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  • 周翊峰

    周翊峰

    周翊峰,男,畢業(yè)于中國協(xié)和醫(yī)科大學(xué)/中國醫(yī)學(xué)科學(xué)院,蘇州大學(xué)教授。


    基本信息

    姓 名:周翊峰
    技術(shù)職稱:教授
    導(dǎo)師類型:碩導(dǎo)
    所在學(xué)系:遺傳學(xué)
    學(xué)科專業(yè):遺傳學(xué)

    個人簡介

    2005年畢業(yè)于中國協(xié)和醫(yī)科大學(xué)/中國醫(yī)學(xué)科學(xué)院,獲得博士學(xué)位。2005-2008年期間在美國華盛頓大學(xué)(University of Washington)從事腫瘤免疫學(xué)方面的博士后研究。2008年9月,作為引進人才,經(jīng)招聘到蘇州大學(xué)工作,并被聘為教授。至2014年,已在國內(nèi)外專業(yè)雜志發(fā)表論文70篇,其中SCI雜志60篇?侷.F.超過300,總引用次數(shù)1600余次,其中他引1000余次(引證文獻作者不包括被引文獻的任意作者);第一和通訊作者31篇(總I.F.超過120):包括“Journal of Experimental Medicine” (I.F. 14.48) 、“Gastroenterology(I.F. 12.82)”、“Cancer Research”(3篇,I.F. 8.23)、“Carcinogenesis”(5篇,I.F. 5.70)、“International Journal of Cancer”(I.F. 5.44) 、“Breast Cancer Research and Treatment” (I.F. 4.86) 和“Cancer Science” (I.F. 3.85)等;個人H因子22(H-index)。并以第一發(fā)明人申請國家發(fā)明專利四項,授權(quán)專利三項。

    研究方向

    腫瘤遺傳學(xué)

    腫瘤病因?qū)W

    社會兼職

    1.中國抗癌協(xié)會腫瘤病因?qū)W會專業(yè)委員會委員

    周翊峰

    2.中華預(yù)防醫(yī)學(xué)雜志通訊編委

    3.Breast Cancer Research and Treatment雜志審稿人

    4.European Journal of Cancer雜志審稿人

    5.Molecular Carcinogenesis雜志審稿人

    6.DNA ad Cell Biology雜志審稿人

    7.Cancer Epidemiology雜志審稿人

    8.Tumor Biology雜志審稿人

    科研項目

    1.國家自然科學(xué)基金(No.81171895)“X染色體失活中心區(qū)域內(nèi)遺傳變異與乳腺癌發(fā)生發(fā)展關(guān)聯(lián)研究”2012.01-2015.12; 主持人

    2.國家自然科學(xué)基金(No.81001278)“11p13拷貝數(shù)多態(tài)與正常核型急性髓系白血病發(fā)生發(fā)展的關(guān)聯(lián)研究”2011.01-2013.12;主持人

    3.江蘇省自然科學(xué)基金(No. BK2011297)“Xq13染色體區(qū)域內(nèi)遺傳變異與宮頸癌發(fā)生發(fā)展的關(guān)聯(lián)研究”2011.07-2014.06;主持人

    4.江蘇省六大人才高峰(第八批);主持人

    5.教育部歸國留學(xué)人員科研啟動基金(No.20101561)“CD25基因遺傳變異與乳腺癌的相關(guān)性研究”2011.05-2012.04;主持人

    6.華南腫瘤學(xué)國家重點實驗室開放課題“CD226基因3u2019UTR區(qū)域microRNA結(jié)合位點內(nèi)遺傳多態(tài)與乳腺癌的相關(guān)性研究” 2010.05-2012.04;主持人

    7.呼吸疾病國家重點實驗室開放課題“FOXP3基因遺傳變異與女性肺腺癌發(fā)生發(fā)展的關(guān)聯(lián)研究”2012.01-2013.12;主持人

    主要論文

    (1) Li W, Zheng J, Deng J, You Y, Wu H, Li N, Lu J,Zhou Y*. Increased Levels of the Long Noncoding RNA POU3F3 Promote DNA Methylation in Esophageal Squamous Cell Carcinoma Cells.Gastroenterology.146(7):1714-1726;2014 .*通訊作者,本期封面推薦文章)

    (2) Wu H, Zheng J, Deng J, Hu M, You Y, Li N, Li W, Lu J,Zhou Y*. A genetic polymorphism in lincRNA-uc003opf.1 is associated with susceptibility to esophageal squamous cell carcinoma in Chinese populations.Carcinogenesis.34(12):2908-17; 2013.*通訊作者)

