個人簡介
孟鳳華,1995年大連理工大學(xué)本科畢業(yè),1998年長春應(yīng)用化學(xué)研究所獲碩士學(xué)位,2003年荷蘭屯特大學(xué)(University of Twente)獲博士學(xué)位,2005-07年荷蘭屯特大學(xué)生物醫(yī)學(xué)技術(shù)研究所博士后。2007年受聘蘇州大學(xué)副教授,碩士生導(dǎo)師,2010年為教授,為蘇州大學(xué)生物醫(yī)用高分子材料實(shí)驗(yàn)室研究骨干。現(xiàn)主持一項(xiàng)國家自然科學(xué)基金及一項(xiàng)教育部留學(xué)歸國人員啟動基金。在國際主流期刊如Angew. Chem.-Int. Edit., Biomaterials, J. Control. Release, Macromolecules, Biomacromolecules等上發(fā)表論文四十多篇,被引用約850次。已申請中國專利7項(xiàng)(3項(xiàng)授權(quán)),國際專利兩項(xiàng)。已受請自2012年起擔(dān)任Bentham Science Publishers的期刊“Current Pharmaceutical Design”(現(xiàn)代藥物設(shè)計(jì))的編委(Editorial Board as an Executive Guest Editor)。連續(xù)兩年獲得2009、2010年中國百篇最具影響國際學(xué)術(shù)論文。
研究領(lǐng)域
智能型生物可降解高分子納米載體(囊泡和膠束)、蛋白質(zhì)的控制釋放、癌癥的診斷及靶向治療
代表性論文
PolymersomesSpanningfromNanotoMicroScales:AdvancedVehiclesforControlledDrugDeliveryandRobustVesiclesforVirusandCell-Mimicking,,andZ.Y.Zhong*,,2,1533.(InvitedPerspective)
a-AminoAcidContainingDegradablePolymersasFunctionalBiomaterials:RationalDesign,SyntheticPathwayandBiomedicalApplications,H.L.Sun,,A.A.Dias,M.Hendriks,J.Feijen,andZ.Y.Zhong*,,12,1937.
Folate-ConjugatedCrosslinkedBiodegradableMicellesforReceptor-MediatedDeliveryofPaclitaxel,J.Xiong,,C.Wang,R.Cheng,Z.Liu,andZ.Y.Zhong*,,21,5786.(IF5.099)
Thehighlyefficientdeliveryofexogenousproteinsintocellsmediatedbybiodegradablechimaericpolymersomes,G.J.Liu,S.B.Ma,S.K.Li,R.Cheng,H.Y.Liu,Z.Y.Zhong*,,31,7575.(IF7.882)
Shell-sheddablemicellesbasedondextran-ss-poly(e-caprolactone)diblockcopolymerforefficientintracellularreleaseofdoxorubicin,H.L.Sun,,B.N.Guo,X.Q.Li,R.Cheng,H.Y.Liu,Z.Y.Zhong*,,11,848(IF5.325)
pH-SensitiveDegradablePolymersomesforTriggeredReleaseofAnticancerDrugs:aComparativeStudywithMicelles,W.Chen,,R.Cheng,Z.Y.Zhong*,,142,40.(IF7.164)
VersatileSynthesisofFunctionalBiodegradablePolymersbyCombiningRing-OpeningPolymerizationandPostpolymerizationModificationviaMichael-TypeAdditionReaction,W.Chen,H.C.Yang,R.Wang,R.Cheng,,W.X.Wei,Z.Y.Zhong*,,43,201(IF4.837)
ReversiblyStabilizedMultifunctionalDextranNanoparticlesEfficientlyDeliverDoxorubicinintotheNucleiofCancerCells,Y.L.Li,L.Zhu,Z.Z.Liu,R.Cheng,,J.H.Cui,S.J.Ji,Z.Y.Zhong*,9,48,9914.(IF12.730)
Biodegradablemicelleswithsheddablepoly(ethyleneglycol)shellsfortriggeredintracellularreleaseofdoxorubicin,H.L.Sun,B.N.Guo,R.Cheng,,H.Y.Liu,Z.Y.Zhong*,,30:6358.(IF7.882)
pH-ResponsiveBiodegradableMicellesBasedonAcid-LabilePolycarbonateHydrophobe:SynthesisandTriggeredDrugRelease,W.Chen,F.H.Meng,F.Li,S.-J.Ji,,,10:1727.(IF5.325)
Reversiblycrosslinkedtemperature-responsivenano-sizedpolymersomes:synthesisandtriggereddrugrelease,H.F.Xu,,Z.Y.Zhong*,,19:4183.(IF5.099)
Reduction-SensitivePolymersandBioconjugatesforBiomedicalApplications,,W.E.Hennink,Z.Y.Zhong*,,30:2180.(IF7.882).
Stimuli-responsivepolymersomesforprogrammeddrugdelivery.,Z.Y.Zhong*,J.Feijen,,10:197.(IF5.325).
14.Biodegradablepolymersomesasabasisforartificialcells:encapsulation,releaseandtargeting,,G.H.M.Engbers,J.Feijen,.,,101:187.(IF7.164)