基本內(nèi)容
陳小川，生于1984年，博士，副教授，研究生導(dǎo)師。
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1. 受教育經(jīng)歷
2009/06u20132012/05， 美國(guó)亞利桑那大學(xué)，博士
2007/08u20132009/05， 美國(guó)亞利桑那大學(xué)，碩士
2003/09u2013 2007/06，中國(guó)西南大學(xué)，學(xué)士
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2. 研究工作經(jīng)歷
2013/01u2013至今，西南大學(xué)，動(dòng)物科技學(xué)院，副教授，研究生導(dǎo)師
2012/10u20132012/12，西南大學(xué)，動(dòng)物科技學(xué)院，講師
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3. 研究興趣與方向
主要采用動(dòng)物胎兒模型，致力于子宮內(nèi)環(huán)境對(duì)胎兒后期發(fā)育及后天生長(zhǎng)過(guò)程中的內(nèi)分泌和代謝調(diào)控研究。
1) 母體低營(yíng)養(yǎng)對(duì)胎兒在子宮內(nèi)發(fā)育及其后天生長(zhǎng)的影響。
2) 環(huán)境熱應(yīng)激對(duì)胎兒和新生兒胰腺內(nèi)分泌的調(diào)控研究。
先后主持了西南大學(xué)博士基金和中央高�；究蒲袠I(yè)務(wù)費(fèi)各1項(xiàng)；曾主要參與了美國(guó)NIH R01-DK-084842，NIH T32-HL-7249，NIH F32-DK-088514和USDA 2012-67012-19855等項(xiàng)目；并與美國(guó)亞利桑那大學(xué)（The University of Arizona）擁有非常深層次的交流與合作擔(dān)任動(dòng)物科技學(xué)院《生物化學(xué)》和《分子生物學(xué)》本科教學(xué)。。
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4. 期刊論文
（通訊作者以“*”標(biāo)出）
曾在《American Journal of Physiology Endocrinology and Metabolism》（2013年生理學(xué)類Top 7），《Journal of Physiology》（2013年生理學(xué)類Top 8）等國(guó)際一流生理學(xué)期刊和國(guó)際會(huì)議上發(fā)表論文10余篇，第一作者3篇，并編寫英文教材1部。
1) Chen X (陳小川), Green AS, Macko AR, Yates DT, Kelly AC, Limesand SW*. Enhanced insulin secretion responsiveness and islet adrenergic desensitization after chronic norepinephrine suppression is discontinued in fetal sheep. Am J Physiol Endocrinol Metab. 2014 Jan 1;306(1):E58-64. doi: 10.1152/ajpendo.00517. (2014, IF = 4.514).?
2) Macko AR, Yates DT, Chen X, Green AS, Kelly AC, Brown LD, Limesand SW*. Elevated plasma norepinephrine inhibits insulin secretion, but adrenergic blockade reveals enhanced β-cell responsiveness in an ovine model of placental insufficiency at 0.7 of gestation. J Dev Orig Health Dis. 2013 Oct 1;4(5). (2013, IF = 1.207).?
3) Yates DT, Macko AR, Chen X, Green AS, Kelly AC, Anderson MJ, Fowden AL, Limesand SW*. Hypoxaemia-induced catecholamine secretion from adrenal chromaffin cells inhibits glucose-stimulated hyperinsulinaemia in fetal sheep. The Journal of Physiology. 590(Pt 21):5439-47. (2012, IF = 4.38).?
4) Yates DT, Macko AR, Nearing M, Chen X, Rhoads RP, Limesand SW*. Developmental programming in response to intrauterine growth restriction impairs myoblast function and skeletal muscle metabolism. Journal of Pregnancy. 2012:631038. (2012).?
5) Chen X, Rozance PJ, Hay WW Jr, Limesand SW*. Insulin-like Growth Factor and Fibroblast Growth Factor Expression Profiles in Growth Restricted Fetal Sheep Pancreas. Experimental Biology and Medicine (Maywood). 237(5):524-9. (2012, IF = 2.803).?
