個人簡介
博士，研究員，博士生導師。
2006年6月畢業(yè)于美國加州大學，獲得博士學位。2006年7月至2013年，先后在美國美國加州大學與美國西奈山伊坎醫(yī)學院完成博士后工作。2014年進入中國科學院生態(tài)環(huán)境研究中心-環(huán)境化學與生態(tài)毒理學國家重點實驗室工作，是中心引進的第一位外籍研究員。費凡研究員在Myc/Max后轉錄修飾在腫瘤發(fā)生的效應研究中取得了出色的研究成果。目前已發(fā)表Nature、PNAS與Cell Research等多篇高水平的學術論文。
研究領域
干細胞毒理學，環(huán)境科學（環(huán)境與健康）。
代表性論文
1.Faiola F, Yin N, Yao X, Jiang G. The Rise of Stem Cell Toxicology.Environ Sci Technol.2015 May 19;49（10）:5847-8
2.Faiola, F., Wu, Y.T., Pan, S., Zhang, K., Farina, A., &Martinez, E.Max is acetylated by p300 at several nuclear localization residues.Biochem J.403,397-407 （2007）.
3.Faiola, F., Liu, X., Lo, S., Pan, S., Zhang, K., Lymar, E., Farina, A. &Martinez, E.Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription.Mol Cell Biol.23,10220-34 （2005）.
4.Faiola, F., Saunders, A., Dang, B. & Wang, J. An improved in vivo biotinylation strategy combined with Flag and antibody based approaches for affinity purification of protein complexes in mouse embryonic stem cells.Methods Mol Biol.,in press.
5.Saunders, A.,Faiola, F. & Wang, J. Concise review: pursuing self-renewal and pluripotency with the stem cell factor nanog.Stem Cells31（7）, 1227-36 （2013）.
6.Fidalgo, M.,Faiola, F., Pereira, C.F., Ding, J., Saunders, A., Gingold, J., Schaniel, C., Lemischka, I., Silva, J.C. & Wang, J. Zfp281 mediates Nanogautorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming.ProcNatlAcadSci U.S.A.109（40）. 16202-7 （2012）.
7.Wang, Y.L.,Faiola, F. & Martinez, E. Purification of multiprotein histone acetyltransferase complexes.Methods Mol Biol.809, 427-43 （2012）.
8.Ding, J., Xu, H.,Faiola, F., Mau2019ayan, A. & Wang, J. Oct4 links multiple epigenetic pathways to the pluripotency network.Cell Res.22（1）, 155-67 （2011）.
9.Wang, Y.L.,Faiola, F., Xu, M., Pan, S. & Martinez, E. Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein.J Biol Chem.283, 33808-15 （2008）. （Selected for Faculty of 1000 Biology）.
10.Zhang, K.,Faiola, F.&Martinez, E.Six lysine residues on c-Myc are direct substrates for acetylation by p300.BiochemBiophys Res Commun.336, 274-80 （2005）.
11.Farina, A.,Faiola, F. &Martinez E.Reconstitution of an E box-binding Myc:Max complex with recombinant full-length proteins expressed in Escherichia coli.Protein Expr Purif.34,215-22（2004）.
12.Marconi, W.,Faiola, F. &Piozzi, A.Catalytic activity of immobilized fumarase.Journal of MolecularCatalysis. B, Enzymatic1-3, 93-99 （2001）.
13.Costa, Y., Ding, J., Theunissen, T.W.,Faiola, F., Hore, T.A., Shliaha, P.V., Fidalgo, M., Saunders, A., Lawrance, M., Dietmann, S., Das, S., Levasseur, D.N., Li, Z., Xu, M., Reik, W., Silva, J.C.R. & Wang, J. NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.Nature495（7441）, 370-4 （2013）.
專家類別：
研究員
