姓名:金雙俠

碩博導(dǎo):博導(dǎo)

職稱(chēng):教授

開(kāi)設(shè)課程:植物生物技術(shù),作物生產(chǎn)實(shí)習(xí),育種學(xué)實(shí)習(xí)

研究方向:目前主要從事棉花生物技術(shù)研發(fā)（基因編輯等）；棉花與害蟲(chóng)互作分子機(jī)制及抗蟲(chóng)相關(guān)基因的克隆和高效表達(dá)載體（葉綠體轉(zhuǎn)化表達(dá)體系）的開(kāi)發(fā)研究等; 高等植物基因組進(jìn)化。

1997-2001年，華中農(nóng)業(yè)大學(xué) 學(xué)士

2001-2006年，華中農(nóng)業(yè)大學(xué) 碩士、博士學(xué)位

2007.10?-2012.4?, 美國(guó)賓夕法尼亞大學(xué)Henry Daniell?教授課題組進(jìn)行博士后研究

2012.5- 至今, 華中農(nóng)業(yè)大學(xué)作物遺傳改良國(guó)家重點(diǎn)實(shí)驗(yàn)室PI, 博導(dǎo)、教授

華中農(nóng)業(yè)大學(xué)植物科學(xué)技術(shù)學(xué)院教授、博導(dǎo)，作物遺傳改良國(guó)家重點(diǎn)實(shí)驗(yàn)室PI， 塔里木大學(xué)“昆侖學(xué)者”特聘教授。

近年來(lái)以第一作者或通訊作者在國(guó)際知名學(xué)術(shù)期刊 GenomeBiology, Advanced Science, Nature Communications, Trends in Plant Science，New Phytologist，Plant Physiology，Plant Biotechnology Journal?等雜志上發(fā)表30多篇植物抗蟲(chóng)基因工程的學(xué)術(shù)文章，其中IF大于6的文章18篇，論文被引用次數(shù)2300多次，H指數(shù)：29。2018年入選?Plant Biotechnology Journal?雜志（IF=8.15）副主編以及Journal of Cotton Research（棉花學(xué)報(bào)英文版）副主編（高級(jí)編輯）；2017年當(dāng)選棉花基礎(chǔ)研究領(lǐng)域權(quán)?[2]威學(xué)術(shù)機(jī)構(gòu)-國(guó)際棉花基因組協(xié)會(huì)（ICGI）共同主席。先后主持國(guó)家自然科學(xué)基金面上項(xiàng)目4項(xiàng)，轉(zhuǎn)基因?qū)ｍ?xiàng)子課題3項(xiàng)，十三五國(guó)家重點(diǎn)研發(fā)專(zhuān)項(xiàng)（子課題）1項(xiàng)，湖北省自然科學(xué)基金重點(diǎn)項(xiàng)目（杰青）1項(xiàng) 。

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1.國(guó)家自然科學(xué)基金 面上項(xiàng)目主持2020-2024十三五國(guó)家重點(diǎn)研發(fā)專(zhuān)項(xiàng) 子課題 主持 2016-2020

3. 轉(zhuǎn)基因?qū)ｍ?xiàng)子課題（3項(xiàng)） 主持 2016-2020

4. 湖北省自然科學(xué)基金重點(diǎn)項(xiàng)目（杰青項(xiàng)目） 主持 ， 2015.1-2016.12

5. 國(guó)家自然科學(xué)基金 面上項(xiàng)目 煙粉虱與棉花互作的分子機(jī)理研究 主持，2014-2017

6. 國(guó)家自然科學(xué)基金 面上項(xiàng)目 植物凝集素基因在棉花中的功能分析, 主持, 2012-2015

7. 新疆建設(shè)兵團(tuán)博士資金項(xiàng)目 轉(zhuǎn)基因抗病蟲(chóng)、抗逆聚合雜交棉新組合選育技術(shù)研究，主持，2007－2009

8. 國(guó)家自然科學(xué)基金 面上項(xiàng)目 棉花外源基因葉綠體轉(zhuǎn)化體系的建立及其應(yīng)用（30771368），主持，2008－2010

9.教育部博士點(diǎn)新教師基金 以gfp基因?yàn)閳?bào)告基因監(jiān)測(cè)轉(zhuǎn)基因棉花花粉漂移（20070504087），主持，2008－2010

