人物經(jīng)歷
?學(xué)歷簡介：
?1988中國科技大學(xué)博士1998美國康涅狄格州大學(xué)
工作經(jīng)歷：
1998年?至?2001年美國費(fèi)城Fox?Chase癌癥研究中心?做小鼠β細(xì)胞的研究2001年?至?2005年美國國立衛(wèi)生院?研究人胰腺β細(xì)胞的發(fā)育2005年?至?現(xiàn)在汕頭大學(xué)多學(xué)科研究中心?教授
擔(dān)任課程
基礎(chǔ)分子生物學(xué)
生命科學(xué)前沿進(jìn)展
科研方向
胰腺Beta細(xì)胞的發(fā)育、糖尿病的防治、細(xì)胞衰老、分子治療、合成生物學(xué)
承擔(dān)項(xiàng)目
[?1?]?國家自然科學(xué)基金面上項(xiàng)目?新型非病毒類整合性載體的構(gòu)建及在1型糖尿病防治中的應(yīng)用；(編號：81172894)，
[?2?]?國家自然科學(xué)基金面上項(xiàng)目?慢病毒載體在成年胰島產(chǎn)生機(jī)制研究新策略中的應(yīng)用；(編號：30971665)，
著述成果
[?1?]?Shui-li?Zhang,?De-jin?Zheng,?Wen-zhu?Fan,?Dai-xu?Wei,?Si-wu?Peng,?Mi-mi?Tang,?Guo-Qiang?Chen,?Chi-ju?Wei；Transient?embolization?with?microspheres?of?polyhydroxyalkanoate?renders?efficient?adenoviral?transduction?of?pancreatic?capillary?in?vivo.；Journal?of?Gene?Medicine?14:?530u2013539；[?2?]?Hong-ming?Li,?Mei?Zhang,?Di-zheng?Li,?Sheng-tao?Xu,?Lin-yun?Zhu,?Si-wu?Peng,?Guo-qiang?Chen,?Pamela?M.?Martin,?Vadivel?Ganapathy,?Chi-ju?Wei；Nicotinic?Acid?Inhibits?Glucose?Stimulated?Insulin?Secretion?Via?The?G-Protein?Coupled?Receptor?PUMA-G?on?Murine?Islet?beta-Cells；Pancreas.?40:615-621；[?3?]?Mi-mi?Tang,?Qin-e?Zhu,?Wen-zhu?Fan,?Shui-li?Zhang,?Di-zheng?Li,?Li-zhong?Liu,?Miao?Chen,?Mei?Zhang,?Jing?Zhou,?Chi-ju?Wei；Intra-Arterial?Targeted?Islet-Specific?Expression?of?Sirt1?Protects?Beta?Cells?from?Streptozotocin?Induced?Apoptosis?in?Mice.；Molecular?Therapy?19:60-66；[?4?]?Si-wu?Peng,?Lin-yun?Zhu,?Miao?Chen,?Mei?Zhang,?Di-zheng?Li,?Yu-cai?Fu,?Shen-ren?Chen,?Chi-ju?Wei；Heterogeneity?in?mitotic?activity?and?telomere?length?implies?an?important?role?of?young?islets?in?the?maintenance?of?islet?mass?in?the?adult?pancreas；Endocrinology?150?(7):?3058-3066；[?5?]?Xiao-Di?Yang,?Hong-Ming?Li,?Miao?Chen,?Xiang-Hui?Zou,?Lin-Yun?Zhu,?Guo-Qiang?Chen,?Chiju?Wei；Enhanced?Insulin?Production?from?Murine?Islet?Beta?Cells?Incubated?on?Poly?(3-Hydroxybutyrate-co-3-Hydroxyhexanoate)；Journal?of?Biomedical?Materials?Research?Part?A?92A?(2):548-555；[?6?]?Chiju?Wei,?Richard?Zeff,?and?Irving?Goldscheider.?2000；Murine?pro-B?cells?require?IL-7?and?its?receptor?complex?to?up-regulate?IL-7R,?TdT?and?C?m?expression；J.?Immunology?164:161；[?7?]?Chiju?Wei,?Laijun?Lai,?and?Irving?Goldscheider.?2002；PPBSF?is?essential?for?the?up-regulation?of?IL-7R?a?on?pro-B?cells?from?IL-7?KO?mice；Journal?of?Interferon?and?Cytokine?Research?22(7):823；[?8?]?Richard?R.?Hardy?,?Chiju?Wei,?and?Kyoko?Hayakawa.?2004；Selection?during?development?of?VH11+?B?cells:?a?model?for?natural?autoantibody-producing?CD5+?B?cells；Immunol.?Rev.?197:60-74；[?9?]?Marvin?C.?Gershengorn,?Anandwardhan?A.?Hardikar,?Chiju?Wei,?Elizabeth?Geras-Raaka,?Bernice?Marcus-Samuels,?Bruce?M.?Raaka.?2004；Epithelial-to-Mesenchymal?Transition?Generates?Proliferative?Human?Islet?Precursor?Cells；Sciences?306(5705):2261-4；[?10?]?Chiju?Wei,?Elizabeth?Geras-Raaka,?Bernice?Samuels,?Yoram?Oron?and?Marvin?C.?Gershengorn?.?2005；Trypsin?and?Thrombin?Accelerate?Aggregation?of?Human?Endocrine?Pancreas?Precursor?Cells；Accepted?to?Journal?of?Cellular?Physiology。
