研究領(lǐng)域
主要從事有機(jī)藥物小分子的合成和雜環(huán)化合物的合成工作。研究方向主要有雜環(huán)有機(jī)化合物合成、催化有機(jī)合成和綠色有機(jī)合成。
代表性論文
Quan, Z.-J.; Ren, R.-G. Da, Y.-X.; Zhang, Z.; Jia, X.-D.; Wang, X. N-Alkoxymethylation of heterocyclic compounds with diethyl phosphite via cleavage of P-O bond. Tetrahedron, 2011, 67, 2462.
Quan, Z.-J.; Ren, R.-G. Da, Y.-X.; Zhang, Z.; Jia, X.-D.; Yang, C.-X.; Wang, X.-C. One-Pot Two-Step Synthesis of N3-Functionalized 3,4-Dihydropyrimidinones in the Presence of TMSCl. Heterocycles 2010, 81, 1827.
Quan, Z.-J.; Da, Y.-X.; Zhang, Z.; Wang, X.-C. PS?PEG?SO3H as an efficient catalyst for 3,4-dihydropyrimidones via Biginelli reaction. Catal. Commun. 2009, 10, 1146.
Quan, Z.-J.; Wei, Q.-B.; Ma, D.-D.; Da, Y.-X.; Wang, X.-C.; Shen, M.-S. General and Green Synthesis of C-6 Sulfonylmethyl 4-Aryl-3,4-dihydropyrimidinones in Water. Synth. Commun. 2009, 39, 2230.
Quan, Z.-J.; Zhang Z.; Wang, J.-K.; Wang, X.-C.; Liu, Y.-J.; Ji, P.-Y. Efficient Synthesis of 5H-Thiazolo[3,2-a]pyrimidines from Reactions of 3,4-Dihydropyrimidine-thiones with α-Bromoacetone in Aqueous Media. Heteroatom Chem. 2008, 19, 149.
權(quán)正軍, 張彰，王喜存. Biginelli 3,4-二氫嘧啶-2-酮衍生物的合成研究新進(jìn)展。有機(jī)化學(xué)， 2009, 29, 876.
Wang, X.-C.; Quan, Z.-J. A practical and green approach towards synthesis of N3 substituted dihydropyrimidinones: Using Aza-Michael addition reaction catalyzed by KF/Al2O3. Bioorg. Med. Chem. Lett. 2006, 16, 4592.
Wang, X.-C.; Quan, Z.-J. Michael additions of dihydropyrimidines and 2-amino-1,3,4-thiadiazoles to α, β-ethylenic compounds: Using polyethylene glycols as a green reaction media. Tetrahedron 2007, 63, 8227.