侯亞義，男，博士、教授、博士生導(dǎo)師，江蘇省免疫學(xué)會常務(wù)理事。現(xiàn)主要從事細(xì)胞與分子免疫學(xué)研究，主要聚焦于自身免疫性疾病中免疫細(xì)胞功能和信號傳導(dǎo)的調(diào)控以及腫瘤的分子免疫機(jī)制與治療等。曾主持國家自然科學(xué)基金、教育部科學(xué)技術(shù)重點(diǎn)基金及橫向科研等項(xiàng)目，參與江蘇省衛(wèi)生廳科學(xué)基金等項(xiàng)目�，F(xiàn)主持國家自然科學(xué)基金、江蘇省自然科學(xué)基金及江蘇省衛(wèi)生廳重大科學(xué)基金，參與國家科技重大專項(xiàng)項(xiàng)目、“973計(jì)劃”、國家自然科學(xué)基金委重大研究計(jì)劃、江蘇省衛(wèi)生廳“興衛(wèi)工程”基金及江蘇省科學(xué)技術(shù)廳高技術(shù)研究（醫(yī)藥）重大項(xiàng)目等項(xiàng)目。江蘇省“六大人才高峰”第五批高層次人才。2005年參編專著1部(科學(xué)出版社)。已發(fā)表國內(nèi)外論文106篇，其中SCI論文49篇。申請專利3項(xiàng)。

1. Mesenchymal Stem Cell Transplantation Reverses Multi-Organ Dysfunction in Systemic Lupus Erythematosus Mice and Humans. Stem cell. 2009.

2. Changes in NK Cell Counts and Receptor Expressions and Emergence of CD3dimCD56+ Cells in HIV-1 Infected Patients in China. Viral Immunology, 22(2):1-12, 2009.

3. 17β-Estradiol Suppresses Cytotoxicity and Proliferative Capacity of Murine Splenic NK1.1+ Cells. Cell & Mol Immunology. 2008;5(5):357-364.

4. Transdifferentiation of mesenchymal stem cells derived-from human fetal lung to hepatocyte-like cells. Cell Biology Int, 2008, 32:1091-1098.

5. Protein expression and purification of human Zbtb7A in Pichia pastoris via gene codon optimization and synthesis. Protein Expression and Purification, 2008, 60: 97-102.

6. Estrogen modulates bone marrow-derived DCs in SLE murine model-(NZB x NZW) F1 female mice. Immunol Invest,2008, 37(3):227-43.

7. Over-expressed and truncated midkines promote proliferation of BGC823 cells in vitro and tumor growth in vivo. WJG, 2008, 14(12): 1858-1865.

8. Lung Cancer Risk Associated with Thr495Pro Polymorphism of GHR in Chinese Population. Jpn J Clin Oncol 2008; 38(4)308u2013316.

9. Estrogen distinctively modulates spleen DC from (NZB · NZW) F1 female mice in various disease development stages. Cell Immunology, 2007, 248: 95u2013102

10. siRNA targeting midkine inhibits gastric cancer cells growth and induces apoptosis involved caspase-3,8,9 activation and mitochondrial depolarization. J Biomed Science, 2007, 14(6):783-95.

11. Modulation of 17beta-estradiol on the number and cytotoxicity of NK cells in vivo related to MCM and activating receptors. Int Immunopharmacol. 2007, 7(13):1765-75.

12. Changes in the Ratio of Tc1/Tc2 and h1/Th2 Cells but Not in Subtypes of NK-Cells in Preeclampsia. Int. J. Mol. Sci. 2007, 8, 492-504

13. Polarization of T Lymphocytes Is Regulated by Mesenchymal Stem Cells in NZBWF1 and BALB/c Mice. Int. J. Mol. Sci. 2007, 8, 455-469

14. Abnormal surface markers expression on bone marrow CD34+ cells and correlation with disease activity in patients with systemic lupus erythematosus. Clin Rheumatol, 2007, 26(12):2073-9

15. Abnormality of bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus. Lupus, 2007, 16 (2): 121-128

16. The Expression and Location of Midkine in Gastric Carcinomas of Chinese Patients. Cell & Mol Immunology. 2007, 4(2):135-140.

17. Different characters of spleen OX-62-positive dendritic cells between Fischer and Lewis rat. Cell & Mol Immunology, 2006, 3(2): 145-150.

18. Liposomal plasmid DNA encoding human thymosin α1 and interferon ω1 potently inhibits liver tumor growth in ICR mice. J Gastroenterol and Hepatol. 2006, 21: 1538u20131543

19. Progesterone is involved in the maturation of murine spleen CD11c-positive dendritic cells. Steroids, 2006, 71: 922u2013929.

20. Prolactin regulates phenotype, functions and cytokine expression of mouse spleen dendritic cells. Int Immunopharmacol. 2006, 6:1478-1486.

21. Progesterone Regulates Mouse Dendritic Cells Differentiation and Maturation. Int Immunopharmacol, 2006, 6: 830-838.

22. Effects of 17β-estrodial on the maturation, nuclear factor kappa B and functions of murine spleen CD11c positive dendritic cells. Mol Immunology, 43(4):357-366, 2006.

23. Nonylphenol-induced thymocyte apoptosis involved caspase-3 activation and mitochondrial depolarization. Mol Immunology, 2006 ，43：915-926.

雌激素通過MCM6調(diào)控樹突狀細(xì)胞功能及其TLR9信號轉(zhuǎn)導(dǎo)的機(jī)制研究。國家自然科學(xué)基金資助項(xiàng)目（30771959）。2008.1-2010.12。

新型抗癌藥物SapC-DOPS的開發(fā)研究。江蘇省科學(xué)技術(shù)廳高技術(shù)研究（醫(yī)藥）重大項(xiàng)目（BG2007604）。2007.03-2010.2。

從母胎界面免疫調(diào)節(jié)異常探索妊高癥的預(yù)測方法。江蘇省衛(wèi)生廳科技項(xiàng)目（H200754 ）。2007.10-2010.9。

高危妊娠患者母胎界面免疫學(xué)的研究（XK200709）。江蘇省衛(wèi)生廳“興衛(wèi)工程”基金。2007-2012。

調(diào)控Toll樣受體的新共生菌產(chǎn)物研究。國家自然科學(xué)基金委重大研究計(jì)劃（90813036）。2009.1-2012.12。

艾滋病生物預(yù)防技術(shù)研究與產(chǎn)品研制。國家科技重大專項(xiàng)項(xiàng)目（2008ZX10001-015）。2008-2010。

2002年曾獲南京市科技進(jìn)步三等獎(jiǎng)1項(xiàng)；

2005年度教育部提名國家科學(xué)技術(shù)獎(jiǎng)受獎(jiǎng)項(xiàng)目(科技進(jìn)步獎(jiǎng)二等)1項(xiàng)；

2007年度江蘇省科技進(jìn)步獎(jiǎng)三等獎(jiǎng)1項(xiàng)。