個(gè)人經(jīng)歷
1989年畢業(yè)于北京大學(xué)生物系 獲學(xué)士學(xué)位
1997年在美國(guó)University of Wisconsin-Madison 獲博士學(xué)位
1997年至2001年在美國(guó)The Scripps Research Institute 博士后
研究方向
蛋白質(zhì)結(jié)構(gòu)與功能關(guān)系的核磁共振譜學(xué)研究
蛋白質(zhì)的結(jié)構(gòu)基因組學(xué)研究
疾病的代謝組學(xué)研究
利用核磁共振（NMR）技術(shù)，結(jié)合其它的生化及分子生物學(xué)研究技術(shù)，研究生物大分子結(jié)構(gòu)、相互作用，以期揭示其結(jié)構(gòu)與功能關(guān)系，揭示其作用的分子機(jī)理。主要的研究對(duì)象包括抑癌基因HREV家族的蛋白，SARS主蛋白酶，植物谷氧還蛋白（Grx）。
主要論文
- Y. Feng, N. Rouhier, J. P. Jacquot, B. Xia “1H, 15N, and 13C resonance assignments of reduced glutaredoxin C1 from Populus tremula x tremuloides”, J. Biomol. NMR 31，263-264 (2005).P Ding. Kirsty A. McFarland. S Jin. Grace Tong.B Duan. Ally Yang. Timothy R. Hughes. J Liu. Simon L. Dove, William Wiley Navarre and B Xia.A Novel AT-Rich DNA Recognition Mechanism for Bacterial Xenogeneic Silencer MvaTPLOS Pathogens | DOI:10.1371/journal.ppat.1004967 June 11, 2015H. Wei, L. Wang, X. Ren, W. Yu, J. Lin, C. Jin, andB. Xia*“Structural and Functional Characterization of Tumor Suppressors TIG3 and H-REV107”FEBS Lett.589:1179-86 (2015).P. Ding, K. A. McFarland, S. Jin, G. Tong, B. Duan, A. Yang,T. R. Hughes, J. Liu,S. L. Dove*,W. W. Navarre*,B. Xia*“A Novel AT-rich DNA Recognition Mechanismfor Bacterial Xenogeneic Silencer MvaT”.PLOS Pathog.11:e1004967 (2015)L. Wang, Y. Li, J. P. Jacquot, N. Rouhier,B. Xia*“Characterization of poplar GrxS14 in different structural forms”,Protein Cell5: 329-33 (2014)M. Li, X. Ma, Y. H. Chiang, K. A. Yadeta, P. Ding, L. Dong, Y. Zhao, X. Li, Y. Yu, L. Zhang, Q. H. Shen,B. Xia, G. Coaker, D. Liu, J.-M. Zhou“Proline Isomerization of the Immune Receptor-Interacting Protein RIN4 by a Cyclophilin Inhibits Effector-Triggered Immunity in Arabidopsis”,Cell Host Microbe16: 473-83 (2014).Z. Ming, W. Wang, Y. Xie, P. Ding, Y. Chen, D. Jin, Y. Sun,B. Xia, L. Yan, Z. Lou“Crystal structure of the novel di-nucleotide cyclase from Vibrio cholerae (DncV) responsible for synthesizing a hybrid cyclic GMP-AMP”,Cell Res.24: 1270-3 (2014).
