人物經(jīng)歷
教育經(jīng)歷
1983-1991 清華大學(xué) 分析化學(xué)和物理化學(xué)學(xué)士,有機化學(xué)碩士。
1992-1997美國華盛頓州立大學(xué),生物化學(xué)博士。
工作經(jīng)歷
1991 -1992,清華大學(xué)分析化學(xué)中心,助理研究員。
1998 - 2001,美國 Molecular Structure 公司研究員,休斯敦,德克薩斯州。
2002 - 2005, Rigaku/MSC(美國) 公司高級研究員,休斯頓, 德克薩斯州。
2005 - 2007,Rigaku(美國)公司學(xué)術(shù)總監(jiān)和政府市場總監(jiān),休斯頓,德克薩斯州。
2007 - 2009,Rigaku(美國)公司,亞洲商業(yè)拓展部總監(jiān),休斯頓,德克薩斯州。
2009 -南開大學(xué)藥學(xué)院,教授。
研究方向
生物化學(xué)方向。
主要貢獻
(1). The crystal structure of cytochrome P460 from Nitrosomonas europaea reveals a novel cytochrome fold and cross-linked heme. Pearson, A. R., Elmore, B. O., Yang, C., Ferrara, J. D., Hooper, A. D. & Wilmot, C. M. Biochemistry ( 2007) 46, 8340 -8349.
(2). Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target. Laponogov1, I., Veselkov. D. A., Sohi, M. K., Pan, X.-S., Achari, A., Cheng, Y., Ferrara, J. D., Fisher, L. M., Sanderson, M. R. PLoS ONE (2007) 3, 1-9.
(3). Away from the edge II: in-house Se-SAS phasing with chromium radiation H. Xu*, C. Yang*, L. Chen, I. A. Kataeva, W. Tempel, D. Lee, J. E. Habel, D. Nguyen, J. W. Pflugrath, J. D. Ferrara, W. B. Arendall III, J. S. Richardson, D. C. Richardson, Z.-J. Liu, M. G. Newton, J. P. Rose and B.-C. Wang. Acta Cryst. (2005) D61, 960-966
(4). Structural and Biochemical Characterization of CIB1 Delineates a new Family of EF-hand containing PRO proteins. H. R. Gentry, A. U. Singer, L. Betts, C. Yang, J. D. Ferrara, J. Sondek and L. V. Parise J. Biol. Chem., (2005). 280, 8407 - 8415
(5).Structural Basis for Herbicida inhibitor selectivity revealed by comparison of crystal structures of Plant and Mammalian 4-Hydroxyphenylpyruvate dioxygenases. C. Yang, J. W. Pflugrath, D. L. Camper, M. L. foster, D. J. Pernich and T. A. Walsh. Biochemistry (2004). 43(32), 10414-10423
(6). Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae. J. D. Phillips, F. G. Whitby, C. A. Warby, P. Labbe, C. Yang, J. W. Pflugrath, J. D. Ferrara, H. Robinson, J. P. Kushner, and C. P. Hill. J. Biol. Chem., (2004). 279, 38960 u2013 38968
(7). Away from the edge: SAD phasing from the sulfur anomalous signal measured in-house with chromium radiation. C. Yang, J. W. Pflugrath, C. N. Stence, A. Courville and J. D. Ferrara. Acta cryst. (2003). D59, 1943-1957
(8). Crystal Structures of Unligated and CN-Ligated Glycera dibranchiata Monomer Ferric Hemoglobin Components III and IV. H. J. Park*, C. Yang*, N. Treff, J. D. Satterlee and C. H. Kang. Proteins: struct., funct., (2002). 49, 49-54
(9).The application of anomalous signal of sulfur from single wavelength(CuK) for routinely phasing protein diffraction data. C. Yang and J. Pflugrath. Acta Cryst. (2001). D57 1480-1490
(10). Optics systems for the home laboratory: caveat emptor. C. Yang, A. Courville and J. D. Ferrara. Acta Cryst., (1999) D55 1681-1689
(11). Stabilization of the i-motif by intramolecular adenine-adenine-thymine base triple in the crystal structure of d(ACCCT). J. K. Weil, T. Min, C. Yang, C. Sutherland, N. Sinda and C. H. Kang. Acta Cryst., (1999). D55, 422-429
(12). Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4Å resolution. C. Yang, U. Curth, C. Urbanke and C. H. Kang. Nature structure biology, (1997). 4(2) 153-157
(13). Studies on liquid Crystal/Polymer Enriching Oxygen Composite Membranes C. Yang, L. Y. Wang and Y. F. Yan. Membrane science and technology (1994). 14(1)
所獲榮譽
2020年11月,獲得第八屆中國僑界貢獻獎二等獎。