社會兼職主要有
教育部科技委化學(xué)化工學(xué)部委員
中國化學(xué)會理事、湖北省化學(xué)化工學(xué)會副理事長
湖北省硒資源開發(fā)與利用促進(jìn)會理事長
本科教學(xué)與研究生教育
本科生教學(xué):
《基礎(chǔ)化學(xué)》、《藥物化學(xué)導(dǎo)論》、《化學(xué)文獻(xiàn)》
研究生教學(xué):
《蛋白質(zhì)與核酸的化學(xué)》(碩士生)、《化學(xué)生物學(xué)專題》(博士生)
《藥物的分子設(shè)計與新藥研究》(博士生)
碩士研究生招生:
無機(jī)化學(xué)(生物無機(jī)化學(xué)方向)、有機(jī)化學(xué)(生物有機(jī)化學(xué)方向)
博士研究生招生:
無機(jī)化學(xué)(生物無機(jī)化學(xué)、納米材料的合成與生物安全性)
科學(xué)研究與開發(fā)
主要研究方向:①硒與活性氮(RNS)在血管疾病、糖尿病發(fā)生發(fā)展中的作用及其機(jī)理;②無機(jī)納米材料的合成與生物安全性研究;③新藥制劑及功能食品的研究與開發(fā)。
目前主持在研項目:⑴國家自然科學(xué)基金(20671037):硒和活性氮對胰島素信號傳導(dǎo)系統(tǒng)的調(diào)控作用及機(jī)理;⑵973項目子課題(2006CB705606A):納米材料TiO2安全性解決方案的探索;⑶益聯(lián)醫(yī)藥有限公司(境外合成課題):降鈣素口腔噴霧劑的臨床前研究。
發(fā)表論文
在國內(nèi)外學(xué)術(shù)期刊發(fā)表論文100多篇,其中SCI論文60余篇,作為副主編出版有硒的專著1本,參編專著3本,代表性論文如下:
⒈Pingtang Zhao,Jinmin Wang,Guoe Cheng,and Kaixun Huang*. Fabrication of Symmetric
Hierarchical Hollow PbS Microcrystals via a Facile Solvothermal Process. Journal of Physical
Chemistry B. 2006,110,22400-22406.
⒉Guoe Cheng,Jinmin Wang,Xiangwen Liu,Kaixun Huang*. Self-Assembly Synthesis of
Single- Crystalline Tin Oxide Nanostructures by a Poly (acrylic acid) (PAA)-Assisted
Solvothermal Process. Journal of Physical Chemistry B. 2006,110,16208-16211.
⒊Qingzhi Wu,Kaixun Huang*. Protective effect of ebselen on cytotoxicity induced by
cholestane-3 beta,3 5 alpha,6 beta-triol in ECV-304 cells. Biochimica et Biophysica
Acta- molecular and cell biology of lipids. 2006,1761: 350u2013359.
⒋Chen-Xiao Zhang,Kai-Xun Huang*. Mechanism of apoptosis induced by a polysaccharide,
from the loach Misgurnus anguillicaudatus (MAP) in human hepatocellular carcinoma cells.
Toxicology and Applied Pharmacology. 2006,210: 236-245.
⒌Yili Ge,Hong Peng,Kaixun Huang*. 31P-NMR study on the autophosphorylation of
insulin receptor in the plasma membrane. Analytical and Bioanalytical Chemistry. 2006,
385⑸: 834u2013839.
⒍Rong Tang,Hongmei Liu,Tiebing Wang,Kaixun Huang*. Mechanisms of selenium inhibition
of cell apoptosis induced by oxysterols in rat vascular smooth muscle cells. Archives of
Biochemistry and Biophysics. 2005,441: 16u201324.
⒎Wen-xun Guo,Kai-xun Huang*,Rong Tang,Hui-bi Xu. Synthesis,characterization
of novel injectable drug carriers and the antitumor efficacy in mice bearing Sarcoma-180
tumor. Journal of Controlled Release. 2005,107: 513u2013522.
⒏Quan Chi,Tielin Wang,Kaixun Huang*. Effect of insulin nitration by peroxynitrite on
its biological activity. Biochemical and Biophysical Research Communications. 2005,
330: 791u2013796.
⒐Tang R,Huang KX*. Inhibiting effect of selenium on oxysterols-induced apoptosis
of rat vascular smooth muscle cells. Journal of Inorganic Biochemistry. 2004,98: 1678u20131685.
⒑Wu Q,Huang K*,and Xu H. Effects of long-term selenium deficiency on glutathione
peroxidase and thioredoxin reductase activities and expressions in rat aorta. Journal of
Inorganic Biochemistry. 2003; 94⑷: 301-6