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  • 董琳

    董琳(川大教授)

    董琳,女,四川人,博士,四川大學(xué)華西藥學(xué)院教授,博士生導(dǎo)師。


    人物經(jīng)歷

    1994-1998鄭州大學(xué)化學(xué)系,化學(xué)專(zhuān)業(yè),理學(xué)學(xué)士

    2001-2006中國(guó)科學(xué)院成都有機(jī)化學(xué)研究所,有機(jī)化學(xué)專(zhuān)業(yè),碩博連讀,師從龔流柱教授

    2006-2009 澳大利亞昆士蘭大學(xué)化學(xué)系,博士后,師從Craig M. Williams教授

    2009-2011 新加坡科技研究局化學(xué)與工程科學(xué)研究院,研究科學(xué)家,師從著名化學(xué)家K. C. Nicolaou 教授

    2011-2016四川大學(xué)華西藥學(xué)院,副教授

    董琳

    2016-至今四川大學(xué)華西藥學(xué)院,教授

    獲獎(jiǎng)情況

    1、2012年 四川大學(xué)優(yōu)秀青年骨干教師獎(jiǎng)勵(lì)

    2、2014年 大學(xué)生課外科技實(shí)踐活動(dòng)優(yōu)秀指導(dǎo)教師

    3、2016年 四川大學(xué)唐立新優(yōu)秀學(xué)者獎(jiǎng)

    研究方向

    1、有機(jī)合成方法學(xué)研究

    2、天然產(chǎn)物與藥物合成

    科研項(xiàng)目

    1、2013-2015國(guó)家自然科學(xué)基金-青年基金

    2、2016-2019 國(guó)家自然科學(xué)基金-面上項(xiàng)目

    發(fā)表論文

    [1] Liu, C.-F.; Zhang, G.-T.; Sun, J.-S.;Dong, L.*, “Access to π-conjugated azaindole derivatives via rhodium(III)-catalyzed cascade reaction of azaindoles and diazo compounds”,Org. Biomol. Chem.2017,15, 2902u20132905.

    [2] Xia, Y.-Q.;Dong, L.*, “Ruthenium(II)-Catalyzed Indolo[2,1-a]isoquinolines Synthesis by Tandem C?H Allylation and Oxidative Cyclization of 2-Phenylindoles with Allyl Carbonates”,Org. Lett.,2017,19, 2258?2261.

    [3] Zhang, G.-T.;Dong, L.*, “Synthesis of Polycyclic Amides via Tandem RhIII-Catalyzed C-H

    Activation and Annulation from Dioxazolones and Alkynes”,Asia. J. Org. Chem.2017,6, 812 u2013 816.

    [4] Wu, L.;Dong, L.*, “The application of Morita-Baylis-Hillman reaction: Synthetic studies on perophoramidine”,Tetrahedron2017, 73,3966-3972.

    [5] Li, S.-S.; Liu, C.-F.; Zhang, G.-T.; Xia, Y.-Q.; Li, W.-H.;Dong, L.*, “A Convenient One-Pot Route to Screw-Shaped [5]Azahelicenes via Rhodium(III)-Catalyzed Multiple C-H Bond Activation”,Chem. Asia. J.2017,12, 415-418.

    [6] Li, S.-S.; Xia, Y.-Q.; Liu, C.-F.; Zhang, G.-T.; Su, F.; Zhang, X.-M.;Dong, L.*, “Diverse Reactivity in a Rhodium(III)-Catalyzed Vinylic sp2 Cu2013H Bond Functionalization: Synthesis of Fused Polycyclic Heteroarenes or Conjugated Dienes”,Adv. Synth. Catal.2016,358(23), 3724 u20133729.

    [7] Lin, H.;Dong, L.*, “One-Pot Synthesis of Decahydropyrene via Tandem C?H Activation/Intramolecular Diels?Alder/1,3-Dipolar Cycloaddition”;Org. Lett.,2016,18, 5524?5527.

