男，博士，首都師范大學(xué)教授。

1988華中農(nóng)業(yè)大學(xué)微生物專業(yè) 獲理學(xué)學(xué)士學(xué)位

1991華中農(nóng)業(yè)大學(xué)微生物專業(yè) 獲理學(xué)碩士學(xué)位

1995華中農(nóng)業(yè)大學(xué)微生物系 獲博士學(xué)位1991-1995華中農(nóng)業(yè)大學(xué)微生物系 擔(dān)任大學(xué)生“普通生物學(xué)”課程教學(xué)任務(wù)

1995-1997中國農(nóng)業(yè)大學(xué)承擔(dān)碩士、博士生“分子系統(tǒng)學(xué)和微生物進(jìn)化”全部課程，“細(xì)菌遺傳學(xué)”部分內(nèi)容：分子細(xì)菌與植物的相互關(guān)系

1998-1999阿拉巴馬大學(xué)，口腔醫(yī)學(xué)院(Birmingham, USA)博士后, 從事口腔微生物和口腔生物學(xué)研究

2000-2001 依利諾伊大學(xué)醫(yī)學(xué)院(Chicago, USA)助理研究員(Research associate),從事細(xì)胞調(diào)亡和癌癥研究

2001-2002 依利諾伊大學(xué)醫(yī)學(xué)院(Chicago, USA)講師(Instructor), 從事細(xì)胞調(diào)亡和癌癥研究

2003-現(xiàn)在 依利諾伊大學(xué)醫(yī)學(xué)院(Chicago, USA)助理研究教授(Assistant Research Professor/Assistant Professor), 從事細(xì)胞調(diào)亡和癌癥以及分子藥物學(xué)研究

2005-現(xiàn)在首都師范大學(xué)生命科學(xué)學(xué)院, 特聘教授, 從事細(xì)胞調(diào)亡和癌癥以及分子藥物學(xué)研究

學(xué)術(shù)研究協(xié)會(huì)會(huì)員

American Association for Cancer Research

American Society for Microbiology

2002-2005 Role of CDC25A in transformation and breast cancer development. (No. BC010557)美國國防部.(CDMRP/Breast Cancer Research Program).

共主持人(Co-Investigator)

2002-2007 Role of G1-Cdks in immortalization and oncogenesis. (No.CA100204) 美國衛(wèi)生部(NIH/R01), 共主持人(Co-Investigator)

2006-2008 Cdk4在Ink4a/Arf/p53失活相關(guān)的乳腺癌中的作用(30571006)

國家自然科學(xué)基金, 主持人

2005-2010 Role of Cdks in B cell lymphoma (R01 CA113579)

美國衛(wèi)生部(NIH/R01), 主持人

2007-2009 細(xì)胞周期蛋白依賴性激酶4在B細(xì)胞淋巴瘤中的作用。國家自然科學(xué)基金, 主持人

（部分）

Zou X, F Li and H Chen (1997). Characteristics of different plasmids in Rhizobium huakuii strains. Current Microbiology, 35: 215-220.

Zou X, Feng X, Chen W and Li F (1998). Biological behavior of plasmid in Rhizobium sp.strain S25 from Tephrosia candida. Plasmid, 40:158-163.·Caufield P, Y Li and Zou X (1999). Evidence for clonality among African-derived strains of S. mutans. J. Dent. Res. 78, 290.

Zou X, P Caufield, Y Li and F Qi .(2001). Complete nucleotide sequence and characterization ofpUA140, a cryptic plasmid from Streptococcus mutans. Plasmid, 46:77-85

Zou X, Tsutsui T, Ray D, Blomquist JF, Ichijo H, Ucker DS and Kiyokawa H. (2001). The cell cycle-regulatory CDC25A phosphatase inhibits Apoptosis Signal-regulating Kinase 1 . Mol. Cell. Biol. 21:4818-4828.

Zou X, Ray D, Aziyu A, Christov-Tzelkov K, Boiko A, Gudkov A, Kiyokawa H.(2002). Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence. Genes Dev. 16: 2923- 2934.

Jirawatnotai S, Aziyu A, Osmundson E, Moons DS, Zou X, Kineman R, Kiyokawa H.(2004). Cdk4 is indispensable specifically for postnatal proliferation of somato/lactotrophsof the murine pituitary. JBC 279(49):51100-51106.

Ray D, Terao Y,Donzelli M,Ghosh AK,Tsutsui T, Zou X, Varga J, Draetta GF, Kiyokawa H. (2005). The Smad3-mediated signaling of TGF-beta facilitates proteasome-dependent degradation of Cdc25A. Mol. Cell. Biol. 25(8): 3338-3347.

Li Y , Caufield P, Qi F and Zou X. IS1216 and IS199, two functional insertion sequences (IS) in Streptococcus mutans isolated from human dental caries. (submitted).

Aziyu A, Hirai H, Kiyokawa H, Christov-Tzelkov K, Zou X. Cdk4 is required for developmental and oncogenic proliferation of p53-deficient cells. (submitted)

Sandoval R, Xue J, Tian X, Barrett K, Pilkinton M, Ucker DS, Raychaudhuri P, Kineman RD, Luque RM, Baida G, Zou X et al(2006). A mutant allele of BARA/LIN-9 rescues the cdk4-/- phenotype by releasing the repression on E2F-regulated genes. Exp Cell Res. 1;312(13):2465-75.

Zou X etc. (2005). Induction of Cellular Senescence by Cdk4 Disruption:

A Prospective Tool for Tumor Suppression and Regression. (International Patent, ID

No: CW06/NPU)

擅長微生物發(fā)酵,曾獨(dú)立設(shè)計(jì)與創(chuàng)建兩個(gè)小型微生物發(fā)酵工廠