人物簡(jiǎn)介
張友玉，博士，二級(jí)教授，博士生導(dǎo)師。主持國(guó)家自然科學(xué)基金面上項(xiàng)目5項(xiàng)，國(guó)家基金重點(diǎn)項(xiàng)目協(xié)作項(xiàng)目1項(xiàng)，省部級(jí)重點(diǎn)及一般項(xiàng)目10余項(xiàng)。以第一作者和通訊作者在Angew. Chem. Int. Ed., Anal. Chem., Chem. Commun.等國(guó)際著名刊物上發(fā)表高水平研究論文200余篇，獲國(guó)家授權(quán)發(fā)明專(zhuān)利7項(xiàng)。獲湖南省自然科學(xué)獎(jiǎng)二等獎(jiǎng)1項(xiàng)，湖南省科學(xué)技術(shù)進(jìn)步獎(jiǎng)二等獎(jiǎng)1項(xiàng)，中國(guó)分析測(cè)試學(xué)會(huì)科學(xué)技術(shù)獎(jiǎng)（CAIA獎(jiǎng)）二等獎(jiǎng)1項(xiàng)。獲2018年湖南師范大學(xué)芙蓉百崗明星稱(chēng)號(hào)。
研究方向
化學(xué)生物學(xué)及納米分析化學(xué)等領(lǐng)域
主持的課題部分
1. 國(guó)家自然科學(xué)基金（21874042）, 癌細(xì)胞外泌體的生物分析新方法與臨床樣品檢測(cè)研究。在研。
2. 國(guó)家自然科學(xué)基金（21475043）, Ⅳ族元素量子點(diǎn)的電化學(xué)制備及其在生物分析中的應(yīng)用。
3. 國(guó)家自然科學(xué)基金（21275051）, 基于上轉(zhuǎn)換納米編碼探針的多種腫瘤標(biāo)志物同時(shí)檢測(cè)技術(shù)。
4. 國(guó)家自然科學(xué)基金（20975037）, 基于功能化蛋白核殼納米編碼信標(biāo)的核酸適體陣列傳感技術(shù)研究。
5. 國(guó)家自然科學(xué)基金（20675030）, 基于納米顆粒編碼的DNA單堿基突變檢測(cè)技術(shù)研究。
6. 國(guó)家自然科學(xué)基金協(xié)作項(xiàng)目，生物熒光探針的合成與表征。
代表性論文部分
1. Feng Chen，Qiujun Lu，Linna Huang，Biwu Liu，Meiling Liu，Youyu Zhang*，Juewen Liu*, DNA Triplex and Quadruplex Assembled Nanosensors for Correlating Kand pH in Lysosomes.Angewandte Chemie International Edition,2020.(DOI:10.1002/anie.202013302)
2. Jianhui Deng，Qiujun Lu，Yuxin Hou，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Nanosensor Composed of Nitrogen-Doped Carbon Dots and Gold Nanoparticles for Highly Selective Detection of Cysteine with Multiple Signals.Analytical Chemistry,2015 87,(4),2195-2203.
3. Xiaojiao Chen，Yangzhong Wang，Youyu Zhang*，Zhuhai Chen，Yang Liu*，Zhaolong Li，Jinghong Li, Sensitive Electrochemical Aptamer Biosensor for Dynamic Cell Surface N-Glycan Evaluation Featuring Multivalent Recognition and Signal Amplification on a Dendrimer-Graphene Electrode Interface.Analytical Chemistry,2014 86,(9),4278-4286.
4. Yinhui Yi，Gangbing Zhu，Chang Liu，Yan Huang，Youyu Zhang*，Haitao Li，Jiangna Zhao，Shouzhuo Yao, A Label-Free Silicon Quantum Dots-Based Photoluminescence Sensor for Ultrasensitive Detection of Pesticides.Analytical Chemistry,2013 85,(23),11464-11470.
5. Youyu Zhang，Zhiwen Tang，Jun Wang，Hong Wu，Aihui Maham，Yuehe Lin*, Hairpin DNA Switch for Ultrasensitive Spectrophotometric Detection of DNA Hybridization Based on Gold Nanoparticles and Enzyme Signal Amplification.Analytical Chemistry,2010 82,(15),6440-6446.
