研究方向及興趣：

牛呼吸道細(xì)菌性病原致病機(jī)理及宿主反應(yīng)機(jī)制

微生物代謝與行為關(guān)系

近5年科研成果：

1. Li Nengzhang, Long Q, Du H, Zhang J, Pan T, Wu C, Lei G, Peng Y, Hardwidge PR: High and low-virulent bovine Pasteurella multocida capsular type A isolates exhibit different virulence gene expression patterns in vitro and in vivo[J]. Vet Microbiol 2016, 196:44-49.

2. Wu C, Qin X, Du H, Li Nengzhang, Ren W, Peng Y. The immunological function of GABAergic system [J]. Front Biosci (Landmark Ed). 2017 Mar 1;22:1162-1172.

3. Ren W, Yin J, Xiao H, Chen S, Liu G, Tan B, Li Nnengzhang, Peng Y, Li T, Zeng B, Li W, Wei H, Yin Z, Wu G, Hardwidge PR, Yin Y. Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli?Infection[J]. Front Immunol. 2017 Jan 16;7:685. doi: 10.3389/fimmu.2016.00685

4. Ren W, Yin J, Chen S, Duan J, Liu G, Li T, Li Nengzhang, Peng Y, Tan B, Yin Y.Proteome analysis for the global proteins in the jejunum tissues of enterotoxigenic Escherichia coli -infected piglets[J]. Sci Rep. 2016 May 9;6:25640.

5. Du H, Fang R, Pan T, Li T, Li Nengzhang, He Q, Wu R, Peng Y, Zhou Z: Comparative Genomics Analysis of Two Different Virulent Bovine Pasteurella multocida Isolates[J]. Int J Genomics 2016, 2016:4512493.

6. 李能章,劉舒萍,程蓉,馮思源,張繼鑫,李春明,彭遠(yuǎn)義. 牛A型多殺性巴氏桿菌新型保護(hù)性抗原的篩選及鑒定[J]. 中國(guó)獸醫(yī)科學(xué),2016,(11):1438-1443.

7. 彭遠(yuǎn)義,李能章,程蓉,李杜,趙益萍,劉舒萍. 一種牛源多殺性巴氏桿菌抗體的間接ELISA檢測(cè)試劑盒及其檢測(cè)方法[P]. 重慶：CN106053807A,2016-10-26.

8. 吉佳樂(lè),谷千沖,李秀華,胡治強(qiáng),李能章,彭遠(yuǎn)義. 牛A型多殺性巴氏桿菌三聚體自轉(zhuǎn)運(yùn)蛋白免疫保護(hù)性的研究[J]. 中國(guó)獸醫(yī)科學(xué),2016,(09):1153-1158.

9. Shuai Chen, Liu Shuping, Zhang Fengmei, Ren Wenkai, Li Nengzhang, Yin Jie, et al.. Effects of dietary L-glutamine supplementation on specific and general defense responses in mice immunized with inactivated Pasteurella multocida vaccine [J]. Amino acids.2014, 46(10): 2365-75.

10.? Heng Xiang, Zhang Ruizhi, Li Nengzhang, Vossbrinck Charles R.Searching for convergent evolution in manganese superoxidase dismutase using hydrophobic cluster analysis.Genetics and molecular biology[J]. 2014, 37 (2): 460-74

11.? Neng-Zhang Li, Tian Xia, Ya-Li Xu, Rong-Rong Qiu, Heng Xiang, Dan He, Yuan-Yi Peng.Genome Sequence of Paenibacillus sp. Strain Aloe-11, an endophytic Bacterium with Broad Antimicrobial Activity and Intestinal Colonization Ability[J]. J. Bacteriol. 2012, 194(8):2117-2118.

12.? Wenkai Ren, Lingxiu Zhou, Nengzhang Li, Yan Wang,Gang Liu,Yuanyi Peng* ,Jiannan Ding, Lichuang Cai, Yulong Yin, Guoyao Wu. Dietary arginine supplementation enhances immune responses to inactivated Pasteurella multocida vaccination in mice[J]. BRIT J NUTR. 2013 Mar 14;109(5):867-72.

13.? Wenkai Ren, Shuping Liu, Shuai Chen, Fengmei Zhang, Nengzhang Li, Jie Yin, Yuanyi Peng, Li Wu, Gang Liu, Yulong Yin, Guoyao Wu .Dietary L-glutamine supplementation increases Pasteurella multocida burden and the expression of its major virulence factors in mice[J]. Amino Acids, 2013，45(4): 947-955

14.? Wenkai Ren, Lingxiu Zou, Zheng Ruan, Nengzhang Li, Yan Wang, Yuanyi Peng, Gang Liu, Yulong Yin, Tiejun Li, Yongqing Hou, Guoyao Wu .Dietary L-proline supplementation confers immunostimulatory effects on inactivated Pasteurella multocida vaccine immunized mice[J]. Amino Acids, 2013，45(3): 555-561

15.? W-K. REN, J. YIN, X-P. ZHU, G. LIU, N-Z. LI, Y-Y. PENG and Y-L.YIN. Glutamine, on intestinal inflammation: a mechanistic perspective[J]. EUROPEAN JOURNAL OF INFLAMMATION, Vol. 11, no. 2, 0-0 (2013)

16.? Wenkai Ren, Rui Yu, Gang Liu,Nengzhang Li, Yuanyi Peng, Miaomiao Wu, Yulong Yin, Yinghui Li, Andrew A. Fatufe, Teijun Li. DNA vaccine encoding the major virulence factors of Shiga toxin type 2e(Stx2e)-expressing Escherichia coli induces protection in mice[J]. Vaccine, 2013 Jan 2;31(2):367-72

17.? 李能章，邱榮蓉，黃園媛，鄒靈秀，彭遠(yuǎn)義. 豬繁殖與呼吸綜合征病毒GP5蛋白在釀酒酵母中的定位研究. 中國(guó)預(yù)防獸醫(yī)學(xué)報(bào); 2012,34(8):670-672

18.? 周偉，李能章，魏學(xué)良，胡娟，夏天，王自力，彭遠(yuǎn)義.重慶市某肉牛場(chǎng)牛支原體肺炎的診斷.中國(guó)預(yù)防獸醫(yī)學(xué)報(bào); 2012,34(4):326-328

19.? 周偉，李能章，魏學(xué)良，胡娟，夏天，王自力，彭遠(yuǎn)義. 牛源羊創(chuàng)傷球菌的分離鑒定.中國(guó)預(yù)防獸醫(yī)學(xué)報(bào); 2012,34(7):584-586

20.? 周偉，李能章，魏學(xué)良，胡娟，夏天，王自力，彭遠(yuǎn)義. 雁鴨源莢膜血清A型多殺性巴氏桿菌的分離鑒定.中國(guó)預(yù)防獸醫(yī)學(xué)報(bào); 2012,34(6):498-500。