主要研究方向為進化基因組學(xué)和生態(tài)基因組學(xué)，具體包括：

適應(yīng)性進化
物種形成
植物基因組進化
趨同進化
系統(tǒng)發(fā)育地理

1978.3-1982.1江西大學(xué)生物系，生物學(xué)專業(yè)，獲理學(xué)學(xué)士學(xué)位
1983.9-1986.7中山大學(xué)生物系，獲植物學(xué)碩士學(xué)位，導(dǎo)師張宏達
1987.9-1990.12中山大學(xué)生物系，獲植物學(xué)（植物分子系統(tǒng)學(xué)方向）博士學(xué)位，導(dǎo)師張宏達

1982.2-1983.9江西農(nóng)業(yè)大學(xué)牧醫(yī)系，助教
1986.7-1987.9中國科學(xué)院華南植物所，實習(xí)研究員
1990.12-1992.11中山大學(xué)生物系，講師
1992.11-1995.12中山大學(xué)生物系，副教授
1995.12-，中山大學(xué)生命科學(xué)學(xué)院，教授，博士生導(dǎo)師（1998）
1996.3-1997.3美國科羅拉多州立大學(xué)生物系，訪問教授
2000.4-2000.7韓國嶺南大學(xué)生物系，訪問教授
2000.9-2001.1美國哈佛大學(xué)標本館，訪問教授
2003.12-2004.4 美國芝加哥大學(xué)生態(tài)與演化系，訪問教授

本科生課程：
進化生物學(xué)
基因與基因組進化（逸仙學(xué)院）

研究生課程：
分子系統(tǒng)學(xué)

長期從事紅樹植物適應(yīng)性進化研究，致力于紅樹植物生態(tài)基因組學(xué)與物種形成模式研究。近年來集中在基因組水平探索潮間帶極端環(huán)境下紅樹植物進化和物種形成的基因組機制。發(fā)表SCI論文130余篇，部分論文發(fā)表在Nature,Molecular Biology and Evolution,PLoS Genetics,National Science Review,Global Change Biology,Molecular Ecology等期刊上。 2011年獲得國家自然科學(xué)二等獎，2002年和2008年兩次獲得教育部自然科學(xué)一等獎，1998年獲國家杰出青年基金資助，2001年獲求是杰出青年學(xué)者獎，2010年獲得丁穎科技獎，2017年獲美國植物學(xué)會終身榮譽會員“Corresponding Member”。

論文專著

Huang Y.,S. Shi*. 2002. Phylogenetics of Lythraceae sensu lato: a preliminary analysis based on chloroplast rbc L gene, psa A-ycf 3 spacer, and nuclear rDNA internal transcribed spacer (ITS) sequences. International Journal of Plant Sciences 163(2): 215-225.

Wu C-I.,S. Shi, Y. Zhang. 2004.A case for conservation. Nature 428: 213-214.

Shi S.*, Y. Huang, K. Zeng, F. Ten, H. He, J. Huang, Y. Fu*. 2005. Molecular phylogenetic analysis of mangroves: independent evolutionary origins of vivipary and salt secretion. Molecular Phylogenetics and Evolution 34(1): 159-166.

Lu J., T. Tang, H. Tang, J. Huang,S. Shi*, C-I. Wu*.2006.The accumulation of deleterious mutations in the rice genomes: A hypothesis on the cost of domestication. Trends in Genetics 22: 126-131.

Tang T., J. Lu, J. Huang, J. He, S. R. McCouch, Y. Shen, Z. Kai, M. D. Purugganan,S. Shi*, C-I. Wu*. 2006. Genomic variation in rice: Genesis of highly polymorphic linkage blocks during domestication. PLOS Genetics 2(11): e199.

Zhou R., K.Zeng, W. Wu, X. Chen, Z.Yang,S.Shi*, C-I.Wu. 2007. Population Genetics of Speciation in Nonmodel Organisms: I. Ancestral polymorphism in Mangroves.Molecular Biology and Evolution 24: 2746-2754.

Zhou R., S. Ling, W. Zhao, N.Osada, S. Chen, M. Zhang, Z. He, H. Bao, C. Zhong, B. Zhang, X. Lu, D.Turissini, N.C. Duke, J. Lu,S. Shi*, C-I. Wu*. 2011. Population genetics in non-model organisms: II. Natural selection in marginal habitats revealed by deep sequencing on dual platforms. Molecular Biology and Evolution 28: 2833-2842.

He Z., W. Zhai, H. Wen, T. Tang, Y. Wang, X. Lu, AJ. Greenberg, RR. Hudson, C-I. Wu*,S. Shi*. 2011. Two evolutionary histories in the genome of rice: the roles of domestication genes. PLOS Genetics 7: e1002100.

Guo Z., Y. Huang, Y. Chen, N. C. Duke, C. Zhong.,S. Shi*. 2016.Genetic discontinuities in a dominant mangroveRhizophora apiculata(Rhizophoraceae) in the Indo-Malesian region. Journal of Biogeography 43: 1856u20131868.

XuS., Z. He, Z. Guo, Z. Zhang, J. G. Wyckoff, A. Greenberg, C-I. Wu,S. Shi*. 2017. Genome-wide convergence during evolution of mangroves from woody plants. Molecular Biology and Evolution 34: 1008-1015.

YangM., Z. He,S. Shi*, C-I. Wu *. 2017. Can genomic data alone tell us whether speciation happened with gene flow? Molecular Ecology 26(11): 2845-2849.

YangM., Z. He, Y. Huang, L. Lu, Y. Yan, L. Hong, H. Shen, Y. Liu, Q. Guo, L. Jiang, Y. Zhang, A. J. Greenberg, R. Zhou, X. Ge, C-I. Wu,S. Shi*. 2017.The emergence of the hyper-invasive vine,Mikania micrantha(Asteraceae), via admixture and founder events inferred from population transcriptomics. Molecular Ecology 26(13): 3405-3423.

Xu S., Z. He, Z. Zhang, Z. Guo, W. Guo, H. Lyu, J. Li, M. Yang, Z. Du, Y. Huang, R. Zhou, C. Zhong, D. E. Boufford, M. Lerdau, C-I. Wu, N. C. Duke, The International Mangrove Consortium,S. Shi*. 2017. The origin, diversification and adaptation of a major mangrove clade (Rhizophoreae) revealed by whole genome sequencing.National Science Review4(5): 721-734.

GuoZ., X. Li, Z. He, Y. Yang, W. Wang, C. Zhong, A. Greenberg, C-I. Wu, N. C. Duke,S. Shi*. 2018. Extremely low genetic diversity across mangrove taxa reflects past sea level changes and hints at poor future responses.Global Change Biology,24:1741u20131748.

LyuH., Z. He, C-I. Wu,S. Shi*. 2018. Convergent adaptive evolution in marginal environments: unloading transposable elements as a common strategy among mangrove genomes, New Phytologists,217: 428u2013438.

He Z., X. Li, M. Yang, X. Wang, C. Zhong, N.C. Duke, C-I. Wu*,S. Shi*. 2019. Speciation with gene flow via cycles of isolation and migration: Insights from multiple mangrove taxa. National Science Review 10.1093/nsr/nwy078.