10. 國(guó)家自然科學(xué)基金重大國(guó)際合作項(xiàng)目 Development of strong pest-resistance cotton viatransforming plastid and

its application in breeding, 主要參加者，2009－2011

11. 國(guó)家自然科學(xué)基金 利用基因誘捕構(gòu)建棉花功能基因組研究突變?nèi)后w，主要參加，2005-2007

【棉花種質(zhì)創(chuàng)新及強(qiáng)優(yōu)勢(shì)雜交新品種選育與應(yīng)用】 國(guó)家科技進(jìn)步二等獎(jiǎng) 2013年

【棉花體細(xì)胞離體遺傳操作技術(shù)與控制理論】 教育部自然科學(xué)二等獎(jiǎng)

湖北省優(yōu)秀博士學(xué)位論文（第10批）獲獎(jiǎng)?wù)?2008年

湖北省優(yōu)秀本科論文指導(dǎo)獎(jiǎng)，2008年。指導(dǎo)的2007界本科生張碧瑤，其論文：新疆棉花高體細(xì)胞胚胎發(fā)生

能力基因型的篩選，獲得湖北省優(yōu)秀本科學(xué)位論文

“棉花分子育種技術(shù)體系建立與應(yīng)用”獲2008年湖北省技術(shù)發(fā)明二等獎(jiǎng)

獲第十、十一屆湖北省自然科學(xué)優(yōu)秀論文一等獎(jiǎng)2次

1. 超聲波輔助農(nóng)桿菌轉(zhuǎn)化棉花胚芽的方法，專(zhuān)利申請(qǐng)?zhí)枺?00710063650.0

?2. 一種分離棉花葉綠體DNA的方法，專(zhuān)利申請(qǐng)?zhí)枺?00710052665.7

?3.利用苦豆子分離基因SaVP1培育耐高溫?cái)M南芥的方法. 專(zhuān)利號(hào)ZL 201310006089.8

4.利用花花柴KcNHX1 基因培育耐高溫?cái)M南芥的方法 專(zhuān)利申請(qǐng)?zhí)枺?01310160491.1

?5. 利用棉花GhPEPC基因創(chuàng)造棉花高油材料的方法 專(zhuān)利申請(qǐng)?zhí)枺?01510836230.6

?6. 一種提高棉花再生及轉(zhuǎn)化效率的方法及應(yīng)用 專(zhuān)利申請(qǐng)?zhí)?201510836230.6

?7. 一種棉花基因的編輯方法 專(zhuān)利申請(qǐng)?zhí)?2016111884024

8. 利用植物介導(dǎo)的RNAi技術(shù)創(chuàng)造棉花抗中黑盲蝽新種質(zhì)的方法 專(zhuān)利申請(qǐng)?zhí)枺?017102984371

9. 一種DsRED2報(bào)告基因在棉花遺傳改良中的應(yīng)用 專(zhuān)利申請(qǐng)?zhí)?201611113581.5

10. 陸地棉基因組的精準(zhǔn)高效編輯方法 專(zhuān)利申請(qǐng)?zhí)?018115777177

11. 陸地棉基因組的精確高效編輯方法 專(zhuān)利申請(qǐng)?zhí)?201910290886.0

12. 利用植物介導(dǎo)的RNAi創(chuàng)造棉花抗綠盲蝽種質(zhì)的方法? 專(zhuān)利申請(qǐng)?zhí)?2019100115879

?1. Bo Li, Sijia Liang, Muna Alariqi, Fuqiu Wang, Guanying Wang, QiongqiongWang1, Zhongping Xu, Lu Yu, Muhammad Naeem Zafar, Lin Sun, Huan Si, DaojunYuan, Weifeng Guo, Yanqin Wang, Keith Lindsey, Xianlong Zhang*,?Shuangxia Jin*。Theapplication of temperature sensitivity CRISPR/LbCpf1 (LbCas12a) mediated genomeediting in allotetraploid cotton (G. hirsutum) and creation of nontransgenic,gossypol-free cotton.?PlantBiotechnology Journal,?2020. （*通訊作者）（IF: 8.15）

2. Junzhong Shang, Jingpu Tian, Huihui Cheng, Qiaomu Yan, Lai Li, AbbasJamal, Zhongping Xu, Lin Xiang, Christopher A Saski,?Shuangxia Jin*,?Kaige Zhao*, Xiuqun Liu*, Longqing Chen*.The chromosome-level wintersweet (Chimonanthus praecox) genome provides insights into floral scent biosynthesis and flowering in winter.?Genome Biology,?2020?（*通訊作者）（IF: 10.8）

3. Qiuyue Ma, Tianlin Sun, Shushun Li, Jing Wen, LuZhu, Tongming Yin, Kunyuan Yan, Xiao Xu, Shuxian Li, Jianfeng Mao, Ya-nan Wang,?Shuangxia Jin, Xing Zhao*, Qianzhong Li* . The Acer truncatum genome provides insights into the nervonic acid biosynthesis.?Plant Journal, 2020.?(IF: 6.14)