    (3) Zheng J, Deng J, Xiao M, Yang L, Zhang L, You Y, Hu M, Li N, Wu H, Li W, Lu J,Zhou Y*. A sequence polymorphism in miR-608 predicts recurrence after radiotherapy for nasopharyngeal carcinoma.Cancer Res.73(16):5151-62; 2013.*通訊作者)

    (4) Wu H, Deng J, Zheng J, You Y, Li N, Li W, Wu D,Zhou Y*. Functional polymorphisms in the CD44 gene and acute myeloid leukemia cancer risk in a Chinese population.Mol Carcinog.2013 Sep 4. [Epub ahead of print]*通訊作者)

    (5) Zheng J, Deng J, Jiang L, Yang L, You Y, Hu M, Li N, Wu H, Li W, Li H, Lu J, Zhou Y*. Heterozygous genetic variations of FOXP3 in Xp11.23 elevate breast cancer risk in Chinese population via skewed X-chromosome inactivation.Hum Mutat.34(4):619-28; 2013.(*通訊作者)

    (6) You Y, Deng J, Zheng J, Hu M, Li N, Wu H, Li W, Lu J,Zhou Y*. IL-21 gene polymorphism is associated with the prognosis of breast cancer in Chinese populations.Breast Cancer Res Treat.137(3):893-901;2013.*通訊作者)

    (7) Li N, Xu Y, Zheng J, Jiang L, You Y, Wu H, Li W, Wu D,Zhou Y*. NBS1 rs1805794G>C polymorphism is associated with decreased risk of acute myeloid leukemia in a Chinese population.Mol Biol Rep.40(5):3749-56; 2013.*通訊作者)

    (8) Zheng J, Jiang L, Zhang L, Yang L, Deng J, You Y, Li N, Wu H, Li W, Lu J,Zhou Y*. Functional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populations.Carcinogenesis.33(12):2409-16; 2012.*通訊作者)

    (9) Jiang L, Deng J, Zhu X, Zheng J, You Y, Li N, Wu H, Lu J,Zhou Y*. CD44 rs13347 C>T polymorphism predicts breast cancer risk and prognosis in Chinese populations.Breast Cancer Res.14(4):R105; 2012.*通訊作者)

    (10) Hu M, Jian L, Zhang L, Zheng J, You Y, Deng J, Li H,Zhou Y*. Functional polymorphism in the EpCAM gene is associated with occurrence and advanced disease status of cervical cancer in Chinese population.Mol Biol Rep.39(7):7303-9;2012.*通訊作者)

    (11) Hu Y, Jiang L, Zheng J, You Y,Zhou Y*, Jiao S. Association between the p73 exon 2 G4C14-to-A4T14 polymorphism and cancer risk: a meta-analysis.DNA Cell Biol.31(2):230-7; 2012.*通訊作者)

    (12) Zheng J, Chen S, Jiang L, You Y, Wu D,Zhou Y*. Functional genetic variations of cyclooxygenase-2 and susceptibility to acute myeloid leukemia in a Chinese population.Eur J Haematol.87(6):486-93; 2011.*通訊作者)

    (13) Zheng J, Liu B, Zhang L, Jiang L, Huang B, You Y, Jiang Q, Zhang S, Lu J,Zhou Y*. The protective role of polymorphism MKK4-1304 T>G in nasopharyngeal carcinoma is modulated by Epstein-Barr virus’ infection status.Int J Cancer.130(9):1981-90;2012.*通訊作者)

    (14) Zheng J, Zhang C, Jiang L, You Y, Liu Y, Lu J,Zhou Y*. Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma.Mol Carcinog.50(9):689-96; 2011.*通訊作者)

    (15) Jiang L, Zhou P, Sun A, Zheng J, Liu B, You Y, Zhang C, Wu D,Zhou Y*. Functional variant (-1304T>G) in the MKK4 promoter is associated with decreased risk of acute myeloid leukemia in a southern Chinese population.Cancer Sci.102(8):1462-8; 2011.*通訊作者)

    (16) Yu X, Zhang C, Sun A, Jiang L, Zheng J, You Y, Wu D,Zhou Y*. Genetic variations in CD14 promoter and acute lymphoblastic leukemia susceptibility in a Chinese population.DNA Cell Biol.30(10):777-82;2011.*通訊作者)

