錢坤喜——國際著名心臟泵專家
無內(nèi)容
專家信息:
錢坤喜,男,1944年生,籍貫:廣東省,教授、博士生導(dǎo)師,F(xiàn)任江蘇大學(xué)生物醫(yī)學(xué)工程研究所所長。
教育及工作經(jīng)歷:
1968年畢業(yè)于復(fù)旦大學(xué)數(shù)學(xué)系力學(xué)專業(yè)。
1980年畢業(yè)于江蘇大學(xué)流體機(jī)械專業(yè)研究生班。
1981~~1983年赴德國柏林自由大學(xué)進(jìn)修人造心臟泵。
1984~~1988年在上海第二醫(yī)科大學(xué)主持有關(guān)人工心臟研究的國家自然科學(xué)基金項(xiàng)目。
1989~~1991年在德國亞琛大學(xué)合作研究。
1992年被美國猶太大學(xué)聘為科技顧問。
1993~~1994年以大陸杰出科技人士身份由臺(tái)灣“國科會(huì)”延攬至臺(tái)灣大學(xué)醫(yī)學(xué)院主持大型整合性研究計(jì)劃。
1995年回上海第二軍醫(yī)大學(xué)繼續(xù)研究。
1996年起任江蘇大學(xué)生物醫(yī)學(xué)工程研究所所長、教授、博士生導(dǎo)師。
科學(xué)研究:
研究方向:
主要從事人造心臟泵的研究。
承擔(dān)的科研項(xiàng)目情況:
“九五”期間,主持國家“九五”科技攻關(guān)項(xiàng)目一項(xiàng)、國家自然科學(xué)基金項(xiàng)目二項(xiàng)、國家教委博士點(diǎn)基金項(xiàng)目一項(xiàng)、江蘇省科委“九五”科技攻關(guān)項(xiàng)目一項(xiàng),其中國家及江蘇省“九五”攻關(guān)項(xiàng)目已通過科技部組織的專家鑒定和驗(yàn)收。
科研成果:
1.1983年研制成功世界上第一個(gè)全植入式離心泵。
2.1984年首次實(shí)現(xiàn)人工心臟試驗(yàn)動(dòng)物的自由走動(dòng)。
3.1986年率先解決旋轉(zhuǎn)血泵產(chǎn)生搏動(dòng)流的世界性難題。
4.1987年研制成功世界上第一個(gè)能產(chǎn)生搏動(dòng)流的低溶血離心泵。
5.1987年研制成葉輪全人工心臟即旋轉(zhuǎn)型雙心室輔助器并應(yīng)用于動(dòng)物試驗(yàn),其結(jié)果在國際會(huì)議發(fā)表時(shí)曾引起震動(dòng),被國外同行稱之為“新一代的人工心臟”。
6.創(chuàng)立旋轉(zhuǎn)式心臟泵葉輪葉片的三元解析設(shè)計(jì)方法,該方法被美國猶太大學(xué)醫(yī)工所所長Olsen教授贊譽(yù)為“完美的”和“可信的”。
7.在完成國家“九五”科技攻關(guān)項(xiàng)目時(shí),研制出能長期使用的機(jī)械軸承離心泵,與此同時(shí),試制成永磁懸浮離心泵。
8.1992年微型化至100克左右,比美國同類型裝置輕一半,被臺(tái)灣媒體稱之為“錢氏人工心臟”。
9.1993年發(fā)現(xiàn)血液在一定條件下是良導(dǎo)體,并研制超導(dǎo)電磁人工心臟(磁流體動(dòng)力泵),國外專家稱之為“ 21世紀(jì)的人工心臟”。結(jié)論達(dá)到國際先進(jìn)水平,《人民日?qǐng)?bào)》2001年1月10日予以報(bào)道。
10.1994年在動(dòng)物試驗(yàn)中達(dá)到小公牛存活 62天的記錄,1996年應(yīng)用到臨床。
目前,人工心臟的耐久性問題已獲得突破,使用壽命已經(jīng)延長到一年以上,正在研制中的無源磁浮葉輪泵模型,正處于試驗(yàn)室研究階段,標(biāo)志著人工心臟研究達(dá)到了新的里程碑。
發(fā)明專利:
1 )2007-08-15 應(yīng)用于透平機(jī)的永磁懸浮軸承 錢坤喜 江蘇大學(xué)
2 )2007-08-15 永磁懸浮軸承離心泵 錢坤喜 江蘇大學(xué)
3 )2003-09-24 無源磁浮實(shí)現(xiàn)穩(wěn)定平衡的方法及用途 錢坤喜 江蘇大學(xué)
4 )2005-01-05 人造心臟瓣膜泵 錢坤喜 江蘇大學(xué)
5 )2005-01-05 無源磁浮永久性心室輔助葉輪血泵 錢坤喜 江蘇大學(xué)
6 )2004-03-03 一種磁力減載高速列車 錢坤喜 江蘇大學(xué)
論文專著:
代表性論文:
1.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y.,Feng,Z.G.,Li,L.“Magnetic spring and magnetic bearing.”IEEE Trans. Magnetics. 391(1):559-561,2003
2.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y.“World-first implantable aortic valvo-pump with sufficient hemo-dynamic capacity.” J Med.Eng.Tech.29(6):302-304, 2005
3.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y.“World-smallest LVAD with 27 g weight, 21 mm OD and 5 l min-1 flow with 50 mmHg pressure increase.”J Med Eng Technol. May-Jun;31(3):181-4. 2007
4.Qian Kunxi, Xu Zihao, Wang Hao, “Relation between Minimal Speed and Rotational Inertia of Stable PM Maglev Bearing Rotator.” The Twelfth International Symposium on Magnetic Bearings (ISMB 12) Wuhan, China, August 22-25, 314-319.2010,
5.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “New concepts and new design of permanent maglev rotary artificial heart blood umps.” J Med. Eng. Physics.28(4): 383-388, 2006
近十年發(fā)表論文目錄:
1. Qian,K.X “20 yearsu2019 efforts to develop a Chinese artificial heart.” ICMT(International Conference of Medical Technology),Houston, 2002
2. Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y.“New concept of impeller pumps with magnetic bearing”. J. Drainage and Irrigation Machinary.20(6):7-9, 2002
3. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Improved design of permanent maglev impeller assist heart.” J.Biomed.Eng(Chendou)., 19(4):593-595,2002
4. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Permanent maglev stability: new concept, new design and new applications. ” J. Jiangsu Uni.,24(1):5-9,2003
5. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y.,Feng,Z.G.,Li,L. “Super-low-noise permanent maglev propeller for ships and boats. ”J Machine Design & Research.19(1):82-84, 2003
6. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y.,Feng,Z.G.,Li,L. “Magnetic spring and magnetic bearing. ”IEEE Trans. Magnetics. 391(1):559-561,2003
7. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “The realization of a small rotor magnet and large air gap motor with sufficient torque and high efficieny.”ESAO,2003
8. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A novel permanent maglev LVAD with simplicity and pulsatility: most problems of blood pumps have been solved.”ESAO,2003
9. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Applications of neutral network for computing pump flow and pressure.”ESAO,2003