6. Qiujun Lu，Jianhui Deng，Yuxin Hou，Haiyan Wang，Haitao Li，Youyu Zhang*, One-step electrochemical synthesis of ultrathin graphitic carbon nitride nanosheets and their application to the detection of uric acid.Chemical Communications,2015 51,(61),12251-12253.
7. Qiujun Lu，Jianhui Deng，Yuxin Hou，Haiyan Wang，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Hydroxyl-rich C-dots synthesized by a one-pot method and their application in the preparation of noble metal nanoparticles.Chemical Communications,2015 51,(33),7164-7167.
8. Qiong Chen，Meiling Liu，Jiangna Zhao，Xue Peng，Xiaojiao Chen，Naxiu Mi，Bangda Yin，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Water-dispersible silicon dots as a peroxidase mimetic for the highly-sensitive colorimetric detection of glucose.Chemical Communications,2014 50,(51),6771-6774.
9. Mingjie Wei，Peng Yin，Youming Shen，Lingli Zhang，Jianhui Deng，Shanyan Xue，Haitao Li，Bin Guo，Youyu Zhang*，Shouzhuo Yao, A new turn-on fluorescent probe for selective detection of glutathione and cysteine in living cells.Chemical Communications,2013 49,(41),4640-4642.
10. Yinhui Yi，Jianhui Deng，Youyu Zhang*，Haitao Li，Shouzhuo Yao, Label-free Si quantum dots as photoluminescence probes for glucose detection.Chemical Communications,2013 49,(6),612-614.
11. Jianhui Deng，Qiujun Lu，Naxiu Mi，Haitao Li，Meiling Liu，Mancai Xu，Liang Tan，Qingji Xie，Youyu Zhang*，Shouzhuo Yao, Electrochemical Synthesis of Carbon Nanodots Directly from Alcohols.Chemistry-a European Journal,2014 20,(17),4993-4999.
12. Youyu Zhang，Zhiwen Tang，Jun Wang，Hong Wu，Chiann-Tso Lin，Yuehe Lin*, Apoferritin nanoparticle: a novel and biocompatible carrier for enzyme immobilization with enhanced activity and stability.Journal Of Materials Chemistry,2011 21,(43),17468-17475.
13. Mingxia Li，Haiyan Wang，Xiaoxia Wang，Qiujun Lu，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Ti3C2/Cu2O heterostructure based signal-off photoelectrochemical sensor for high sensitivity detection of glucose.Biosensors & Bioelectronics,2019 142.
14. Qiujun Lu，Haiyan Wang，Yalan Liu，Yuxin Hou，Haitao Li，Youyu Zhang*, Graphitic carbon nitride nanodots: As reductant for the synthesis of silver nanoparticles and its biothiols biosensing application.Biosensors & Bioelectronics,2017 89411-416.
15. Aijin Fang，Hongyu Chen，Haitao Li，Meiling Liu*，Youyu Zhang*，Shouzhuo Yao, Glutathione regulation-based dual-functional upconversion sensing-platform for acetylcholinesterase activity and cadmium ions.Biosensors & Bioelectronics,2017 87545-551.
16. Aijin Fang，Qiongqiong Wu，Qiujun Lu，Hongyu Chen，Haitao Li，Meiling Liu*，Youyu Zhang*，Shouzhuo Yao, Upconversion ratiometric fluorescence and colorimetric dual-readout assay for uric acid.Biosensors & Bioelectronics,2016 86664-670.
17. Qian Long，Aijin Fang，Yanqing Wen，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Rapid and highly-sensitive uric acid sensing based on enzymatic catalysis-induced upconversion inner filter effect.Biosensors & Bioelectronics,2016 86109-114.
18. Qiongqiong Wu，Aijin Fang，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Enzymatic-induced upconversion photoinduced electron transfer for sensing tyrosine in human serum.Biosensors & Bioelectronics,2016 77957-962.