    (17) Jiang L, Liang J, Jiang M, Yu X, Zheng J, Liu H, Wu D,Zhou Y*. Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population.Eur J Haematol.86(3):199-205; 2011.*通訊作者)

    (18) Jiang L, Zhang C, Li Y, Yu X, Zheng J, Zou P, Li Y, Bin X, Lu J,Zhou Y*. A non-synonymous polymorphism Thr115Met in the EpCAM gene is associated with an increased risk of breast cancer in Chinese population.Breast Cancer Res Treat.126(2):487-95;2011.*通訊作者)

    (19) Zheng J, Zhang C, Jiang L, You Y, Liu Y, Lu J,Zhou Y*. Functional NBS1 polymorphism is associated with occurrence and advanced disease status of nasopharyngeal carcinoma.Mol Carcinog.50(9):689-96; 2011.*通訊作者)

    (20) Xu J, He X, Jin L, Jiang L,Zhou Y*, Kang Z, Peng R, Lee ST. A protein-based electrochemical method for label-free characterization of sequence-specific protein-DNA interactions.Electrochim Acta.56:5759-5765; 2011.*通訊作者)

    (21) Jiang L, Zhou P, Sun A, Zheng J, Liu B, You Y, Zhang C, Wu D,Zhou Y*. Functional variant (-1304T>G) in the MKK4 promoter is associated with decreased risk of acute myeloid leukemia in a southern Chinese population.Cancer Sci.102(8):1462-8; 2011.*通訊作者)

    (22) Yu X, Zhang C, Sun A, Jiang L, Zheng J, You Y, Wu D,Zhou Y*. Genetic variations in CD14 promoter and acute lymphoblastic leukemia susceptibility in a Chinese population.DNA Cell Biol.30(10):777-82;2011.*通訊作者)

    (23) Jiang L, Liang J, Jiang M, Yu X, Zheng J, Liu H, Wu D,Zhou Y*. Functional polymorphisms in the NBS1 gene and acute lymphoblastic leukemia susceptibility in a Chinese population.Eur J Haematol.86(3):199-205; 2011.*通訊作者)

    (24) Zheng J, Yu X, Jiang L, Xiao M, Bai B, Lu J,Zhou Y*. Association between the Cytotoxic T-lymphocyte antigen 4 +49G > A polymorphism and cancer risk: a meta-analysis.BMC Cancer.10:522; 2010.*通訊作者)

    (25) Gao Y, He Y, Ding J, Wu K, Hu B, Liu Y, Wu Y, Guo B, Shen Y, Landi D, Landi S,Zhou Y*, Liu H. An insertion/deletion polymorphism at miRNA-122-binding site in the interleukin-1alpha 3’ untranslated region confers risk for hepatocellular carcinoma.Carcinogenesis.30(12):2064-9;2009.*通訊作者)

    (26) Sun T,Zhou Y*, Yang M, Hu Z, Tan W, Han X, Shi Y, Yao J, Guo Y, Yu D, Tian T, Zhou X, Shen H, Lin D. Functional genetic variations in CTLA-4 and susceptibility to multiple types of cancer.Cancer Res.2008 68:7025-7034.*共同第一作者)

    (27) Sun T,Zhou Y*, Li H, Han X, Shi Y, Wang L, Miao X, Tan W, Zhao D, Zhang X, Guo Y, Lin D. FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer.J Exp Med.2005 202:967-974.*共同第一作者)

    (28)Zhou Y, Yu C, Miao X, Wang Y, Tan W, Sun T, Zhang X, Xiong P, Lin D. Functional haplotypes in the promoter of matrix metalloproteinase-2 and lung cancer susceptibility.Carcinogenesis.2005 26:1117-1121.

    (29) Yu C,Zhou Y*, Miao X, Xiong P, Tan W, Lin D. Functional haplotypes in the promoter of matrix metalloproteinase-2 predict risk of the occurrence and metastasis of esophageal cancer.Cancer Res.2004 64:7622-7628.*共同第一作者)

    (30)Zhou Y, Yu C, Miao X, Tan W, Liang G, Xiong P, Sun T, Lin D. Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes.Carcinogenesis.2004 25:399-404.

    (31) Yang L, Yang X, Ji W, Deng J, Qiu F, Yang R, Fang W, Zhang L, Huang D, Xie C, Zhang H, Zhong N, Ran P,Zhou Y, Lu J. Effects of a Functional Variant c.353T>C in Snai1 on Risk of Two Contextual Diseases. Chronic Obstructive Pulmonary Disease and Lung Cancer.Am J Respir Crit Care Med.189(2):139-48; 2014.

