研究方向
1、 生物分子的化學(xué)修飾、組裝及仿生應(yīng)用
2、 生物催化與轉(zhuǎn)化
教育與工作經(jīng)歷
2015 年 06 月 — 至今,副教授,碩士生導(dǎo)師(化學(xué)工程)
2014 年 04 月 — 2015 年 03 月,美國(guó)伊利諾伊大學(xué)香檳分校,訪問(wèn)學(xué)者
2011 年 12月 — 2015 年 06 月,天津大學(xué)化工學(xué)院, 講師,碩士生導(dǎo)師(化學(xué)工程)
2008 年 09月 — 2011 年 07月,天津大學(xué) 化學(xué)工程 博士
2006 年 09月 — 2008 年 07月,天津大學(xué) 化學(xué)工程 碩士
2002 年 09月 — 2006 年 07月,天津大學(xué) 化學(xué)工程與工藝 本科
科研項(xiàng)目
國(guó)家級(jí)科研項(xiàng)目:
1、 國(guó)家自然科學(xué)基金(面上項(xiàng)目):多肽自組裝模擬酶的構(gòu)建、機(jī)理與應(yīng)用(21676191),項(xiàng)目負(fù)責(zé)人
2、 國(guó)家自然科學(xué)基金(青年基金):具有肌肽合成活性的新型印跡酶分子構(gòu)建及其穩(wěn)定化研究(21206113),項(xiàng)目負(fù)責(zé)人
3、 國(guó)家重大科學(xué)儀器設(shè)備開(kāi)發(fā)專項(xiàng):高關(guān)注度化學(xué)污染物檢測(cè)技術(shù)研究,項(xiàng)目負(fù)責(zé)人
省部級(jí)科研項(xiàng)目:
4、 天津市應(yīng)用基礎(chǔ)與前沿技術(shù)研究計(jì)劃項(xiàng)目:印跡脂肪酶分子的構(gòu)建、穩(wěn)定化及生物催化應(yīng)用研究(13JCQNJC09300),項(xiàng)目負(fù)責(zé)人
校級(jí)科研項(xiàng)目:
5、天津大學(xué)自主創(chuàng)新項(xiàng)目:酶的分子修飾及生物催化應(yīng)用,項(xiàng)目負(fù)責(zé)人
6、天津大學(xué)自主創(chuàng)新項(xiàng)目:基于分子印跡與雙親短肽自組裝構(gòu)筑高效人工模擬酶體系,項(xiàng)目負(fù)責(zé)人
論著專利
[19] Wang Mengfan, Lv Yuqi, Liu Xiaojing, Qi Wei*, Su Rongxin, He Zhimin Enhancing the activity of peptide-based artificial hydrolase with catalytic Ser/His/Asp triad and molecular imprinting.ACS Applied Materials & Interfaces. 2016, 8 (22): 14133u201314141
[18] Sun huaisheng, You shengping,Wang Mengfan*, Qi Wei*, Su Rongxin, He Zhimin. Recyclable strategy for the production of high-purity galacto-oligosaccharides by Kluyveromyces lactis.Journal of Agricultural and Food Chemistry,2016, 64 (28): 5679u20135685
[17] Tong Liping, Qi Wei*,Wang Mengfan*, Huang Renliang, Su Rongxin, He Zhimin. Tunable and visible structural colours produced by graphene oxide pseudo-one-dimensional photonic crystals.Small.2016, 12(25):3432
[16] Lan Xiaobo, Zhao Wenbin,Wang Mengfan*, Qi Wei*, Su Rongxin, He Zhimin. Preparation of Molecular Imprinted Photonic Crystal Sensor and Its Application in Determination of Phthalate Esters. Chinese Journal of Analytical Chemistry 2015, 43(4): 471-478
[15] Lv Yuqi,Wang Mengfan*, Qi Wei*, Su Rongxin, He Zhimin. Artificial Hydrolase Based on Short Peptides Self- and Co-assembly Nanofiber.Chemical Journal of Chinese Universities 2015, 36 (7): 1304-1309
[14] Wang Mengfan, Qi Wei*, Su Rongxin, He Zhimin. Advances in carrier-bound and carrier-free immobilized nanobiocatalysts.Chemical Engineering Science, 2015, 135, 21-32
[13] Mu Yangyang, Zhen Qiannan,Wang Mengfan*, Qi Wei*, Su Rongxin, He Zzhimin. Preparation and Thermal Kinetic Deactivation of Cross-linked Enzyme Aggregates of Penicillin Acylase. Chemical Journal of Chinese Universities-Chinese, 2014, 35(6): 1212-1218
