研究概述
主要以擬南芥和番茄為研究對象，綜合遺傳學、生物化學、細胞生物學和基因組學等方法探索：1) 植物小非編碼RNA的加工和作用機制，主要聚焦于miRNA加工復合物的動態(tài)調(diào)控機理以及環(huán)形RNA的產(chǎn)生和降解； 2)植物精細胞發(fā)育和父本表觀遺傳信息重編程過程中的表觀遺傳調(diào)控機制，側(cè)重于精細胞中小非編碼RNA的功能研究。
獲獎情況
2013年上海市“浦江人才”
2014年基金委“優(yōu)秀青年科學基金項目”
代表性文章
1.Su C, Li Z, Cheng J, Li L, Zhong S, Liu L, Zheng Y,Zheng B*. (2017). The protein phosphatase 4 and SMEK1 complex dephosphorylates HYL1 to promote miRNA biogenesis by antagonizing the MAPK cascade in Arabidopsis.Developmental cell,41(5), 527-539.
2. Li Z, Wang S, Cheng J, Su C, Zhong S, Liu Q, Fang Y, Yu Y, Lv H, Zheng Y*,Zheng B*. (2016). Intron lariat RNA inhibits microRNA biogenesis by sequestering the dicing complex in Arabidopsis.PLoS genetics,12(11), e1006422.
3.Zheng B, He H, Zheng Y, Wu W, McCormick S*.(2014).An ARID Domain-Containing Protein within Nuclear Bodies Is Required for Sperm Cell Formation inArabidopsis thaliana.PLoS genetics,10(7), e1004421.
4. Scarpina R, Sigaut L, Pietrasant L, McCormick S,Zheng B*,and Muschiettia J* (2013). Cajal bodies are developmentally regulated during pollen development and pollen tube growth inArabidopsis thaliana.Mol Plant.6(4), 1355-1357.
5.Zheng B,Chen X, and McCormick S (2011).The Anaphase-Promoting Complex is a dual integrator that regulates both miRNA-mediated transcriptional regulation ofCyclin B1and degradation of Cyclin B1 during Arabidopsis male gametophyte development.Plant Cell.23:1033-1046.
6.Zheng B,and Chen X (2011). Dynamics of histone H3 lysine 27 trimethylation in Plant development.Current Opinion in Plant Biology.14:123-129.
7.Zheng B, Wang Z, Li S, Yu B, Liu J, and Chen X (2009).Intergenic transcription by RNA polymerase II coordinates PolIV and PolV in siRNA-directed transcriptional gene silencing in Arabidopsis.Genes & Development.23: 2850-2860.
8.Zheng B, Deng Y, Mu J, Ji Z, Xiang T, Niu Q, Chua N-H, and Zuo J (2006).Cytokinin affects circadian-clock oscillation in a phytochrome B- andArabidopsis Response Regulator 4-dependent manner.Physiologia Plantarum.127: 277-292.