個人簡介
陳帥,在Nature Cell Biology等SCI雜志上發(fā)表第一作者及通訊作者論文十余篇,并獲得國家自然科學基金、國家重點基礎研究發(fā)展計劃(973)、重大新藥創(chuàng)制等經費的資助。主要研究方向是腫瘤微環(huán)境調控及靶向治療。
代表論文
1、Chen S, Bohrer L, Rai A, Pan Y, Gan L, Zhou X, Bagchi A, Simon JA, Huang H. Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2. Nat Cell Biol 2010 Nov; 12(11):1108-14. (selected by Faculty of 1000)
2、Wang L#, Zeng X#, Chen S#, Ding L, Zhong J, Zhao JC, Sarver A, Koller A, Zhi J, Ma Y, Yu J, Chen J, Huang H. BRCA1 is a negative modulator of the PRC2 complex. EMBO J. 2013 May 29;32(11):1584-97. (#并列第一作者;selected by Faculty of 1000)
3、Chen S, Sheng C, Liu D, Yao C, Gao S, Song L, Jiang W, Li J, Huang W. Enhancer of zeste homolog 2 is a negative regulator of mitochondria-mediated innate immune responses. J Immunol. 2013 Sep 1;191(5):2614-23.
4、Ding L#, Chen S#, Liu P, Pan Y, Zhong J, Regan KM, Wang L, Yu C, Rizzardi T, Cheng L, Zhang J, Schmechel SC, Cheville JC, van Deursen J, Tindall DJ, Huang H. CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy. Cancer Res. 2014 Apr 1;74(7):2050-61.(#并列第一作者)