個(gè)人經(jīng)歷
學(xué)習(xí)經(jīng)歷
1997年12月獲無錫輕工業(yè)學(xué)院發(fā)酵工程專業(yè)博士學(xué)位；1989年12月獲無錫輕工業(yè)學(xué)院發(fā)酵工程專業(yè)碩士學(xué)位。
研究經(jīng)歷
2000年6月-2001年6月，香港科技大學(xué)博士后；2003年7月-2004年12月，美國夏威夷大學(xué)訪問科學(xué)家。
社會兼職
Journal of the Science of Food & Agriculture (JSFA)副主編，中國發(fā)酵工業(yè)協(xié)會常務(wù)理事，中國發(fā)酵工業(yè)協(xié)會發(fā)酵工程技術(shù)工作委員會委員，中國釀酒工業(yè)協(xié)會啤酒分會副理事長，中國食品科技學(xué)會第四屆酶制劑專業(yè)委員會委員，江蘇省發(fā)酵工業(yè)協(xié)會副理事長，江蘇省生物技術(shù)協(xié)會常務(wù)理事，華南理工大學(xué)廣東省“發(fā)酵與酶工程”重點(diǎn)實(shí)驗(yàn)室學(xué)術(shù)委員會委員。
研究領(lǐng)域
發(fā)酵過程優(yōu)化與控制，酶工程與技術(shù)，代謝工程技術(shù)
主要論著
主要代表作如下：
1. Zhu Yuhong, Li Jianghua, Liu Long, Du Guocheng, Chen Jian. Production of α-ketoisocaproate via free-whole-cell biotransformation by Rhodococcusopacus DSM 43250 with L-leucine as the substrate. Enzyme and Microbial Technology. 2011, 49: 321-325
2. Zhou Haiyan, Liao Xianyan, Liu Long, Wang Tianwen, Du Guocheng, Chen Jian. Enhanced L-phenylalanine production by recombinant Escherichia coli BR-42 (pAP-B03) resistant to bacteriophage BP-1 via a two-stage feeding approach. Journal of Industrial Microbiology and Biotechnology. 2011, 38: 1219-1227
3. Zhang Zichen, Li Jianghua, Liu Long, Sun Jun, Hua Zhaozhe, Du Guocheng, Chen Jian. Enzymatic transformation of 2-O-α-D-Glucopyranosyl-L-Ascorbic acid (AA-2G) by immobilized α-cyclodextring lucanotransferase from recombinant Escherichia coli. Journal of Molecular Catalysis B: Enzymatic. 2011, 68: 223u2013229
4. Liu Song, Zhang Dongxu, Wang Miao, Cui Wenjing, Chen Kangkang, Liu Yi, Du Guocheng, Chen Jian, Zhou Zhemin. The pro-region of Streptomyces hygroscopicus transglutaminase affects its secretion by Escherichia coli. FEMS Microbiology Letters. 2011. 324: 98-105
5. Lin Jun, Liao Xianyan, Du Guocheng, Chen Jian. Use of Escherichia coli add/ade mutant and Saccharomyces cerevisiae WSH2 to construct a highly efficient coupled system for glutathione production. Enzyme and Microbial Technology. 2010, 48(2): 82-86
6. Wang Zhihao, Wang Yun, Zhang Dongxu, Li Jianghua, Hua Zhaozhe, Du Guocheng, Chen Jian. Enhancement of cell viability and alkaline polygalacturonate lyase production by sorbitol co-feeding with methanol in Pichia pastoris fermentation. Bioresource Technology, 2010, 101: 1318u20131323
7. Liu Zhiyu, Zhang Dongxu, Hua Zhaozhe, Li Jianghua, Du Guocheng and Chen Jian. Improvement of laccase production and its properties by low-energy ion implantation. Bioprocess and Biosystems Engineering. 2010, 33: 639-646
8. Lin Jun, Liao Xianyan, Du Guocheng, Chen Jian. Use of Escherichia coli add/ade mutant and Saccharomyces cerevisiae WSH2 to construct a highly efficient coupled system for glutathione production. Enzyme and Microbial Technology. 2010, 48(2): 82-86
9. Wang Zhihao, Wang Yun, Zhang Dongxu, Li Jianghua, Hua Zhaozhe, Du Guocheng, Chen Jian. Enhancement of cell viability and alkaline polygalacturonate lyase production by sorbitol co-feeding with methanol in Pichia pastoris fermentation. Bioresource Technology, 2010, 101: 1318u20131323
10. Liu Zhiyu, Zhang Dongxu, HuaZhaozhe, Li Jianghua, Du Guocheng and Chen Jian. Improvement of laccase production and its properties by low-energy ion implantation. Bioprocess and Biosystems Engineering. 2010, 33: 639-646
11. Liu Long, Wang Miao, Sun Jun, Du Guocheng, Chen Jian. Application of a novel cavern volume controlled culture model to microbial hyaluronic acid production by batch culture of Streptococcus zooepidemicus. Biochemical Engineering Journal. 2010, 48: 141-147
科研項(xiàng)目
1．重要食品酶微生物發(fā)酵生產(chǎn)與高效制備關(guān)鍵技術(shù)(2011AA100905), 2011-2015年，十二五863課題；
2．解脂亞洛酵母代謝網(wǎng)絡(luò)異位重構(gòu)強(qiáng)化alpha-酮戊二酸積累（31171638），2012-2015年，國家自然科學(xué)基金項(xiàng)目；
科研成果及獎(jiǎng)勵(lì)
近5年來完成或承擔(dān)了包括國家863項(xiàng)目、國家自然科學(xué)基金等在內(nèi)的國家、省部級項(xiàng)目11項(xiàng)。發(fā)表SCI收錄論文102篇，其中第一作者/責(zé)任作者SCI論文43篇；出版相關(guān)著作4部；獲授權(quán)發(fā)明專利45項(xiàng)，申請發(fā)明專利52項(xiàng)；獲得6項(xiàng)國家科技進(jìn)步獎(jiǎng)二等獎(jiǎng)和省部級獎(jiǎng)勵(lì)。獲江蘇省教學(xué)成果特等獎(jiǎng)2項(xiàng)、國家教學(xué)成果二等獎(jiǎng)1項(xiàng)。擔(dān)任國家精品課程“生化工程”的負(fù)責(zé)人。09年入選新世紀(jì)百千萬人才工程國家級人選、獲全國優(yōu)秀教師稱號。擔(dān)任Journal of the Science of Food and Agriculture副主編。
