1. 微生物遺傳學(xué)

1）已建立以λ溶原菌作為一種細(xì)胞模式，深入研究λ原噬菌體紫外誘導(dǎo)的自由基機(jī)理；

2）影響微生物代謝調(diào)控的功能性基因及其克隆與表達(dá)；

3）自由基對(duì)微生物細(xì)胞程序性死亡、發(fā)育與分化的影響。

2. 系統(tǒng)微生物學(xué)

1）原核生物系統(tǒng)學(xué)研究（典型分類(lèi)學(xué)、化學(xué)分類(lèi)以及分子分類(lèi)）；

2）產(chǎn)自由基清除劑微生物資源的研究；

3）微生物資源整合、開(kāi)發(fā)與應(yīng)用。

教學(xué)情況（課程名稱(chēng)，學(xué)時(shí)，授課對(duì)象等）：

微生物學(xué)實(shí)驗(yàn) 54學(xué)時(shí) 生科院、藥學(xué)院、醫(yī)學(xué)院 本科生

雙學(xué)位班、東湖分校等 本科生

微生物生理學(xué) 36學(xué)時(shí) 生科院、藥學(xué)院 (部分) 本科生

系統(tǒng)微生物學(xué) 54學(xué)時(shí) 微生物學(xué)專(zhuān)業(yè) 碩士研究生

1．Suhua Zhu, Chengxiang Fang*, Shiqiao Zhu, et al. (2001). Inhibitory effects of Gynostemma pentaphyllum on the UV induction of bactreiophage lambda in lysogenic Escherichia coli. Current Microbiology, 43 (4) :299-301

2. Shiqiao Zhu, Chengxiang Fang*, Suhua Zhu, Luozhen Zhang, Chengpeng Fan, Junxiang Zhang. (2004) Inductive Effect of hypoxanthine-xanthine oxidase system. Microbiology, 73 (1): 42-46

3．Yancheng Liu, Qiuju Zhang, Chengxiang Fang*, Shiqiao Zhu, Yali Tang, Shaoyi Huang. (2005). Inhibitory effects of glutathione on the UV induction of bacterio-phage lambda in lysogenic Escherichia coli. Arch. Microbiol., 183 (6):1-6

4. Hymenobacter tibetensis sp. nov., a UV-resistant bacterium isolated from Qinghai-Tibet plateau.Dai J, Wang Y, Zhang L, Tang Y, Luo X, An H, Fang C.

Syst Appl Microbiol. 2009

5. Cohnella luojiensis sp. nov., isolated from soil of a Euphrates poplar forest.

Cai F, Wang Y, Qi H, Dai J, Yu B, An H, Rahman E, Fang C.

Int J Syst Evol Microbiol. 2009 Aug 21.

Niastella populi sp. nov., isolated from soil of a Euphrates poplar (Populus euphratica) forest, and emended description of the genus Niastella.

Zhang K, Wang Y, Tang Y, Dai J, Zhang L, An H, Luo G, Rahman E, Fang C.

Int J Syst Evol Microbiol. 2009 Aug 4. [

5.

Description of Pontibacter xinjiangensis sp. nov., in the phylum Bacteroidetes, and reclassification of Effluviibacter roseus as Pontibacter roseus comb. nov.

Wang Y, Zhang K, Cai F, Zhang L, Tang Y, Dai J, Fang C.

Int J Syst Evol Microbiol. 2009 Jul 31. [

6.

Pedobacter glucosidilyticus sp. nov., isolated from dry riverbed soil.

Luo X, Wang Z, Dai J, Zhang L, Li J, Tang Y, Wang Y, Fang C.

Int J Syst Evol Microbiol. 2009 Jul 31.

7.

Parasegetibacter luojiensis gen. nov., sp. nov., a novel member of the phylum Bacteroidetes, isolated from a Euphrates poplar forest.

Zhang K, Tang Y, Zhang L, Dai J, Wang Y, Luo X, Liu M, Luo G, Fang C.

Int J Syst Evol Microbiol. 2009 Jul 30. [

8.

Planobacterium taklimakanense gen. nov., sp. nov., a member of the family Flavobacteriaceae that exhibits swimming motility, isolated from desert soil.

Peng F, Liu M, Zhang L, Dai J, Luo X, An H, Fang C.

Int J Syst Evol Microbiol. 2009 Jul;59(Pt 7):1672-8.

9.

Bacillus korlensis sp. nov., a moderately halotolerant bacterium isolated from a sand soil sample in China.

Zhang L, Wang Y, Dai J, Tang Y, Yang Q, Luo X, Fang C.

Int J Syst Evol Microbiol. 2009 Jul;59(Pt 7):1787-92.

10.

Skermanella xinjiangensis sp. nov., isolated from the desert of Xinjiang, China.

An H, Zhang L, Tang Y, Luo X, Sun T, Li Y, Wang Y, Dai J, Fang C.

Int J Syst Evol Microbiol. 2009 Jun;59(Pt 6):1531-4.