[12] Wang Mengfan, GuoJian, Qi Wei*, Su Rongxin, He Zhimin. An effective and green method for the extraction and purification of aglyconeisoflavones from soybean. Food Science and Biotechnology, 2013, 22(3): 1-8
[11] Wang Mengfan, Mu Yangyang, Qi Wei*, Su Rongxin, He Zhimin. Intensive Protein Digestion Using Cross-linked Trypsin Aggregates in Proteomics Analysis.ChemPlusChem, 78 (5): 407u2013412
[10] Wang Mengfan, Zhang Shuaishuai, Qi Wei*, Liu Zhaohui, Wu Weina, Su Rongxin, He Zhimin. Puri?cation, characterization, and production of b-mannanase from Bacillus subtilis TJ-102 and its application in gluco-mannooligosaccharides preparation.European Food Research and Technology. 2013, 237(3): 399-408
[9] Zhen Qiannan; Wang Mengfan (co-first author); Qi, Wei*; Su, Rongxin; He, Zhimin.Preparation of β-mannanase CLEAs with macromolecular cross-linker.Catalysis Science & Technology. 2013, 3, 1937-1941
[8] Geng Bo,WangMengfan(co-first author), Qi Wei*, Su Rongxin,He, Zhimin. Cinnamyl acetate synthesis by lipase-catalyzed transesterification in a solvent-free system.Biotechnology and Applied Biochemistry, 59 (4): 270-275.
[7] Wang Mengfan, JiaChenxi, Qi Wei*, Yu Qingxin, PengXin, Su Rongxin, He Zhimin. Porous-CLEAs of papain: Application to enzymatic hydrolysis of macromolecules. Bioresource Technology, 2011, 102(3), 3541-3545.
[6] Wang Mengfan, Qi Wei*, JiaChenxi, RenYufei, Su Rongxin, He Zhimin. Enhancement of activity of cross-linked enzyme aggregates by a sugar-assisted precipitation strategy: Technical development and molecular mechanism. Journal of Biotechnology, 2011, 156(1), 30-38.
[5] Wang Mengfan, Qi, Wei*, Yu Qingxin, Su Rongxin, He Zhimin. Cross-linking enzyme aggregates in the macropores of silica gel A practical and efficient method for enzyme stabilization. Biochemical Engineering Journal, 52(2-3), 2010, 168-174.
[4] Wang Mengfan, Qi Wei*, Yu Qingxin, Su Rongxin, He Zhimin. Kinetically controlled enzymatic synthesis of dipeptide precursor of l-alanyl-l-glutamine.Biotechnology and Applied Biochemistry, 2011, 58(6), 449-455.
[3] Wang Mengfan, Qi Wei*, Su Rongxin, He Zhimin. Preparation and Properties of Cross-linked Enzyme Aggregates of Papain.Chemical Journal of Chinese Universities, 2010, 31(9), 1774-1779.
[2] Wang Mengfan, Qi Wei*, Su Rongxin, He Zhimin. Advances in Cross-Linked Enzyme Aggregates Progress In Chemistry, 2010, 22(1), 173-178.
[1] Wang Mengfan, JiaChenxi, Qi Wei*, He Zhimin. Preparation and properties of cross-linked enzyme aggregation of trypsin.ActaChimicaSinica, 2008, 66(16), 1929-1934.
獲得獎(jiǎng)勵(lì)
入選2013年度“北洋學(xué)者青年骨干教師計(jì)劃”
獲得2013年度天津市自然科學(xué)二等獎(jiǎng):蛋白質(zhì)和多糖結(jié)構(gòu)解析與酶解轉(zhuǎn)化利用基礎(chǔ)研究,排名第五