復(fù)旦大學(xué)教授
(Shaoning Yu)教授，男，1964年生。1987年畢業(yè)于復(fù)旦大學(xué)物理二系，獲理學(xué)學(xué)士學(xué)位，1990年獲復(fù)旦大學(xué)應(yīng)用化學(xué)碩士學(xué)位，1999年獲中科院應(yīng)用物理所無(wú)機(jī)化學(xué)博士學(xué)位。1999-2001年任海軍醫(yī)學(xué)研究所副研究員，2001-2004年美國(guó)德州大學(xué)醫(yī)學(xué)院博士后，2004-2005年美國(guó)哈佛大學(xué)醫(yī)學(xué)院博士后，2006-2007，耶魯大學(xué)訪問(wèn)教授。發(fā)表論文三十余篇。專業(yè)方向：生物化學(xué)和生物物理。研究興趣：用物理方法研究蛋白質(zhì)構(gòu)象與功能之間的關(guān)系。
研究興趣：用物理方法研究蛋白質(zhì)構(gòu)象與功能之間的關(guān)系。
代表性論文
(Selected Publications)：
1, Xianrong Shen, Huiming Li, Yan Ou, Wenbin Tao, Aichun Dong, Jilie Kong, Chaoneng Ji and Shaoning Yu*. The Secondary Structure of Calcineurin Regulatory Region and It’s Conformational Change induced by Calcium/Calmodulin binding. Journal of Biological Chemistry 2008, 283, 11407-11413.
2, Xianrong Shen, Wenbing Tao, Jilie Kong, and Shaoning Yu . The Role of Loops 3 and 4 in the interdomains and intersubunits communication of E. coli cAMP Receptor Protein. International Journal of Biological Macromolecular 2008, 42, 372-379.
3, Jilie Kong and Shaoning Yu*. Fourier Transform Infrared Spectroscopic Analysis of Protein Secondary Structure (Review). Acta Biochimica et Biophysica Sinica 2007, 39(8), 549-559.
4, Shaoning Yu, Fenghui Fan, Samuel C. Flores, Fang Mei, and Xiaodong Cheng*. Dissecting the Mechanism of Epac Activation via Hydrogen-Deuterium Exchange FT-IR and Structural Modeling. Biochemistry 2006, 45, 15318-15326.
5, Shaoning Yu, Alice Wuu, Reneeta Basu, Michael R. Holbrook, Alan D. T. Barrett*, and J. Ching Lee*. Protein Stability and Structural Dynamics of Envelope Protein Domain III of Mosquito- and Tick-borne Flaviviruses. Biochemistry 2004. 43,9168-9176.
6, Shaoning Yu and J. Ching Lee*. Role of Residue 138 in the Interdomain Hinge region in Transmitting Allosteric Signals for DNA Binding in Escherichia coli cAMP Receptor Protein. Biochemistry 2004. 43, 4662-4669.
7, Shaoning Yu, Fang Mei, J. Ching Lee, and Xiaodong Cheng*. Probing cAMP-Dependent Protein Kinase Holoenzyme Complexes I and II by FT-IR and Chemical Protein Footpringing. Biochemistry 2004. 43, 1908-1920.
8, Shaoning Yu, Lucy L.-Y. Lee, and J. Ching Lee*. Effects of Metabolites on the Structural Dynamics of Rabbit Muscle Pyruvate Kinase. Biophysical Chemistry 2003. 103, 1-11.