19. Qian Long，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Upconversion nanoparticle-based fluorescence resonance energy transfer assay for organophosphorus pesticides.Biosensors & Bioelectronics,2015 68168-174.
20. Meiling Liu，Jianhui Deng，Qiong Chen，Yan Huang，Linping Wang，Yan Zhao，Youyu Zhang*，Haitao Li，Shouzhuo Yao*, Sensitive detection of rutin with novel ferrocene benzyne derivative modified electrodes.Biosensors & Bioelectronics,2013 41275-281.
21. Jie Zhao，Youyu Zhang*，Haitao Li，Yanqing Wen，Xiaoyu Fan，F(xiàn)anbo Lin，Liang Tan，Shouzhuo Yao, Ultrasensitive electrochemical aptasensor for thrombin based on the amplification of aptamer-AuNPs-HRP conjugates.Biosensors & Bioelectronics,2011 26,(5),2297-2303.
22. Min Ye，Youyu Zhang*，Haitao Li，Yuqin Zhang，Ping Tan，Hao Tang，Shouzhuo Yao, A novel method for the detection of point mutation in DNA using single-base-coded CdS nanoprobes.Biosensors & Bioelectronics,2009 24,(8),2339-2345.
23. Mingxia Li，Qiujun Lu，Meiling Liu，Peng Yin，Cuiyan Wu，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Photoinduced Charge Separation via the Double-Electron Transfer Mechanism in Nitrogen Vacancies g-C3N5/BiOBr for the Photoelectrochemical Nitrogen Reduction.Acs Applied Materials & Interfaces,2020 12,(34),38266-38274.
24. Dan Liu，Gong Zhang，Qinghua Ji，Youyu Zhang*，Jinghong Li*, Synergistic Electrocatalytic Nitrogen Reduction Enabled by Confinement of Nanosized Au Particles onto a Two-Dimensional Ti3C2Substrate.Acs Applied Materials & Interfaces,2019 11,(29),25758-25765.
25. Na Huang，Si Zhang，Liuqing Yang，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Multifunctional Electrochemical Platforms Based on the Michael Addition/Schiff Base Reaction of Polydopamine Modified Reduced Graphene Oxide: Construction and Application.Acs Applied Materials & Interfaces,2015 7,(32),17935-17946.
26. Qiongqiong Wu，Hongyu Chen，Aijin Fang，Xinyang Wu，Meiling Liu*，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Universal Multifunctional Nanoplatform Based on Target-Induced in Situ Promoting Au Seeds Growth to Quench Fluorescence of Upconversion Nanoparticles.Acs Sensors,2017 2,(12),1805-1813.
27. Qujun Lu，Hu Dong，Jiali Hu，Linna Huang，Youyu Zhang*，Mingxia Li，Meiling Liu，Yaqian Li，Cuiyan Wu*，Haitao Li, Insight into the Effect of Ligands on the Optical Properties of Germanium Quantum Dots and Their Applications in Persistent Cell Imaging.Langmuir,2020 36,(41),12375-12382.
28. Jiali Hu，Qiujun Lu，Cuiyan Wu，Meiling Liu，Haitao Li，Youyu Zhang*，Shouzhuo Yao, Synthesis of Fluorescent and Water-Dispersed Germanium Nanoparticles and Their Cellular Imaging Applications.Langmuir,2018 34,(30),8932-8938.
29. Haiyan Wang，Mingxia Li，Qiujun Lu，Yuemei Cen，Youyu Zhang*，Shouzhuo Yao*, A Mesoporous Rod-like g-C3N5Synthesized by Salt-Guided Strategy: As a Superior Photocatalyst for Degradation of Organic Pollutant.Acs Sustainable Chemistry & Engineering,2019 7,(1),625-631.
30. Haiyan Wang，Mingxia Li，Huan Li，Qiujun Lu，Youyu Zhang*，Shouzhuo Yao, Porous graphitic carbon nitride with controllable nitrogen vacancies: As promising catalyst for enhanced degradation of pollutant under visible light.Materials & Design,2019 162210-218.
