姓名: 朱墨桃

性別: 女

職務(wù): 無(wú)

職稱: 副研究員

通訊地址: 北京市海淀區(qū)中關(guān)村北一條11號(hào)

朱墨桃，國(guó)家納米科學(xué)中心副研究員。2004年畢業(yè)于北京大學(xué)藥學(xué)專業(yè)，獲理學(xué)學(xué)士學(xué)位；2009年畢業(yè)于中國(guó)科學(xué)院高能物理研究所，獲生物無(wú)機(jī)化學(xué)博士學(xué)位，師從趙宇亮研究員；2009年受聘于國(guó)家納米科學(xué)中心，現(xiàn)任副研究員。目前已在SCI權(quán)威雜志發(fā)表文章20余篇。

1) 納米材料理化特性對(duì)其生物安全的影響規(guī)律及分子機(jī)制研究;

2)改造天然膜泡納米結(jié)構(gòu)用于抗腫瘤治療;

3) 納米材料在體內(nèi)及細(xì)胞水平的轉(zhuǎn)運(yùn)及代謝行為研究。

1．納米生物安全性研究

2．抗腫瘤納米技術(shù)研究

1. Motao Zhu, Guangjun Nie, Andre Nel*, Yuliang Zhao*. Physicochemical Properties Determine Nanomaterial Cellular Uptake, Transport, and Fate. Acc. Chem

2. Motao Zhu, Yiye Li, Jian Shi, Weiyue Feng, Guangjun Nie*, and Yuliang Zhao*. Exosomes as extrapulmonary signaling conveyors for nanoparticle-induced systemic immune activation

3. Motao Zhu, Xin Tian, Xiao Song, Yanhua Tian, Yuliang Zhao, Guangjun Nie*. Nanoparticle-induced exosomes target antigen-presenting cells to initiate Th1-type immune activation

4. Motao Zhu, Sarah Perrett, Guangjun Nie*. Understanding the Particokinetics of Engineered Nanomaterials for Safe and Effective Therapeutic Applications. Small

5. Xin Tian1, Motao Zhu1 (co-first author), Yanhua Tian, Ramm Grant, Yuliang Zhao*, Guangjun Nie*. A membrane vesicle-based dual vaccine against melanoma and Lewis lung carcinoma. Biomaterials

6. Motao Zhu, Bing Wang, Yun Wang; Lan Yuan, Huajian Wang, Meng Wang, Hong Ouyang, Zhifang Chai, Weiyue Feng*, Yuliang Zhao. Endothelial dysfunction and inflammation induced by iron oxide nanoparticle exposure: Risk factors for early atherosclerosis. Toxicol

7. Motao Zhu, Weiyue Feng, Yun Wang, Bing Wang, Meng Wang, Hong Ouyang，Yuliang Zhao, Zhifang Chai. Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicol. Sci

8. Motao Zhu, Weiyue Feng, Bing Wang, Tiancheng Wang, Yiqun Gu, Meng Wang, Yun Wang, Hong Ouyang, Yuliang Zhao, Zhifang Chai. Comparative study of pulmonary responses to nano- and submicron-sized ferric oxide in rats

9. Motao Zhu, Yun Wang, Weiyue Feng, Bing Wang, Meng Wang, Hong Ouyang，Zhifang Chai. Oxidative Stress and Apoptosis Induced by Iron Oxide Nanoparticles in Cultured Huaman Umbilical Endothelial Cells. J. Nanosci. Nanotechnol

10. Xin Tian, Motao Zhu, Guangjun Nie*. How can nanotechnology help membrane vesicle-based cancer immunotherapy development? Hum. Vaccin

11. Wang Xiaofeng, Zhu Motao, Li Jingyuan*. Biomedical Effects and Nanosafety of Engineered Nanomaterials: Recent Progress. Chin

12. Yun Wang, Motao Zhu, Bing Wang, Meng Wang, Huajian Wang, Hong OuYang, Weiyue Feng. In Vitro Cytotoxicity of Transparent Yellow Iron Oxide Nanoparticles on Human Glioma Cells. J. Nanosci. Nanotechnol

13. Huajian Wang, Xianmei Du, Meng Wang, Tiancheng Wang, Hong Ouyang, Bing Wang, Motao Zhu, Yun Wang, Guang Jia, Weiyue Feng. Using ion-pair reversed-phase HPLC ICP-MS to simultaneously determine Cr(III) and Cr(VI) in urine of chromate workers

14. Bing Wang,Weiyue Feng, Motao Zhu, Yun Wang, Meng Wang, Yiqun Gu, Hong Ouyang, Huajian Wang, Ming Li, Yuliang Zhao. Neurotoxicity of low-dose repeatedly intranasal instillation of nano- and submicron-sized ferric oxide particles in mice. J. Nanopart

15. Bing Wang, Yun Wang, Weiyue Feng,Motao Zhu, Haifang Wang，Hong Ouyang, Meng Wang, Ming Li, Yuliang Zhao, Chai Zhifang. Trace Metal Disturbance in Mice Brain after Intranasal Exposure of Nano- and Submicron-Sized Fe2O3 Particles. Chem. Anal

16. Meng Wang, Weiyue Feng, Junwen Shi, Fang Zhang, Bing Wang, Motao Zhu, Bai Li, Yuliang Zhao, Zhifang Chai. Development of a Mild Mercaptoethanol Extraction Method for Determination of Mercury Species in Biological Samples by HPLCu2013ICP-MS

17. Meng Wang ,Weiyue Feng , Wenwei Lu , Bai Li , Bing Wang , Motao Zhu , Yun Wang ,Hui Yuan ,Yuliang Zhao ,and Zhifang Chai. Quantitative Analysis of Proteins via Sulfur Determination by HPLC Coupled to Isotope Dilution ICP-MS with a Hexapole Collision Cell. Anal. Chem.

1.國(guó)家自然科學(xué)基金 青年基金 膜泡系統(tǒng)介導(dǎo)的納米顆粒細(xì)胞外排和肺外信號(hào)轉(zhuǎn)導(dǎo)機(jī)制研究 項(xiàng)目負(fù)責(zé)人

2.國(guó)家重大科學(xué)研究計(jì)劃（973項(xiàng)目）基于腫瘤微環(huán)境調(diào)控的抗腫瘤納米材料設(shè)計(jì)和機(jī)制研究 項(xiàng)目骨干