4. Qiongqiong Wang, Muna Alariqi, Fuqiu Wang, Bo Li, Xiao Ding, HangpingRui, Yajun Li, Jianying Li, Zhongping Xu, Lei Qin, Lin Sun, Jianying Li, JiaweiZou, Keith Lindsey, Xianlong Zhang,?ShuangxiaJin*.?The application of a heat-inducible CRISPR/Cas12b (C2c1) genome editing system in tetraploid cotton (G.hirsutum) plants.?PlantBiotechnology Journal,2020 （*通訊作者）（IF: 8.15）

5.?Hakim Manghwar, Xianlong Zhang*,?ShuangxiaJin*. Strategies to overcome off-target effects by CRISPR/Cas system (2020).?Advanced Science. 2020, 7(6):1902312 （*通訊作者）(IF: 15.8)

6.?Hakim Manghwar, Xianlong Zhang*,?ShuangxiaJin*. CRISPR/Cas system: its recent advances and future prospect in genome editing of plant species (2019),?Trends in Plant Science. 2019, 24(12):1102-1125（*通訊作者）(IF: 14.4)

7.Lisong Hu, Zhongping Xu, et al., Chaoyun Hao* &?Shuangxia Jin*.?The chromosome-scale reference genome of black pepper (Piper nigrum) provides further insight into piperine biosynthesis.?Nature Communications,2019, 10:4702（*通訊作者）（IF: 12.1）

8.Lei Qin, Jianying Li, Qiongqiong Wang, Zhongping Xu, Lin Sun, Muna Alariqi, HakimManghwar, Guanyin Wang, Bo Li, Xiao Ding, Hangping Rui, HuimeiHuang, Tianliang Lu , Keith Lindsey，HenryDaniell, Xianlong Zhang,?Shuangxia Jin*. High Efficient and Precise Base Editing of C·G to T·A in the Allotetraploid Cotton (Gossypium hirsutum) Genome Using a Modified CRISPR/Cas9 System.?Plant Biotechnology Journal,?2020, 18(1):45-56 （*通訊作者）(IF: 8.15)

9.Bo Li, Hangping Rui, Yajun Li, Qiongqiong Wang, Muna Alariqi, Lei Qin, Lin Sun, Xiao Ding, Fuqiu Wang, Jiawei Zou,YanqingWang, Daojun Yuan, Xianlong Zhang?ShuangxiaJin?*. Robust CRISPR/Cpf1(Cas12a) mediated genome editing in allotetraploid cotton (G.hirsutum).?Plant Biotechnology Journal,?2019, 17(10):1862-1864（*通訊作者）(IF: 8.15)

10. Maojun Wang, Lili Tu, DaojunYuan, De Zhu, Chao Shen, Jianying Li, Fuyan Liu, Liuling Pei, Pengcheng Wang,Guannan Zhao, Zhengxiu Ye, Hui Huang, Feilin Yan, Yizan Ma, Lin Zhang, Min Liu,Jiaqi You, Yicheng Yang, Zhenping Liu, Fan Huang, Baoqi Li, Ping Qiu, QinghuaZhang, Longfu Zhu,?Shuangxia Jin,?Xiyan Yang, Ling Min, Guoliang Li,Ling-Ling Chen, Hongkun Zheng, Keith Lindsey, Zhongxu Lin, Joshua A. Udall& Xianlong Zhang. Reference genome sequences of two cultivated allotetraploid cottons,?Gossypium hirsutum?and?Gossypium barbadense.?Nature Genetics,?2019, 51(2): 224-229（IF:27.6）

11.Li Jianying; ManghwarHakim; Sun, Lin; Wang, Pengcheng; Wang, Guanying; Sheng, Hanyan; Zhang, Jie; Liu, Hao; Qin, Lei; Rui, Hangping; Li, Bo, Lindsey, Keith, Daniell, Henry,Jin, Shuangxia*; Zhang, Xianlong.Whole genome sequencing reveals rare off-target mutations and considerable inherent genetic or/and somaclonal variations in CRISPR-Cas9-edited cotton plants.?Plant Biotechnology Journal,2019, 17, 858-868 （*通訊作者）(IF: 8.15)

12. Jianying Li, Maojun Wang, YajunLi, Qinghua Zhang, Keith Lindsey, Henry Daniell,?Shuangxia Jin*,Xianlong Zhang. Multi-omics analyses reveal epigenomics basis for cotton somatic embryogenesis through successive regeneration acclimation (SRA)process,?Plant Biotechnology Journal,?2019, 17, 435u2013450（*通訊作者）?( IF: 8.15)

