科研方向
生物化學(xué)與分子生物學(xué)
著述成果
課題研究
納米藥物對腫瘤血管的抑制作用及抑制腫瘤轉(zhuǎn)移的功能；
發(fā)表論文及專利（近3年代表作3-5篇）
?1. Qianqian Yu, Yanyu Liu, Jingnan Zhang, Fang Yang, Dongdong Sun, Du Liu, Yanhui Zhou* and Jie Liu*. ?Ruthenium(II) polypyridyl complexes as G-quadruplex inducing and stabilizing ligands in telomeric DNA. METALLOMICS?: 2013,5(3), 222-231.
2. Licong Yang, Jingnan Zhang, Chuan Wang, Xiuying Qin, Qianqian Yu, Yanhui Zhou*and Jie Liu*.Interaction between 8-hydroxyquinoline ruthenium(II) complexes and basic fibroblast growth factors (bFGF): inhibiting angiogenesis and tumor growth through ERK and AKT signaling pathways. METALLOMICS: 2014, 6, 518-531.
3. Jingnan Zhang, Qianqian Yu, Qian Li, Licong Yang, Lanmei Chen, Yanhui Zhou*, Jie Liu*. A ruthenium(II) complex capable of inducing and stabilizing bcl-2 G-quadruplex formation as a potential cancer inhibitor. Journal of Inorganic Biochemistry: 2014, 134, 1-11.
專利：
1、劉杰，周艷暉，劉亞楠，孫冬冬，張蓉。.功能化納米硒在抑制腫瘤血管生成和抗腫瘤藥物中的應(yīng)用；發(fā)明專利，已授權(quán)，專利號ZL 2012 1 0101200.7，授權(quán)公告日，2014. 10.29
2、劉杰，袁方，周艷暉，孫冬冬，劉亞楠. 一種能抑制血管形成的釕配合物及其制備方法與應(yīng)用；發(fā)明專利，已授權(quán)，專利號，ZL2011 10327452.7授權(quán)公告日，2014.07.02 。