    (32) Yang L, Liu B, Qiu F, Huang B, Li Y, Huang D, Yang R, Yang X, Deng J, Jiang Q,Zhou Y,Lu J. The effect of functional MAPKAPK2 copy number variation CNV-30450 on elevating nasopharyngeal carcinoma risk is modulated by EBV infection.Carcinogenesis.35(1):46-52; 2014.

    (33) Yang R, Yang L, Qiu F, Zhang L, Wang H, Yang X, Deng J, Fang W,Zhou Y, Lu J. Functional genetic polymorphisms in PP2A subunit genes confer increased risks of lung cancer in southern and eastern Chinese.PLoS One.8(10):e77285; 2013.

    (34) Wu C, Li D, Jia W, Hu Z,Zhou Y, Yu D, Tong T, Wang M,Lin D, Qiao Y, Zhou Y, Chang J, Zhai K, Wang M, Wei L, Tan W, Shen H, Zeng Y,Lin D. Genome-wide association study identifies common variants in SLC39A6 associated with length of survival in esophageal squamous-cell carcinoma.Nat Genet.45(6):632-8; 2013.

    (35) Qiu F, Yang L, Fang W, Li Y, Yang R, Yang X, Deng J, Huang B, Xie C,Zhou Y,Lu J. A functional polymorphism in the promoter of ERK5 gene interacts with tobacco smoking to increase the risk of lung cancer in Chinese populations.Mutagenesis.28(5):561-7; 2013.

    (36) Cheng M, Yang L, Yang R, Yang X, Deng J, Yu B, Huang D, Zhang S, Wang H, Qiu F,Zhou Y,Lu J. A microRNA-135a/b binding polymorphism in CD133 confers decreased risk and favorable prognosis of lung cancer in Chinese by reducing CD133 expression.Carcinogenesis.34(10):2292-9; 2013.

    (37) Wu C, Chang J, Ma B, Miao X,Zhou Y, Liu Y, Li Y, Wu T, Hu Z, Shen H, Jia W, Zeng Y,Lin D, Kraft P. The case-only test for gene-environment interaction is not uniformly powerful: an empirical example.Genet Epidemiol.37(4):402-7; 2013.

    (38) Xie C, Yang L, Yang X, Yang R, Li Y, Qiu F, Chen M, Fang W, Bin X, Deng J, Huang D, Liu B,Zhou Y, Lu J. Sipa1 promoter polymorphism predicts risk and metastasis of lung cancer in Chinese.Mol Carcinog.2013 Nov; [Epub ahead of print]

    (39) Yang L, Liu B, Huang B, Deng J, Li H, Yu B, Qiu F, Cheng M, Wang H, Yang R, Yang X,Zhou Y, Lu J. A functional copy number variation in WWOX gene is associated with lung cancer risk in Chinese.Hum Mol Genet. 22(9):1886-94; 2013.

    (40) Huang D, Yang L, Liu Y, Zhou Y, Guo Y, Pan M, Wang Y, Tan Y, Zhong H, Hu M, Lu W, Ji W, Wang J, Ran P, Zhong N,Zhou Y, Lu J. Functional polymorphisms in NFκB1/IκBα predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.Hum Genet.2013 Jan 16. [Epub ahead of print]

    (41) Huang L, Wu C, Yu D, Wang C, Che X, Miao X, Zhai K, Chang J, Jiang G, Yang X, Cao G, Hu Z, Zhou Y, Zuo C, Wang C, Zhang X,Zhou Y, Yu X, Dai W, Li Z, Shen H, Liu L, Chen Y, Zhang S, Wang X, Liu Y, Sun M, Cao W, Gao J, Ma Y, Zheng X, Cheung ST, Jia Y, Tan W, Wu T, Lin D. Identification of common variants in BRCA2 and MAP2K4 for susceptibility to sporadic pancreatic cancer.Carcinogenesis. 34(5):1001-5; 2013.

    (42) Jin G, Ma H, Wu C, Dai J, Zhang R, Shi Y, Lu J, Miao X, Wang M,Zhou Y, Chen J, Li H, Pan S, Chu M, Lu F, Yu D, Jiang Y, Dong J, Hu L, Chen Y, Xu L, Shu Y, Pan S, Tan W, Zhou B, Lu D, Wu T, Zhang Z, Chen F, Wang X, Hu Z, Lin D, Shen H. Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.Am J Hum Genet.91(5):928-34; 2012.

