the Absolute Configuration of Its Natural Counterpart, J. Am. Chem. Soc
3.C.-C. Tseng, H. Ding, A. Li, Y. Guan, D. Y.-K. Chen, A Modular Synthesis of Salvileucalin B Structural Domains, Org. Lett.
4.K. C. Nicolaou, A. Li, D. J. Edmonds, G. S. Tria, S. P. Ellery, Total Syntheses of Platensimycin and Related Natural Products, J. Am. Chem. Soc
5.K. C. Nicolaou, A. Li, S. P. Ellery, D. J. Edmonds, Rhodium-Catalyzed Asymmetric Enyne Cycloisomerization of Terminal Alkynes and Formal Total Synthesis of (u2013)-Platensimycin, Angew. Chem. Int. Ed
6.K. C. Nicolaou, A. F. Stepan, T. Lister, A. Li, A. Montero, G. S. Tria, C. I. Turner, Y. Tang, J. Wang, R. M. Denton, D. J. Edmonds, Design, Synthesis and Biological Evaluation of Platensimycin Analogs with Varying Degrees of Molecular Complexity, J. Am. Chem. Soc
7.K. C. Nicolaou, A. Li, Total Syntheses and Structural Revision of α- and β-Diversonolic Esters and Total Syntheses of Diversonol and Blennolide C, Angew. Chem. Int. Ed.
8.K. C. Nicolaou, Y. Tang, J. Wang, A. F. Stepan, A. Li, A. Montero, Total Synthesis and Antibacterial Propoties of Carbaplatensimycin, J. Am. Chem. Soc.
9.K. C. Nicolaou, D. J. Edmonds, A. Li, G. S. Tria, Asymmetric Total Syntheses of Platensimycin, Angew. Chem. Int. Ed.
10.K. C. Nicolaou, A. Li, D. J. Edmonds, Total Synthesis of Platensimycin, Angew. Chem. Int. Ed. 2006, 45, 7086u20137090. (This work was highlighted by Nature 2006, 443, 726, Chemical and Engineering News
11.K. C. Nicolaou, R. M. Denton, A. Lenzen, D. J. Edmonds, A. Li, R. M. Milburn, S. T. Harrison, Stereocontrolled Synthesis of Model Core Systems of Lomaiviticins A and B, Angew. Chem. Int. Ed.
12.B. Liang, J. Liu, Y.-X. Gao, K. Wongkhan, D.-X. Shu, Y. Lan, A. Li, A. S. Batsanov, J. A. H. Howard, T. B. Marder, J.-H. Chen, Z. Yang, Synthesis of Thiourea-Oxazolines, a New Class of Chiral S,N-Heterobidentate Ligands: Application in Pd-Catalyzed Asymmetric Bis(methoxycarbonylation) of Terminal Olefins, Organometallics
13.Z. Xiong, N. Wang, M. Dai, A. Li, J. Chen, Z. Yang, Synthesis of Novel Palladacycles and Their Application in Heck and Suzuki Reactions under Aerobic Conditions, Org. Lett.
14.Y. Zhang, A. Li, Z. Yan, G. Xu, C. Liao, C. Yan, (ZrO2)0.85(REO1.5)0.15 (RE = Sc, Y) solid solutions prepared via three Pechini-type gel routes: 1. gel formation and calcination behaviors, Journal of Solid State Chemistry
15.Y. Zhang, A. Li, Z. Yan, G. Xu, C. Liao, C. Yan, (ZrO2)0.85(REO1.5)0.15 (RE=Sc, Y) solid solutions prepared via three Pechini-type gel routes: 2-sintering and electrical properties, Journal of Solid State Chemistry
16.Y. Zhang, A. Li, Z. Yan, C. Liao, C. Yan, Calcination Time Effects on the Particle Size , Specific Surface Area and Morphology of Rare Earth Oxides (III), Journal of the Chinese Rare Earth Society (Chinese Edition)
17.Y. Zhang, Z. Yan, A. Li, X, Jiang, L. Gu, C. Liao, C. Yan, Effects of Precipitation Conditions on Specific Surface Area and Morphology of Rare Earth Oxides(II), Journal of the Chinese Rare Earth Society (Chinese Edition)
榮譽(yù)記錄
2009年:Eli Lilly Graduate Fellowship;
2008年:國(guó)家優(yōu)秀自費(fèi)留學(xué)生獎(jiǎng)學(xué)金;
2007u20132008年:Bristol-Myers Squibb Graduate Fellowship in Organic Synthesis;
2003年:君政學(xué)者,北京大學(xué);
2000年:全國(guó)高中生化學(xué)競(jìng)賽決賽(冬令營(yíng))一等獎(jiǎng)。
2017年:四面體青年科學(xué)家獎(jiǎng)(Tetrahedron Young Investigator Award)”
2020年9月25日,第二屆“科學(xué)探索獎(jiǎng)”公布了50位青年科學(xué)家獲獎(jiǎng)名單,李昂入選。