13. Hu Q, Min L, Yang X,?Jin S,Zhang L, Li Y, Ma Y, Qi X, Li D, Liu H, Lindsey K, Zhu L, Zhang X. LaccaseGhLac1 modulates broad-spectrum biotic stress tolerance via DAMP-triggered immunity.?Plant Physiology, 2018, 176(2):1808-1823.?(IF: 6.9)

14. Wang, Pengcheng; Zhang, Jun;Sun, Lin; Ma, Yizan; Xu, Jiao; Liang, Sijia; Deng, Jinwu; Tan, Jiafu; Zhang,Qing; Tu, Lili; Daniell, Henry;?Jin, Shuangxia*; Zhang, Xianlong*. High efficient multi-sites genome editing in allotetraploid cotton (Gossypiumhirsutum) using CRISPR/Cas9 system,Plant Biotechnology Journal,?2018,16, 137-150（*通訊作者）(IF: 8.15)

15. Luo, Jing; Liang, Sijia; Li,Jianying; Xu, Zhongping; Li, Lun; Zhu, Bangqin; Li, Zhe; Lei, Chaoliang;Lindsey, Keith; Chen, Lizhen*;?Jin, Shuangxia*; Zhang, Xianlong. A transgenic strategy for controlling plant bugs (Adelphocoris suturalis) through expression of double- stranded RNA (dsRNA) homologous to Fatty acyl-CoA reductase (FAR) in cotton.?New Phytologist,?2017,215,1173-1185（*通訊作者）?( IF: 8.5)

16. Maojun Wang, Lili Tu, Min Lin,Zhongxu Lin, Pengcheng Wang, Qingyong Yang, Zhengxiu Ye, Chao Shen, JianyingLi, Lin Zhang, Xiaolin Zhou, Xinhui Nie, Zhonghua Li, Kai Guo, Yizan Ma, CongHuang,?Shuangxia Jin,?Longfu Zhu, Xiyan Yang, Ling Min, Daojun Yuan,Qinghua Zhang, Keith Lindsey & Xianlong Zhang. Asymmetric subgenome selection and cis-regulatory divergence during cotton domestication,?Nature Genetics,?2017,49(4):579-587 （IF: 27）

17. Jianying Li#, Lizhen Zhu#, Joe Hull, SijiaLiang, Henry Daniell,?Shuangxia Jin*,?Xianlong Zhang. Transcriptome analysisreveals a comprehensive insect resistance response mechanism in cotton to infestation by the phloem feeding insect Bemisia tabaci (whitefly).?PlantBiotechnology Journal,?2016,14,1956-1975 (SCI, IF:6.3)（通訊作者）(IF: 8.15)

18.?Shuangxia Jinand Henry Daniell.The Engineered Chloroplast Genome Just Got Smarter.?Trendsin Plant Science, 2015，20(10):622-640 （IF:14.4）

19.?Jin Shuanxia,Singh, Dolendro,Li Lebin,Zhang, Xianlong and Daniell, Henry. Engineered chloroplast dsRNA silences cytochrome p450 monooxygenase, V-ATPase and chitinsynthases genes in the insect gut and disrupts Helicoverpa armigera larval development and pupation.?Plant Biotechnology Journal, 2015,13(3), 435-446. (IF:8.15)

20.?Shuangxia Jinand Henry Daniell. Expression of γ-tocopherol methyltransferase in chloroplasts results in massive proliferation of the inner envelope membrane and decreases susceptibility tosalt and metal-induced oxidative stress by reducing reactive oxygen species.?Plant Biotechnology Journal,?2014 (12),1274-1285 . (IF:8.15)

21.?Shuangxia Jin,Xianlong Zhang1, Henry Daniell. Pinellia ternata agglutinin expression in chloroplasts confers broad spectrum resistance against aphid, whitefly,lepidopteran insects, bacterial and viral pathogens.?Plant Biotechnology Journal?2012,10(3):313-327 (Cover Story, IF 8.15 ).

22.?Shuangxia Jin,Anderson Kanagaraj, Dheeraj Verma, Theo Lange, Henry Daniell.Release of Hormones from Conjugates: Chloroplast Expression of ?-glucosidase Results in Elevated Phytohormone Levels Associated with Significant Increase in Biomass and Protection from Aphids or Whiteflies Conferred by Sucrose Esters.Plant Physiology?,2011,155,222-235. (IF:6.9).