    (43) Yang L, Qiu F, Lu X, Huang D, Ma G, Guo Y, Hu M, Zhou Y, Pan M, Tan Y, Zhong H, Ji W, Wei Q, Ran P, Zhong N,Zhou Y, Lu J. Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.PLoS One.7(10):e46071;2012.

    (44) You Y, Deng J, Zheng J, Jiang L, Li N, Wu H, Li W, Lu J,Zhou Y, Ni B. Functional polymorphisms in PIN1 promoter and esophageal carcinoma susceptibility in Chinese population.Mol Biol Rep.40(2):829-38;2013.

    (45) Wu C, Kraft P, Zhai K, Chang J, Wang Z, Li Y, Hu Z, He Z, Jia W, Abnet CC, Liang L, Hu N, Miao X,Zhou Y, Liu Z, Zhan Q, Liu Y, Qiao Y, Zhou Y, Jin G, Guo C, Lu C, Yang H, Fu J, Yu D, Freedman ND, Ding T, Tan W, Goldstein AM, Wu T, Shen H, Ke Y, Zeng Y, Chanock SJ, Taylor PR, Lin D. Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.Nat Genet.44(10):1090-7;2012.

    (46) Liu B, Yang L, Huang B, Cheng M, Wang H, Li Y, Huang D, Zheng J, Li Q, Zhang X, Ji W,Zhou Y, Lu J. A functional copy-number variation in MAPKAPK2 predicts risk and prognosis of lung cancer.Am J Hum Genet.91(2):384-90; 2012.

    (47) Huang D, Qiu F, Yang L, Li Y, Cheng M, Wang H, Ma G, Wang Y, Hu M, Ji W,Zhou Y, Lu J. The polymorphisms and haplotypes of WWOX gene are associated with the risk of lung cancer in southern and eastern Chinese populations.Mol Carcinog.2012 Jun 12. [Epub ahead of print]

    (48) Yang M, Sun T,Zhou Y, Wang L, Liu L, Zhang X, Tang X, Zhou M, Kuang P, Tan W, Li H, Yuan Q, Yu D. The functional cytotoxic T lymphocyte-associated Protein 4 49G-to-A genetic variant and risk of pancreatic cancer.Cancer.118(19):4681-6; 2012.

    (49) Huang B, Liu B, Yang L, Li Y, Cheng M, Huang D, Wang H, Zhang X, Zheng J, Li Q, Ji W,Zhou Y, Lu J. Functional genetic variants of c-Jun and their interaction with smoking and drinking increase the susceptibility to lung cancer in southern and eastern Chinese.Int J Cancer.131(5):E744-58; 2012.

    (50) Yang L, Li Y, Cheng M, Huang D, Zheng J, Liu B, Ling X, Li Q, Zhang X, Ji W,Zhou Y, Lu J. A functional polymorphism at microRNA-629-binding site in the 3’-untranslated region of NBS1 gene confers an increased risk of lung cancer in Southern and Eastern Chinese population.Carcinogenesis.33(2):338-47;2012.

    (51) Wu C, Miao X, Huang L, Che X, Jiang G, Yu D, Yang X, Cao G, Hu Z, Zhou Y, Zuo C, Wang C, Zhang X,Zhou Y, Yu X, Dai W, Li Z, Shen H, Liu L, Chen Y, Zhang S, Wang X, Zhai K, Chang J, Liu Y, Sun M, Cao W, Gao J, Ma Y, Zheng X, Cheung ST, Jia Y, Xu J, Tan W, Zhao P, Wu T, Wang C, Lin D. Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations.Nat Genet.44(1):62-6; 2011.

    (52) Shi Y, Hu Z, Wu C, Dai J, Li H, Dong J, Wang M, Miao X,Zhou Y, Lu F, Zhang H, Hu L, Jiang Y, Li Z, Chu M, Ma H, Chen J, Jin G, Tan W, Wu T, Zhang Z, Lin D, Shen H. A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.Nat Genet.43(12):1215-8;2011.

    (53) Lu J, Yang L, Zhao H, Liu B, Li Y, Wu H, Li Q, Zeng B, Wang Y, Ji W,Zhou Y. The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in Southern and Eastern Chinese populations.Hum Mutat.32(11):1299-308; 2011.

