基本內(nèi)容
馮波,教授;主要從事生物化學、免疫分析等方面的科研教學工作;近年來主持國家自然科學基金等課題5項,獲國家授權(quán)發(fā)明專利2項,在國內(nèi)外學術(shù)期刊上發(fā)表論文20余篇;目前應邀擔任了國家自然科學基金委生命科學部通訊評議人,ACS Applied Materials & Interfaces等國際學術(shù)期刊審稿人,并入選湘潭大學首屆“青年拔尖人才”工程。
研究方向
生物大分子的界面吸附及其免疫學特性分析。
科研項目
1)國家自然科學基金面上項目:SPA-IgG復合體分子內(nèi)的蛋白質(zhì)多靶標并行檢測(編號:31270988),起止日期:2013.01~2016.12.
2)國家自然科學基金青年項目:親和標簽肽引導的SPA-IgG組裝體導向固定構(gòu)建三維固相抗體(編號:21105085),起止日期:2012.01~2014.12.
3)中國博士后科學基金:SPA-IgG超分子復合體構(gòu)筑三維抗體膜(編號:2014M562118),起止日期:2014.09~2016.12.
4)湖南省自然科學基金面上項目:差異化修飾葡萄球菌A蛋白構(gòu)筑自組裝三維抗體膜(編號:2015JJ2133),起止日期:2015.01~2017.12.
5)湖南省教育廳優(yōu)秀青年項目:親和標簽肽單鏈融合抗體導向固定探針檢測HCV抗原(編號:13B120),起止日期:2013.09~2015.12.
代表性學術(shù)論文
1)3D antibody immobilization on a planar matrix surface. Biosensors and Bioelectronics, 2011, 28: 91-96.
2) Effects of heavy metal wastewater on the anoxic/aerobic-membrane bioreactor bioprocess and membrane fouling. Bioresource Technology, 2013, 142: 32-38.
3)Facile synthesis of boron and nitride doped MoS2 nanosheets as fluorescence probes for ultrafast, sensitive, and label-free detection of Hg2+. Analyst, 2015, 140: 4654-4661.
4)Synthesis of fluorescent BCN hybrid nanosheets: A highly efficient fluorosensor for rapid, simple, sensitive Ag+ detection. RSC Advances, 2015, 5: 52452-52458.
5)A new method for multilayered, site-directed immobilization of antibody on polystyrene surface. Biochemical and Biophysical Research Communications, 2014, 450: 429-432.
6)Site-oriented immobilization of fusion antigen directed by an affinity ligand, and its validation in an immunoassay. Surface and Interface Analysis, 2011, 43: 1304-1310.
7) A novel affinity ligand for polystyrene surface from a phage display random library and its application in anti-HIV-1 ELISA system. Biologicals, 2009, 37: 48-54.
8)How an improved immunoassay sensitivity can be achieved by gamma irradiation: modification, application and characterization of polystyrene surface for anti HIV-1 ELISA. Journal of Immunoassay & Immunochemistry, 2009, 30: 457-466.
9)Quartz crystal microbalance study of kinetics and thermodynamics of IgG adsorption on the polystyrene surface. Surface Review and Letters, 2015, 22: 1550026, 1-8.
10)Research progress on site-oriented and three-dimensional immobilization of protein. Molecular Biology, 2015, 49: 1-20.
11)Practical detection for simultaneous analysis of multiple antigens with Staphylococcal protein A as an intermediate. Analytical Methods, 2015, 7: 9018-9025.
授權(quán)專利
1)一種能與聚苯乙烯親和結(jié)合的標簽肽及其用于制備酶聯(lián)免疫固相抗原的方法,專利號:ZL201010274128.9
2)一種硼和氮雙摻雜的二硫化鉬熒光納米材料的制備方法,專利號:ZL201410753247.0