欧美在线一级ⅤA免费观看,好吊妞国产欧美日韩观看,日本韩国亚洲综合日韩欧美国产,日本免费A在线

    <menu id="gdpeu"></menu>

  • 陳匡時

    陳匡時(研究員)

    陳匡時,博士、特聘研究員,生物醫(yī)學(xué)工程系特聘研究員。


    教育經(jīng)歷

    1996-2000 學(xué)士: 加州大學(xué)-圣地亞哥校區(qū) (UC San Diego) 專業(yè):生物醫(yī)學(xué)工程

    2000-2002 碩士: 加州大學(xué)-圣地亞哥校區(qū) (UC San Diego) 專業(yè):生物醫(yī)學(xué)工程

    2004-2008 博士:賓夕法尼亞大學(xué)(University of Pennsylvania) 專業(yè):生物醫(yī)學(xué)工程

    主要科研工作經(jīng)歷

    2013-至今,北京大學(xué)工學(xué)院生物醫(yī)學(xué)工程系- 特聘研究員

    2010-2013, 美國國家衛(wèi)生研究院 (NIH),Jennifer Lippincott-Schwartz 實(shí)驗室,博士后

    2010-2012,美國國家標(biāo)準(zhǔn)與技術(shù)研究院(NIST),Anne L. Plant 實(shí)驗室,博士后

    2009/2010,美國賓夕法尼亞大學(xué),Andrew Tsourkas 實(shí)驗室,博士后

    獲得榮譽(yù)

    The US. National Research Council (NRC) Research Associate Fellowship (2010-2012).

    Solomon R. Pollack Award for Excellence in Graduate Bioengineering Research (Best Ph.D. Thesis)(2009)

    主要論文

    1. Chen, A.K., Sengupta, P., Waki, K., Van Engelenburg, S., Ochiya, T., Ablan, S.D., Freed, E.O. and Lippincott-Schwartz, J. MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production. Proc. Natl. Acad. Sci. U S A., 2014: 111(26):E2676-83.

    2. Chung, K.H.,Chen, A.K., Anderton, C.R., Bhadriraju, K., Plant, A.L., Bush, B.G., Cook, R.F. and Frank F. Frictional properties of native and functionalized type I collagen thin films. Appl. Phys. Lett. 103 (14), 143703-143703-5.

    3. Chen, A.K.* Delrio, F., Peterson, A.W., Chung, K.H., Bhadriraju, K, and Plant, A.L. Cell spreading and proliferation in response to the composition and mechanics of engineered fibrillar extracellular matrices. *Corresponding Author. Biotechnol Bioeng. 2013: 110: 2731-2741.

    4. Chen, A.K.* and Tsourkas A. Developing Molecular-Beacon Constructs for Improved Live-Cell Analysis and Imaging of RNA. *Corresponding Author. Am. Biotech. Lab. 2010; 28 (7): 10-13. (Review).

    5. Chen, A.K., Davydenko, O., Behlke, M., and Tsourkas A.* Ratiometric Bi-Molecular Beacons: Ratiometric Bimolecular Beacons for the Sensitive Detection of RNA in Single Living Cells. Nucleic Acids Res. 2010; 38 (14): e148.

    6. Cheng, Z.,Chen, A.K., Lee H-Y., and Tsourkas, A.* Examination of Folate-Targeted Liposomes with Encapsulated Poly(2-Propylacrylic acid) as a pH-responsive Nanoplatform for Cytosolic Drug Delivery. Small. 2010; 6 (13): 1398-401.

    7. Chen, A.K.,Behlke, M., and Tsourkas, A.* Subcellular Trafficking and Functionality of 2’-O-methyl and 2’-O-methy-phosphorothioate Molecular Beacons. Nucleic Acids Res. 2009; 37 (22): e149.

    8. Chen, A.K.and Tsourkas, A.* Imaging RNA in Living Cells with Molecular Beacons: Current Perspectives and Challenges. J. Innov. Opt. Health Sc. 2009; 2 (4): 315-324. (Review)

    9. Chen, A.K., Cheng, Z., Behlke, M., and Tsourkas, A.* “Assessing the Sensitivity of Commercially Available Fluorophores to the Intracellular Environment”. Anal Chem. 2008; 80 (19): 7437-44.

