人物經(jīng)歷
2016.07-至今 四川大學生物治療國家重點實驗室研究員
2013.08-2016.06美國加州大學伯克利分校博士后
2011.10-2013.07美國NIH訪問學者
2006.09-2011.07清華大學博士
2002.09-2006.07山東大學學士
科研方向
主要以結(jié)構(gòu)生物學的方法研究細胞凋亡、細胞自噬的的分子機制，探索病原劫持哺乳動物細胞自噬分子機器的機制。
著述成果
代表性文章
1:Qi S, Kim do J, Stjepanovic G, Hurley JH.Structure of the Human Atg13-Atg101?HORMA Heterodimer: an Interaction Hub within the ULK1 Complex. Structure. 2015 Oct 6;23(10):1848-57. 2:Qi S, O’Hayre M, Gutkind JS, Hurley JH. Insights into β2-adrenergic receptor binding from structures of the N-terminal lobe of ARRDC3. Protein Sci. 2014 Dec;23(12):1708-16. 3:Qi S, O’Hayre M, Gutkind JS, Hurley JH. Structural and biochemical basis for ubiquitin ligase recruitment by arrestin-related domain-containing protein-3 (ARRDC3). J Biol Chem. 2014 Feb 21;289(8):4743-52. 4: Huang W, Jiang T, Choi W, Qi S, Pang Y, Hu Q, Xu Y, Gong X, Jeffrey PD, Wang J, Shi Y. Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev. 2013 Sep 15;27(18):2039-48. 5: Deng D, Yin P, Yan C, Pan X, Gong X, Qi S, Xie T, Mahfouz M, Zhu JK, Yan N, Shi Y. Recognition of methylated DNA by TAL effectors. Cell Res. 2012Oct;22(10):1502-4. 6:Qi S, Pang Y, Hu Q, Liu Q, Li H, Zhou Y, He T, Liang Q, Liu Y, Yuan X, Luo G, Li H, Wang J, Yan N, Shi Y. Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell. 2010 Apr30; 141(3):446-57. |