科研方向
主研方向： 主要研究方向集中在金屬有機(jī)化學(xué)及有機(jī)合成化學(xué)。設(shè)計(jì)合成新型的手性配體，以這些配體與主族或過(guò)渡金屬元素合成手性催化劑，并對(duì)它們誘導(dǎo)的不對(duì)稱(chēng)反應(yīng)進(jìn)行研究；探索新型的不對(duì)稱(chēng)有機(jī)反應(yīng)，拓展不對(duì)稱(chēng)合成方法學(xué)研究；把高選擇得不對(duì)稱(chēng)反應(yīng)應(yīng)用與手性藥物中間體及手性藥物的全合成，拓展不對(duì)稱(chēng)合成方法的應(yīng)用。
在研項(xiàng)目： （1）國(guó)家自然科學(xué)基金項(xiàng)目“手性墻配體的合成及其金屬配合物催化的不對(duì)稱(chēng)反應(yīng)研究”。（2）國(guó)家自然科學(xué)基金重點(diǎn)項(xiàng)目“導(dǎo)向有機(jī)合成的雜原子化學(xué)”中的子課題“手性仿黃素衍生物的合成及其催化的不對(duì)稱(chēng)反應(yīng)研究”。（3）金屬有機(jī)化學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室（中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所）開(kāi)放課題“手性鎵銦金屬有機(jī)化合物的合成及其導(dǎo)引的不對(duì)稱(chēng)反應(yīng)研究”。
已發(fā)表論文
發(fā)表論文：
1. Minghua Yang, Chengjian Zhu, Fang Yuan, Yijun Huang, Yi Pan, “Enantioselective ring opening reaction of meso epoxides with ArSeH catalyzed by heterometallic Ti-Ga-Salen system” Org. Lett., 2005, 7, 1927.
2. Jiangtao Sun, Chengjian Zhu, Zhenya Dai, Minghua Yang, Yi Pan, Hongwen Hu, “Efficient Asymmetric Oxidation of Sulfides and Kinetic Resolution of Sulfoxides Catalyzed by Vanadium Salan System” J. Org. Chem., 2004, 67, 8500.
3. Chengjian Zhu, Fang Yuan, Weijin Gu, Yi Pan, “The First Example of Enantioselective Isocyanosilylation of meso Epoxides with TMSCN Catalyzed by Novel Chiral Organogallium and Indium Complexes” Chem. Commun., 2003, 692.
4. R. Rather, S. V. Lindeman, C. J. Zhu, T. Mori, P. R. Schleyer, J. K. Kochi, “Steric Hindrance as a Mechanistic Probe for Olefin Reactivity: Variability of the Hydrogenic Canopy over the Isomeric Adamantylideneadamantane/Sesquihomoadamantene Pair (A Combined Experimental and Theoretical Study)” J. Org. Chem., 2002, 67, 5106. 5. Jay K. Kochi, Rajendre Rathore, Chengjian Zhu, S. V. Lindeman, "Structure Characterization of Novel Olefinic Cation Radicals. X-ray Crystallographic Cvidence of Hyperconjugation." Angew. Chem. Int. Ed. Engl., 2000, 39, 3671.
