研究方向
新藥創(chuàng)制方法學(xué)及現(xiàn)代中藥設(shè)計技術(shù) 藥品質(zhì)量檢測方法學(xué)及質(zhì)量控制技術(shù) 工業(yè)藥學(xué)及先進(jìn)制藥技術(shù)研究 藥物分析信息學(xué)與臨床藥學(xué)研究學(xué)院副院長、浙江大學(xué)藥物信息學(xué)研究所所長、國家中醫(yī)藥管理局計算機(jī)輔助中藥分析III級實(shí)驗(yàn)室主任
社會兼職
國家藥典委員會委員、國家藥品審評專家、教育部高等學(xué)校藥學(xué)類中藥專業(yè)教學(xué)指導(dǎo)委員會委員、中國藥學(xué)會中藥及天然藥物專業(yè)委員會理事、中國中醫(yī)藥信息數(shù)字化專業(yè)委員會副主任、中國中醫(yī)藥研究促進(jìn)會理事、中國藥材GAP研究促進(jìn)會理事、浙江省藥學(xué)會常務(wù)理事及制藥工程專業(yè)委員會主任、浙江省中醫(yī)藥學(xué)會博士學(xué)術(shù)委員會副主任; 《化學(xué)學(xué)報》、《中國中藥雜志》、《中草藥》、《藥物分析雜志》等刊物編委; 上海交通大學(xué)計算機(jī)系兼職教授、上海中醫(yī)藥大學(xué)兼職教授、中藥標(biāo)準(zhǔn)化教育部重點(diǎn)實(shí)驗(yàn)室學(xué)術(shù)委員
主要榮譽(yù)
國務(wù)院政府特殊津貼專家,天津市人民政府特聘專家,浙江省有突出貢獻(xiàn)中青年專家,浙江省151人才工程重點(diǎn)資助人員、浙江省新世紀(jì)學(xué)術(shù)和技術(shù)帶頭人第一層次。 作為第一獲獎?wù)攉@國家科技進(jìn)步二等獎1項(xiàng)、省級科技進(jìn)步二等獎5項(xiàng)、省級科技進(jìn)步三等獎2項(xiàng)、中華中醫(yī)藥學(xué)會科學(xué)技術(shù)獎3項(xiàng);作為第二獲獎?wù)攉@浙江省教學(xué)成果二等獎及高校優(yōu)秀教材二等獎各1項(xiàng);作為第三獲獎?wù)攉@2005年天津市自然科學(xué)一等獎。指導(dǎo)的博士生獲2005年全國優(yōu)秀博士論文提名論文。
2017年3月31日,中國工程院頒布了增選有效候選人提名名單,程翼宇在列。
研究課題
近5年主持研究或負(fù)責(zé)完成國家973計劃項(xiàng)目、國家自然科學(xué)基金重點(diǎn)項(xiàng)目、國家科技攻關(guān)重點(diǎn)項(xiàng)目等國家重要課題5項(xiàng)。此外,還承擔(dān)了一批國家級普通課題及橫向科研重大課題10余項(xiàng)。
主要論文
近年作為責(zé)任作者發(fā)表論文200余篇,其中被SCI收錄120余篇,IF>3論文20篇。代表性論文有: 1. Ma, GL; Cheng, YY*,Predicting Caco-2 permeability using support vector machine and Chemistry Development Kit,JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES, 9 (2): 210-221 MAY-AUG 2006 2. Zhang, YF; Shi, QR; Shi, PY; Zhang, WD; Cheng, YY*,Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin-Guo-Lan (Tinospora sagittata and Tinospora capillipes) by high-performance liquid chromatography/electrospray ionization with multistage mass spectrometry,RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 20 (15): 2328-2342 2006 3. Luo, PH; He, QJ; He, XG; Hu, YZ; Lu, W; Cheng, YY*; Yang, B,Potent antitumor activity of 10-methoxy-9-nitrocamptothecin,MOLECULAR CANCER THERAPEUTICS, 5 (4): 962-968 APR 2006 4. Cheng, YY*; Wang, Y; Wang, XW,A causal relationship discovery A, 1109 (2): 279-284 MAR 24 2006 7. Yu, K; Lin, ZY; Cheng, YY*,Optimization of the buffer system of micellar electrokinetic capillary chromatography for the separation of the active components in Chinese medicine ’SHUANGDAN’ granule by genetic algorithm,ANALYTICA CHIMICA ACTA, 562 (1): 66-72 MAR 9 2006 8. Fan, XH; Wang, Y; Cheng, YY*,LC/MS fingerprinting of Shenmai injection: A novel approach to quality control of herbal medicines,JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 40 (3): 591-597 FEB 24 2006 