    [8] Li, S.-S.; Xia, Y.-Q.; Hu, F.-Z.; Liu, C.-F.; Su, F.;Dong, L.*, “Ir-Catalyzed One-Pot Cascade ynthesis of Pentacyclic-Fused Carbazoles from Indoles and Diazoes”,Chem. Asia. J.2016,11,3165 u2013 3168.

    [9] Li, W.-H.; Wu, L.; Li, S.-S.; Liu, C.-F.; Zhang, G.-T.;Dong, L.*, “Rhodium-Catalyzed Hydrogen-Releasing ortho-Alkenylation of 7-Azaindoles”,Chem. Eur. J.2016,22(50), 17926u2013 17929.

    [10] Zhu, Y.-Q.; Qin, L.; Song, Q.; Su, F.; Xu, Y.-J.;Dong, L.*, “Rhodium(III)-catalyzed ortho-alkenylation using a cyclic N-phosphoryl ketimine as the directing group”,Org. Biomol. Chem.2016,14, 9472u20139475.

    [11] Li, S.-S.; Wu, L.; Qin, L.; Zhu, Y.-Q.;Su, F.; Xu, Y.-J.;Dong, L.*, “Iridium(III)-Catalyzed Tandem [3 + 2] Annulation: Synthesis of Spirocyclic Phosphoramide Derivatives”,Org. Lett.,2016,18(17), 4214u20134217.

    [12] Li, S.-S.; Li, W.-H.; Zhang, G.-T.; Xia, Y.-Q.; Liu, C.-F.; Su, F.; Zhang, X.-M.;Dong, L.*, “One-pot construction of fused polycyclic heteroarenes involving 7-azaindoles and α,β-unsaturated ketones”,Org. Biomol. Chem.,2016, 14,7859u20137863.

    [13] Wang, C.-Q.; Zhang, W., Lin, H.; Su, F.;Dong, L.*, “Synthesis of Isoquinolinium Salts via Rh(III)-catalyzed Oxidative Annulation between Aldehyde Imines and Alkynes”,HETEROCYCLES,2016, 92(9),1674-1686.

    [14] Li, S.-S.; Lin, H.; Liu, C.-F.; Xia, Y.-Q.; Zhang, X.-M.;Dong, L.*, “Rhodium-Catalyzed Tandem Annulation Reactions of 7-Azaindoles with Electron-Deficient Olefins via Double C-H Activation”,Adv. Synth. Catal.2016, 358,1595 u20131601.

    [15] Li, S.-S.; Liu, C.-F.; Xia, Y.-Q.; Li, W.-H.; Zhang, G.-T.; Zhang, X.-M.;Dong, L.*, “A unique annulation of 7-azaindoles with alkenyl esters to produce π-conjugated 7-azaindole derivatives”,Org. Biomol. Chem.,2016, 14,5214u20135218.

    [16] Li, S.-S.; Qin, L.;Dong, L.*, “Rhodium-catalyzed Cu2013C coupling reactions via double Cu2013H activation”,Org. Biomol. Chem.,2016,14,4554-4570.

    [17] Li, S.-S.; Wang, C.-Q.; Li, W.-H.; Zhang, X.-M.;Dong, L.*, “Rhodium-catalyzed selective oxidative coupling of 7-azaindoles”,Tetrahedron2016, 72,2581-2586.

    [18] Zhang, W., Wang, C.-Q.; Lin, H.;Dong, L.*, Xu, Y.-J, “Synthesis of Mesoionic Isoquinolines by Rhodium(III)-Catalyzed C-H Activation”,Chem. Eur. J.2016, 22,907-910.

    [19] Li, S.-S.; Wang, C.-Q.; Lin, H.; Zhang, X.-M.;Dong, L.*, “Rhodium(III)-catalyzed Cu2013C coupling of 7-azaindoles with vinyl acetates and allyl acetates”,Org. Biomol. Chem.,2016,14, 229u2013237.