10.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A novel permanent magnetic bearing and its anti-wear effect in impeller TAH. ”J. Progress in Natural Science.13(4): 304-306, 2003
11. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A novel permanent maglev impeller TAH: most requirements on blood pumps have been satisfied.” J .Biomaterials Applications. 18(1):53-62,2003
12.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Axial reciprocation of rotating impeller for anti-thrombogenicity along the bearing in centrifugal pump ”Chn .J. General practice Med.Res.No.6.PP.5-6,2003
13.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A novel permanent rotary total artificial heart with permanent maglev impellers.” ASAIOu201903,Artificial organs 27(4):300, 2003
14.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Influence of rare-earth PM brush-less motor rotor magnet size and air-gap on the output torque and efficiency. ”J Micro & Special Electrical Machines. 31(3):17-18,2003
15. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A permanent impeller TAH for permanent circulatory support. ”Chn Clinical Medicine Monthly .2(4): 295-297.2003
16. Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “A new passive magnetic bearing and its applications in durable impeller TAH.” J. Machine Design and Research. 19(3):46-47,2003
17. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Development of permanent artificial heart. ”J Chn Med 4,2003
18.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Permanent maglev LVAD with simplicity and pulsatility: most problems of blood pumps have been solved. ” International J Artificial Organs. Vol.26(7):582,2003
19.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Applications of neutral network for computing pump flow and pressure. ” International J Artificial Organs. Vol.26(7):586,2003
20. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “The realization of a small rotor magnet and large air gap motor with sufficient torque and high efficiency. ”International J Artificial Organs.Vol.26(7):620, 2003
21.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A new approach for improving anti-thrombogenicity in centrifugal pump.” J Biomed. Engineering(Chendou).20(3):534-536,2003
22.Qian KX et al “Effect of impeller vane number and angles on pump hemolysis.” J Biomed. Eng(Chendou)..20(4):605-7,2003
23. Qian, K.X., et al. “Factors affecting the stability of passive maglev impeller in centrifugal pump.” XXXI. Annual Congress of ESAO, Warsaw, Poland, Sept.8-11, 2004
24. Qian, K.X., et al. “25mm diameter and 40 gram weight implantable aortic valvo-pump with sufficient hemo-dynamic capacity.” XXXI. Annual Congress of ESAO, Warsaw, Poland, Sept.8-11, 2004
25. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “PIV reveals the effect of vane number and angel as well as flow rate on pump hemolysis in centrifugal pump.” 50th Annual Conference of ASAIO, Washington, DC, June17-19, 2004
26.Qian,K.X.,Wan,F.K.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Eccentric distance and vibration amplitude of permanent maglev impeller in centrifugal pump.” 50th Annual Conference of ASAIO, Washington, DC, June17-19, 2004
27.Qian,K.X.,Wang,F.Q.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Streamlined design of impeller and its CFD certification in centrifugal pump.” 50th Annual Conference of ASAIO, Washington, DC, June17-19, 2004
28.Qian,K.X.,Wang,D.F., Topaz,S.,Zeng,P.,Ru,W.M., Yuan,H.Y. “First prototype development of aortic valvo-pump.” 50th Annual Conference of ASAIO, Washington, DC, June17-19, 2004
29.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Measurement of eccentric distance and vibration amplitude of permanent maglev impeller of centrifugal pump.” J Jiangsu University(Natural Science Edition).25(1): 60-63, 2004
30. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Research and development of a physiologic cardiovascular circulatory model.” J. Jiangsu University(Natural Science Edition).26(6):521-524, 2004
31. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Development of 25mm aortic valvo-pump.” J Jiangsu University(Natural Science Edition).26(4): 361-363 , 2005