    (54) Wu C, Hu Z, He Z, Jia W, Wang F,Zhou Y, Liu Z, Zhan Q, Liu Y, Yu D, Zhai K, Chang J, Qiao Y, Jin G, Liu Z, Shen Y, Guo C, Fu J, Miao X, Tan W, Shen H, Ke Y, Zeng Y, Wu T, Lin D. Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.Nat Genet.43(7):679-84; 2011.

    (55) Ding J, Gao Y, He Y,Zhou Y, Huang M, Liu H. Screening SNPs residing in the microRNA-binding sites of hepatocellular carcinoma related genes.Int J Data Min Bioinform.5(1):1-21; 2011.

    (56) Lin D, Liu C, Xue M, Liu R, Jiang L, Yu X, Bao G, Deng F, Yu M, Ao J,Zhou Y, Wu D, Liu H. The role of interleukin-15 polymorphisms in adult acute lymphoblastic leukemia.PLoS One.5(10):e13626; 2010.

    (57) Liu P, Jaffar J,Zhou Y, Yang Y, Hellstr?m I, Hellstr?m KE. Inhibition of TGFbeta1 makes nonimmunogenic tumor cells effective for therapeutic vaccination.J Immunother.32(3):232-9; 2009.

    (58) Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, Shi Y, Tan W,Zhou Y, Zhao D, Zhang X, Guo Y, Lin D. Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer.Carcinogenesis.2007 28:1067-1073.

    (59) Yang Y, Yang S, Ye Z, Jaffar J,Zhou Y, Cutter E, Lieber A, Hellstr?m I, Hellstr?m KE. Tumor cells expressing anti-CD137 scFv induce a tumor-destructive environment.Cancer Res.2007 67:2339-2344.

    (60) Hao B, Miao X, Li Y, Zhang X, Sun T, Liang G, Zhao Y,Zhou Y, Wang H, Chen X, Zhang L, Tan W, Wei Q, Lin D, He F. A novel T-77C polymorphism in DNA repair gene XRCC1 contributes to diminished promoter activity and increased risk of non-small cell lung cancer.Oncogene.2006 25:3613-3620.

    (61) Zhang X, Miao X, Guo Y, Tan W,Zhou Y, Sun T, Wang Y, Lin D. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer.Hum Mutat.2006 27:110-117.

    (62) Zhang X, Miao X, Sun T, Tan W, Qu S, Xiong P,Zhou Y, Lin D. Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer.J Med Genet.2005 42:479-484.

    (63) Tan W, Miao X, Wang L, Yu C, Xiong P, Liang G, Sun T,Zhou Y, Zhang X, Li H, Lin D. Significant increase in risk of gastroesophageal cancer is associated with interaction between promoter polymorphisms in thymidylate synthase and serum folate status.Carcinogenesis.2005 26:1430-1435.

    (64) Sun T, Miao X, Wang J, Tan W,Zhou Y, Yu C, Lin D. Functional Phe31Ile polymorphism in Aurora A and risk of breast carcinoma.Carcinogenesis.2004 25:2225-2230.

    (65) Liang G, Miao X,Zhou Y, Tan W, Lin D. A functional polymorphism in the SULT1A1 gene (G638A) is associated with risk of lung cancer in relation to tobacco smoking.Carcinogenesis.2004 25:773-778.

    (66) 李華,郭紅燕,孫瞳,周翊峰,林東昕,章文華,喬杰。Fas和Fas配體基因啟動子單核苷酸多態(tài)性與子宮頸癌的發(fā)病風(fēng)險。《中華腫瘤雜志》2009 31: 38-41.

    (67) 張雪梅,繆小平,譚文,曲世寧,孫瞳,周翊峰,林東昕。亞甲基四氫葉酸還原酶基因遺傳變異與肺癌。《中國醫(yī)學(xué)科學(xué)院學(xué)報》2005 27:700-703.

    (68) 馮飛躍,梁剛,呂文富,繆小平,于春媛,譚文,周翊峰,孫瞳,康濱,周彤,潘凱楓,張聯(lián),林東昕。尿苷二磷酸葡糖醛酸轉(zhuǎn)移酶1A7基因多態(tài)基礎(chǔ)研究。《癌癥》2005 24:1085-1090.

    (69) 張雪梅,繆小平,熊萍,于春媛,譚文,曲世寧,孫瞳,周翊峰,林東昕;|(zhì)金屬蛋白酶2和9功能性單核苷酸多態(tài)與胃癌。《癌癥》2004 23:1233-1237

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