    [20] Zhu, Y.-Q.;Dong, L.*, “One-Pot Synthesis of Polysubstituted Spirofluorene?Indene via Ru(II)-Catalyzed [3 + 2] Annulation and Intramolecular Friedel?Crafts Cyclization”,J. Org. Chem.2015,80 (20), 9973?9979

    [21] Lin, H.; Li, S.-S.;Dong, L.*, “Synthesis of indoles and polycyclic amides via ruthenium(II)-catalyzed C-H activation and annulation”,Org. Biomol. Chem.2015,13, 11228-11234

    [22] Li, S.-S.; Wang, C.-Q.; Lin, H.; Zhang, X.-M.;Dong, L.*, “Rhodium(III)-Catalyzed Oxidative Annulation of 7u2011Azaindoles and Alkynes via Double C?H Activation”O(jiān)rg. Lett.2015,17, 3018-3021.

    [23] Huang, J.-R.; Qin, L.; Zhu, Y.-Q.; Song, Q.;Dong, L.*“Multi-site Cyclization via Initial C-H Activation Using Rhodium(III) Catalyst: Rapid Assembly of Frameworks Containing Indoles and Indolins”Chem. Comm.2015,51, 2844-2847.

    [24] Li, S.-S.; Lin, H.; Zhang, X.-M.;Dong, L.* “Ruthenium-Catalyzed Direct C3 Alkylation of Indoles with α,β-Unsaturated Ketones”,Org. Biomol. Chem.2015,13,1254-1263.

    [25] Zhang, W.; Zhang, Q.-R.;Dong, L.* “Rhodium-catalyzed [2+2+2] cycloaddition reactions of terminal alkynes with N-sulfonyl ketimines”,Tetrahedron Letters2015,56, 546u2013548.

    [26] Zhang, Q.-R.; Huang, J.-R.; Zhang, W.;Dong, L.* “Highly Functionalized Pyridines Synthesis fromN-Sulfonyl Ketimines and Alkynes Using N-S Bond as an Internal Oxidant”,Org. Lett.2014,16, 1684-1687.

    [27] Huang, J.-R.; Song, Q.; Zhu, Y.-Q.; Qin, L.; Qian, Z.-Y.;Dong, L.* “Rhodium(III)-Catalyzed Three-Component Reactions of Imines, Alkynes, and Aldehydes via Cu2013H Activation”,Chem. Eur. J.2014,20, 16882-16886.

    [28]Dong, L.*; Qu, C.-H.; Huang, J.-R.; Zhang, W.; Zhang, Q.-R.; Deng, J.-G. “Rhodium-catalyzed Spirocyclic Sultam Synthesis by [3+2] Annulation with CyclicN-Sulfonyl Ketimines and Alkynes”,Chem. Eur. J.2013,19, 16537-16540.

    [29]Dong, L.*; Huang, J.-R.; Qu, C.-H.; Zhang, Q.-R.; Zhang, W.; Han, B.; Peng, C.* “Rhodium(III)-catalyzed vinylic sp2 Cu2013H bond functionalization: efficient synthesis of pyrido[1,2-α]-benzimidazoles and imidazo[1,2-α]pyridines”,Org. Biomol. Chem.2013,11, 6142u20136149.

    [30] Huang, J.-R.; Zhang, Q.-R.; Qu, C.-H.; Sun, X.-H.;Dong, L.* Chen. Y.-C.* “Rhodium(III)-Catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-Substituted Imidazoles and Alkynes by Double C-H Activation”,Org. Lett.2013,15, 1878-1881.

    [31] Huang, J.-R.;Dong, L.*; Han, B.; Peng, C.; Chen. Y.-C. “Synthesis of Aza-Fused Polycyclic Quinolines via Double C-H Bond Activations”,Chem. Eur. J.2012,18, 8896-8898.

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