32. Qian,K.X., Wang,D.F., Topaz,S., Zwischenberg,J.B. “Implantable aortic valve annular pump with sufficient hemo-dynamic capacity for total left ventricular support.” 51th Annual Conference of ASAIO, Washington,DC, June9-11,2005
33.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “ Development of 21mm aortic valvo-pump.” Shanghai J Biomed. Eng.26(3):160-162,2005
34. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “A novel rotary LVAD with passive magnetic bearings.” J Med. Eng. Tech.29(5): 235-237,2005
35.Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Position detection of permanent maglev impeller in centrifugal heart pump.” Chn. J Mech. Eng.41(1): 181-183,2005
36. Qian,K.X., Wang,D.F., Topaz,S., Zwischenberg,J.B. “The prototype of trans-ventricular LVAD with rolling bearing and a purge system: Toward durability and erformance.”51th Annual Conference of ASAIO, Washington ,DC, June9-11,2005
37. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Development of permanent maglev motor and its applications in artificial hearts.” J Micro and Special Motors.33(11):9-11,2005
38. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “World-first implantable aortic valvo-pump with sufficient hemo-dynamic capacity. ”J Med.Eng.Tech.29(6):302-304, 2005
39. Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Development of a trans-apical and imtra-ventrcular pump.” Chn. J. Thoracic and Cardiovascular Surgery. 21(5):311, 2005
40. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Present situation and prospects of artificial heart pumps in Jiangsu University.” Chn. J. Medical Instruments.29(4):238-240,2005
41. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “Use of aortic valvo-pumps placed in valve annulus for long-term left ventricular assist.” J.ASAIO. 51(6):736-738, 2005
42.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Prototypes of axially driven permanent maglev centrifugal pump with streamlined impeller.” J. Jiangsu Univ.(Natural Science Edition).26(6):510-513,2005
43. Qian,K.X.,Zeng,P.,Ru,W.M., Yuan,H.Y. “New concepts and new design of permanent maglev rotary artificial heart blood pumps.” J Med. Eng. Physics.28(4): 383-388, 2006
44.Qian, K.X., Wan FK et al:“Study on stability of permanent maglev in artificial heart blood pumps.” J .Med.Eng.Tech. 30(2):78-82,2006
45.Qian,K.X“An implantable aortic valvo-pump for destination therapy.” J of Cardiovascular Engineering: An International J.6(1):40-42,2006
46.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Computerized fluid dynamics verified the advantages of streamlined impeller design in improving the flow patterns and anti-hemolysis properties in centrifugal pumps.”J Med. Eng .Tech.30(6):353-357, Nov.-Dec.,2006
47.Qian, K.X., et al: “Permanent maglev centrifugal pump stabilized by gyro-efect.” J mech. Research and Design.22(4):89-90,2006
48.Qian, K. X., et al: “Back-flow of aortic valvo-pump.”J Jiangsu Univ.(Natural Science Edition).27(5):434-436,2006
49. Qian, K. X, et al: “Original study of a long-term aortic valve pump of 23mm outer diameter, weighing 31g.” Clinical J of thoracic and cardiovascular surgery of china. 13(3):173-175,2006
50.Qian,K.X.: “Aortic valvo-pump and intraventicular axial pump.” International Conference of Regeneration Medicine. Beijing Fu-wei Hospital,Octorber,2006
51. Qian,K.X.: “Gyro-effect makes unstable permanent maglev impeller heart pump stabilized.” International Conference of Regeneration Medicine. Beijing Fu-wei Hospital,Octorber,2006
52. Qian,K.X., et al: “Design concept and experimental results of a permanent maglev rotary LVAD.” Chn. J BME.25(4):510-512,2006
53.Qian,K.X., Zeng,P., Ru,W.M., Yuan,H.Y. “An improved design of axially driven permanent maglev centrifugal pump with streamlined impeller.”J Med. Eng. Tech.. Jay-Jun;31(3):170-4. 2007
54.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “Novel totally implantable trans-ventricular and cross-valvular cannular pump with rolling bearings and purge system for recovery therapy.”J Med Eng Technol. Jan-Feb;31(1):10-3. J Med.Eng.Tech 2007
55.ian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y. “PIV pictures of stream field predict haemolysis index of centrifugal pump with streamlined impeller.”J Med Eng Technol. Jul-Aug;31(4):239-42. J Med.Eng.Tech. 2007 J. Jiangsu Univ.(Natural Sience Edition).