11.

Mucilaginibacter ximonensis sp. nov., isolated from Tibetan soil.

Luo X, Zhang L, Dai J, Liu M, Zhang K, An H, Fang C.

Int J Syst Evol Microbiol. 2009 Jun;59(Pt 6):1447-50.

12.

Pseudomonas xinjiangensis sp. nov., a moderately thermotolerant bacterium isolated from desert sand.

Liu M, Luo X, Zhang L, Dai J, Wang Y, Tang Y, Li J, Sun T, Fang C.

Int J Syst Evol Microbiol. 2009 Jun;59(Pt 6):1286-9.

13.

Kineococcus xinjiangensis sp. nov., isolated from desert sand.

Liu M, Peng F, Wang Y, Zhang K, Chen G, Fang C.

Int J Syst Evol Microbiol. 2009 May;59(Pt 5):1090-3.

14.

Lysobacter ximonensis sp. nov., isolated from soil.

Wang Y, Dai J, Zhang L, Luo X, Li Y, Chen G, Tang Y, Meng Y, Fang C.

Int J Syst Evol Microbiol. 2009 Apr;59(Pt 4):786-9.

15.

Deinococcus xinjiangensis sp. nov., isolated from desert soil.

Peng F, Zhang L, Luo X, Dai J, An H, Tang Y, Fang C.

Int J Syst Evol Microbiol. 2009 Apr;59(Pt 4):709-13.

16.

Hymenobacter deserti sp. nov., isolated from the desert of Xinjiang, China.

Zhang L, Dai J, Tang Y, Luo X, Wang Y, An H, Fang C, Zhang C.

Int J Syst Evol Microbiol. 2009 Jan;59(Pt 1):77-82.

17.

Dyadobacter alkalitolerans sp. nov., isolated from desert sand.

Tang Y, Dai J, Zhang L, Mo Z, Wang Y, Li Y, Ji S, Fang C, Zheng C.

Int J Syst Evol Microbiol. 2009 Jan;59(Pt 1):60-4.

18.

Paenibacillus tarimensis sp. nov., isolated from sand in Xinjiang, China.

Wang M, Yang M, Zhou G, Luo X, Zhang L, Tang Y, Fang C.

Int J Syst Evol Microbiol. 2008 Sep;58(Pt 9):2081-5.

19.

Nesterenkonia flava sp. nov., isolated from paper-mill effluent.

Luo HY, Miao LH, Fang C, Yang PL, Wang YR, Shi PJ, Yao B, Fan YL.

Int J Syst Evol Microbiol. 2008 Aug;58(Pt 8):1927-30.

20.

Aeromicrobium flavum sp. nov., isolated from air.

Tang Y, Zhou G, Zhang L, Mao J, Luo X, Wang M, Fang C.

21.Kocuria flava sp. nov. and Kocuria turfanensis sp. nov., airborne actinobacteria isolated from Xinjiang, China.

Zhou G, Luo X, Tang Y, Zhang L, Yang Q, Qiu Y, Fang C.

Int J Syst Evol Microbiol. 2008 Jun;58(Pt 6):1304-7.

22.

Pontibacter korlensis sp. nov., isolated from the desert of Xinjiang, China.

Zhang L, Zhang Q, Luo X, Tang Y, Dai J, Li Y, Wang Y, Chen G, Fang C.

Int J Syst Evol Microbiol. 2008 May;58(Pt 5):1210-4.

23.

Hymenobacter xinjiangensis sp. nov., a radiation-resistant bacterium isolated from the desert of Xinjiang, China.

Zhang Q, Liu C, Tang Y, Zhou G, Shen P, Fang C, Yokota A.

Int J Syst Evol Microbiol. 2007 Aug;57(Pt 8):1752-6.

24.

Knockout of crtB or crtI gene blocks the carotenoid biosynthetic pathway in Deinococcus radiodurans R1 and influences its resistance to oxidative DNA-damaging agents due to change of free radicals scavenging ability.

Zhang L, Yang Q, Luo X, Fang C, Zhang Q, Tang Y.

Arch Microbiol. 2007 Oct;188(4):411-9.

主編：王建波、方呈祥、章志宏。遺傳學(xué)實(shí)驗(yàn)。武漢：武漢大學(xué)出版社，2004

1.《微生物學(xué)》- 利用現(xiàn)代化理念和手段，銳意改革，不斷創(chuàng)新，全面提高

微生物學(xué)教學(xué)水平

2003年獲武漢大學(xué)優(yōu)秀教學(xué)成果 特等獎(jiǎng) (排名第二)

2005年獲湖北省優(yōu)秀教學(xué)成果 一等獎(jiǎng) (排名第二)

2005年獲國(guó)家級(jí)教學(xué)成果 二等獎(jiǎng) (排名第二)

2．《系統(tǒng)微生物學(xué)》

2000年獲武漢大學(xué)研究生課程優(yōu)秀教學(xué)成果獎(jiǎng)