    10. Chen, A.K., Behlke, M., and Tsourkas, A.* “Efficient Cytosolic Delivery of Molecular Beacon Conjugates and Flow Cytometric Analysis of Target RNA”. Nucleic Acids Res. 2008; 36 (12): e69.

    11. Elias, D.R., Thorek, D.L.,Chen, A.K., Czupryna, J., and Tsourkas, A.* “In vivo Imaging of Cancer Biomarkers Using Activatable Molecular Probes”. Cancer Biomarkers. 2008; 4 (6): 287-305. (Review).

    12. Chen, A.K., Behlke, M., and Tsourkas, A.* “Avoiding False-Positive Signals with Nuclease-Vulnerable Molecular Beacons in Single Living Cells”. Nucleic Acids Res. 2007; 35 (16): e105.

    13. Chen, A.K., Latz, M.I., Sobolewski, P., and Frangos, J.A.* “Evidence for the Role of G-Proteins in Flow Stimulation of Dinoflagellate Bioluminescence.” Am J Physiol Regul Integr Comp Physiol. 2007; 292(5): R2020-7.

    14. Thorek, D.L.J.,Chen, A.K., Czupryna, J., and Tsourkas, A.* “Superparamagnetic Iron Oxide Nanoparticle Probes for Molecular Imaging.” Ann Biomed Eng. 2006; Jan;34(1):23-38 (Review).

    15.Chen, A.K., Latz, M.I., and Frangos, J.A.* The Use of Dinoflagellate Bioluminescence to Characterize Cell Stimulation in Bioreactors.” Biotechnol Bioeng. 2003; 83(1): 93-103.

    出版書籍

    1. Chen, A.K.,Rhee, W.J., Bao G. and Tsourkas A.* (2011)Delivery of Molecular Beacons for Live-cell Imaging and Analysis of RNA, RNA Detection and Visualization, Jeffrey E. Gerst, Humana Press, pp 159-174.

    2.Crayton, S.H.,Chen, A.K.,Cheng, Z.,Tsourkas, A.*(2010) Molecular Imaging InComprehensive Biomaterials, edited by Ducheyne, P., Healy, K., Hutmacher, D., Kirkpatrick, J., Elsevier Inc.

    3.Thorek, D.L.J., Czupryna, J.,Chen, A.K., Tsourkas, A.* (2006) Molecular Imaging of Cancer with Superparamagnetic Iron Oxide Nanoparticles. InCancer Imaging,edited by M.A. Hayat. Elsevier Science/Academic Press.

    專利

    1.Andrew Tsourkas andAntony Chen. Quantitative Molecular Probes, 2007. US Application Number: 12/282.612; International Application Number: PCT/US07/064099.

    2.Andrew Tsourkas andAntony Chen. Novel Molecular Beacons. 2009. US Application Number: 61/244,378; International Application Number: PCT/US10/49301

    TAGS:
    名人推薦
    • 后藤田正晴(1914年8月9日 - 2005年9月19日),男,日本政治家,田中派骨干分子之一。于1982年11月開始在中曾根康弘內(nèi)閣擔(dān)任內(nèi)閣官房長官。1985年8月15日,時任日本首相..
    • 徐廷柱(生卒年不詳),字中立,南直隸蘇州府吳縣(今屬江蘇)人,徐如珂次子,明代學(xué)者。
    • 林日尊,(?-1940)漢族、馬來西亞人,空軍烈士。
    • 鄭健杰,男,安徽六安市人,出生于六安市霍山縣百合鎮(zhèn)書香世家,幼承家學(xué),酷愛書畫,既注重傳統(tǒng)的繼承,又著力于新意的創(chuàng)造,其小寫意花鳥追隨宋元,今習(xí)明清諸家,已...
    • 潘萬才(1842-1907年),安徽省潁州府阜陽縣(今安徽省阜陽市)人,清末淮軍將領(lǐng)。同治六年,任游擊。同治十一年,賜號色克巴圖魯。光緒七年,以總兵記名簡放。光緒九...
    • 蔡媽夫人本名蔡紅亨,琉球國第二尚氏王朝閩人三十六姓蔡姓后裔,生活于明朝萬歷年間。
    名人推薦