56.Qian,K.X.: “Investigation on applying passive maglev bearings in impeller heart pumps.” The Annual Joint Conference of Chinese BME. Xi-an Jiao-Tong University ,April 2007
57.Qian,K.X.,Zeng,P.,Ru,W.M.,Yuan,H.Y.“World-smallest LVAD with 27 g weight, 21 mm OD and 5 l min-1 flow with 50 mmHg pressure increase.”J Med Eng Technol. May-Jun;31(3):181-4. 2007
58.Qian KX: “Recent achievements in developing mini axial and maglev radial blood pumps.” World Symposium of Chinese Scientists. Bangkok, July, 2007
59.Qian,K.X., et al: “Gyro-effect stabilized unstable permanent maglev centrifugal pump” J Cardiovascular Engineering: An International J. Mar;7(1):39-42.. 2007
60.Qian KX. “Artificial Heart Rejects High Tech? Lessens Learnt from Non-pulsatile VAD with Straight Impeller Vanes.”O(jiān)pen Biomed Eng J. Jul 17;1:35-7. 2007
61.Qian KX. “One thousand dollar assist heart pump for patients from developing countries.”O(jiān)pen Biomed Eng J Jun 28;1:11-2. . 2007
62. Qian KX “A mini axial and a permanent maglev radial heart pump.” Open Biomed Eng J. May 31;1:1-3. 2007
63.Qian KX: “Use of passive magnetic bearings in permanent maglev centrifugal pumps.” Proc. Biomed. Eng. Informatics, Shanghai, 2008
64.Qian KX: “Artificial heart rejects high Tech? Lessens learnt from non-pulsatile VAD with straight impeller vanes,” Proc. Biomed. Eng. Informatics, Shanghai,2008
65.Qian KX: “Novel connecting conduit-free and bypass circuit-less mini LVADs for reducing thrombosis risk”, Proc. Bioinformatics and Biomedical Engineering, Shanya, 2008
66.Qian KX:“Regurgitation of a mini axial pump with closed impeller used as a valvo-pump”, Proc. Bioinformatics and Biomedical Engineering, Shanya,2008
67.Qian KX: “Gyro-effect and Earnshawu2019s Theorem: Stable and unstable equilibrium for rotary and stationary permanent magnetic levitators”, Proc. Bioinformatics and Biomedical Engineering, Shanya,2008
68.Qian Kun-xi:“Artificial heart—non-pulsatile ventricular assist device with straight impeller vanes.” Journal of Clinical Rehabilitative Tissue Engineering Research, June 25, Vol.13, No.26, 2009
69. Qian Kun-xi:“Connecting conduit-free and bypass circuit-less mini LVADs eliminate the most likely sites of thrombosis.” Health, Vol.1, No.1,31-34. 2009
70.Qian kun-xi:“ Study on regurgitation of a bearing-less mini axial aortic valvo-pump with closed impeller.” Health, Vol.1, No.3, 173-175,2009
71.Qian Kunxi, Xu Zihao, Wang Hao, “Relation between Minimal Speed and Rotational Inertia of Stable PM Maglev Bearing Rotator.” The Twelfth International Symposium on Magnetic Bearings (ISMB 12) Wuhan, China, August 22-25, 314-319.2010,
72.Qian KX, Lu MF, Xu ZH, Wang H: “A Novel PM Bearing and Its Application in Permanent Maglev Turbine Machine.” The Twelfth International Symposium on Magnetic Bearings (ISMB 12) Wuhan, China, August 22-25,, 248-253, 2010