6) Green AS, Chen X, Macko AR, Anderson MJ, Kelly AC, Hart NJ, Lynch RM, Limesand SW*. Chronic Pulsatile Hyperglycemia Reduces Insulin Secretion and Increases Accumulation of Reactive Oxygen Species in Fetal Sheep Islets. The Journal of Endocrinology. 212(3):327-42. (2011, IF = 4.746).?
7) Green AS, Macko AR, Rozance PJ, Yates DT, Chen X (陳小川), Hay WW Jr, Limesand SW*. Characterization of glucose-insulin responsiveness and impact of fetal number and gender on insulin response in the sheep fetus. American Journal of Physiology Endocrinology and Metabolism. 300(5), E817-823. (2011, IF = 4.746).?
8) Chen X, Fahy AL, Green AS, Anderson MJ, Rhoads Jr RP, Limesand SW*. β2-Adrenergic Receptor Desensitization in Perirenal Adipose Tissue in Fetuses and Lambs with Placental Insufficiency-induced Intrauterine Growth Restriction. The Journal of Physiology. 588(Pt 18):3539-49. (2010, IF = 5.139).?
9) Leos RA, Anderson MJ, Chen X, Pugmire J, Anderson KA, Limesand SW*. Chronic exposure to elevated norepinephrine suppresses insulin secretion in fetal sheep with placental insufficiency and intrauterine growth restriction. American Journal of Physiology Endocrinology and Metabolism. 298, E770-778. (2010, IF = 4.686).?
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5. 會(huì)議論文
（通訊作者以“*”標(biāo)出）
1) Chen X, Green AS, Macko AR, Anderson MJ, Zehri A, and Limesand SW*. Chronic norepinephrine infusion suppresses insulin secretion but once removed, leads to enhanced insulin secretion in the fetal sheep. Diabetes 70th Scientific Session. Abstract 2496-PO. Orlando, Florida, USA. (2010).
2) Chen X, Macko AR., Green AS, Yates DT, Anderson MJ, Kelly AC, Zehri A, and Limesand SW*. Enhanced Insulin Secretion in the Fetal Sheep after Chronic Norepinephrine Infusion Suppression. Society for Gynecologic Investigation 2011 Annual Meeting. 18(4):F-116. Miami, Florida, USA. (2011).
3) Chen X, Yates DT, Macko AR, Kelly AC, and Limesand SW*. Chronic Norepinephrine Exposure Desensitizes Fetal Sheep Islets and Enhances Insulin Secretion. Society for Gynecologic Investigation 2012 Annual Meeting. 19(3):T-088. San Diego, California, USA. (2012).
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6. 專著
1) Yates DT, Chen X, Limesand SW. Environmental Physiology of Livestock. (Environmental Heat Stress Impairs Placental Function, Fetal Growth and Development, and Postnatal Performance in Livestock). Wiley-Blackwell by John Wiley &. Sons, Inc. ISBN-13: 978-0-8138-1176-5. 368 pages. (2012).
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7. 獲獎(jiǎng)情況
陳小川，重慶市引進(jìn)高層次人才（第四類），2013
陳小川，美國(guó)亞利桑那大學(xué)E. Ray Cowden 獎(jiǎng)學(xué)金，2007-2012
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8. 研究生招生
[1] 基礎(chǔ)獸醫(yī)學(xué)（專業(yè)代碼：090601）；研究方向：動(dòng)物生理學(xué)（代碼：02）
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9. 實(shí)驗(yàn)室組員
（2013 u2013 至今）
李妍鎣，2012級(jí)動(dòng)物科學(xué)本科在讀，主要實(shí)驗(yàn)方向：RT-PCR & Real-time PCR
牟燁，2012級(jí)動(dòng)物科學(xué)本科在讀，主要實(shí)驗(yàn)方向：組織切片及免疫熒光染色
湯琦，2012級(jí)動(dòng)物科學(xué)本科在讀，主要實(shí)驗(yàn)方向：Total RNA的提取和實(shí)驗(yàn)室管理
王小巧，2012級(jí)動(dòng)物科學(xué)本科在讀，主要實(shí)驗(yàn)方向：大鼠胰島細(xì)胞提取和細(xì)胞培養(yǎng)
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聯(lián)系地址：重慶市北碚區(qū)西南大學(xué)動(dòng)物科技學(xué)院30教學(xué)樓207室