9. Cheng, YY*; Yuan, H,Quantitative study of electrostatic and steric effects on physicochemical property and biological activity,JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 24 (4): 219-226 JAN 2006 10. Fan, XH; Cheng, YY*; Ye, ZL; Lin, RC; Qian, ZZ,Multiple chromatographic fingerprinting and its application to the quality control of herbal medicines,ANALYTICA CHIMICA ACTA, 555 (2): 217-224 JAN 12 2006 11. Liu, L; Ning, ZQ; Shan, S; Zhang, K; Deng, T; Lu, XP; Cheng, YY*,Phthalide lactones from Ligusticum chuanxiong inhibit lipopolysaccharide-induced TNF-alpha production and TNF-alpha-mediated NF-kappa B activation, 48 (4): 361-367 AUG 2005 13. Yan, SK; Xin, WF; Luo, GA; Wang, YM; Cheng, YY*,An approach to develop two-dimensional fingerprint for the quality control of Qingkailing injection by high-performance liquid chromatography A, 1090 (1-2): 90-97 OCT 7 2005 14. Wu, YJ; Chen, JJ; Cheng, YY*,A sensitive and specific HPLC-MS, 382 (7): 1595-1600 AUG 2005 15. Cheng, YY*; Chen, MJ; Welsh, WJ,F(xiàn)ractal fingerprinting of chromatographic profiles based on wavelet analysis and its application to characterize the quality grade of medicinal herbs,JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 43 (6): 1959-1965 NOV-DEC 2003 16. Cheng, YY*; Chen, MJ; Tong, WD,An approach to comparative analysis of chromatographic fingerprints for assuring the quality of botanical drugs,JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 43 (3): 1068-1076 MAY-JUN 2003 17. Yang, NL; Cheng, YY*; Wu, YJ,A new method for fast and nondestructive analysis of saponins in Panax notoginseng herb by near infrared spectroscopy,ACTA CHIMICA SINICA, 61 (3): 393-398 MAR 2003 18. Zhang, HJ; Wu, YJ; Cheng, YY*,Analysis of ’SHENMAI’ injection by HPLC/MS/MS,JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 31 (1): 175-183 FEB 5 2003 19. Cheng, YY*; Chen, MJ; Wu, YJ,Measures for determining the similarity of chemical fingerprint and a method of evaluating the measures,ACTA CHIMICA SINICA, 60 (11): 2017-2021 NOV 2002 20. Cheng, YY*; Yu, J; Wu, YJ,A visualization method of chromatographic data for discovering fingerprint features of natural herbal medicines,ACTA CHIMICA SINICA, 60 (2): 328-333 FEB 2002 21. Cheng, YY*; Zhao, MJ,A type of fuzzy classification neural networks for complex nonlinear chemical pattern recognition,CHEMICAL JOURNAL OF CHINESE UNIVERSITIES, 22 (11): 1813-1818 NOV 2001 22. Zhao, MJ; Cheng, YY*; Chen, WZ,A stepwise method for extracting the characteristic of complex chemical pattern in natural plants,ACTA CHIMICA SINICA, 59 (6): 842-846 2001
