人物經(jīng)歷
學(xué)習(xí)經(jīng)歷
| 1996.09-2000.07 | 清華大學(xué)化學(xué)系化學(xué)專業(yè) | 理學(xué)學(xué)士 |
| 2000.09-2005.07 | 清華大學(xué)化學(xué)系分析化學(xué) | 理學(xué)博士 |
工作履歷
| 2005.08u20132012.12 | 清華大學(xué)化學(xué)系 | 講師，副教授 |
| 2016.01u20132020.12 | 清華大學(xué)化學(xué)系 | 長(zhǎng)聘副教授 |
| 2020.12u2013至今 | 清華大學(xué)化學(xué)系 | 長(zhǎng)聘教授 |
| 2013.01u2013至今 | 國(guó)家中醫(yī)藥管理局中藥化學(xué)三級(jí)實(shí)驗(yàn)室 | 主任 |
| 2019.01u2013至今 | 清華大學(xué)中藥研究院 | 副院長(zhǎng) |
| 2015.04u2013至今 | 清華大學(xué)化學(xué)系 | 黨委書記 |
社會(huì)任職
| 中國(guó)醫(yī)藥生物技術(shù)協(xié)會(huì)藥物分析分會(huì) | 秘書長(zhǎng) |
| 中國(guó)分析測(cè)試協(xié)會(huì)青年學(xué)術(shù)委員會(huì) | 副主任委員 |
| 中國(guó)中藥協(xié)會(huì)中藥產(chǎn)品開發(fā)與培育專業(yè)委員會(huì) | 副主任委員 |
| 中國(guó)藥理學(xué)會(huì)分析藥理學(xué)專業(yè)委員會(huì) | 委員 |
| 北京理化分析測(cè)試技術(shù)學(xué)會(huì) | 副理事長(zhǎng)兼青委會(huì)理事長(zhǎng) |
| 《藥物分析雜志》、《世界科學(xué)技術(shù)-中醫(yī)藥現(xiàn)代化》、《分析試驗(yàn)室》、《分析儀器》 | 編委 |
主要成就
科研綜述
以微流控芯片及其與質(zhì)譜、光譜聯(lián)用分析技術(shù)為基礎(chǔ)，發(fā)展生命分析與藥物分析新方法，開發(fā)生物醫(yī)用新材料新器件，發(fā)明器官類器官芯片新模型，致力于服務(wù)國(guó)家藥品質(zhì)量與安全、新藥創(chuàng)制以及中藥現(xiàn)代化研究與開發(fā)。近年來(lái)重點(diǎn)聚焦于器官類器官芯片、單細(xì)胞亞細(xì)胞分析及基于質(zhì)譜的多組學(xué)分析等。曾主持完成國(guó)家重大科技專項(xiàng)第一個(gè)微流控芯片藥物研發(fā)關(guān)鍵技術(shù)項(xiàng)目，在器官芯片核心關(guān)鍵技術(shù)及血管、肝、腎、腸等器官芯片模型研究方面取得重要進(jìn)展。2016-2020年間以第一發(fā)明人申請(qǐng)發(fā)明專利16項(xiàng)（授權(quán)8項(xiàng)），以通訊作者在Nat. Protoc., Adv. Mater., Anal. Chem., Lab Chip等重要學(xué)術(shù)期刊上發(fā)表SCI論文59篇（14篇IF>10）。工作以來(lái)累計(jì)發(fā)表SCI論文180余篇，Web ofScience引用5000余次，發(fā)明專利30余項(xiàng)。部分研究成果已在制藥企業(yè)、臨床醫(yī)院得到廣泛應(yīng)用，曾合作獲得國(guó)家科技進(jìn)步二等獎(jiǎng)3項(xiàng)。
獎(jiǎng)勵(lì)榮譽(yù)
2018 世界中醫(yī)藥學(xué)會(huì)聯(lián)合會(huì)中醫(yī)藥國(guó)際貢獻(xiàn)獎(jiǎng)-科技進(jìn)步二等獎(jiǎng)（2/10）
2016 國(guó)家科技進(jìn)步二等獎(jiǎng)（3/10）
2015 中華中醫(yī)藥學(xué)會(huì)科學(xué)技術(shù)進(jìn)步一等獎(jiǎng)(3/15)
2014 國(guó)家科技進(jìn)步二等獎(jiǎng)(8/10)
2013 廣西科技進(jìn)步二等獎(jiǎng)（6/10）
2012 北京市科技進(jìn)步二等獎(jiǎng)（4/10）
2007 國(guó)家科學(xué)技術(shù)進(jìn)步二等獎(jiǎng)(7/10)
學(xué)術(shù)成果
近年來(lái)發(fā)表的論文(Recent Publications)：
1. Xie RX, Liang Z, Ai YJ, Zheng WC, XiongJL, Xu PD, Liu YP, Ding MY, Gao JY, Wang Jiaping, and?Liang QL*. Composable microfluidic spinning platforms for facileproduction of biomimetic perfusable hydrogel microtubes.?Nature Protocols?2020, doi.org/10.1038/s41596-020-00442-9.
2. Xie RX, Korolj A, Liu C, Song X, Lu R,Zhang BY, Ramachandran A,?Liang QL*?and Radisic M*. h-FIBER: Microfluidictopographical hollow fiber for studies of glomerular filtration barrier.?ACS Central Science?2020, 6, 903-912.
3. Xie RX, Zheng WC, Guan LD, Ai YJ and?Liang QL*.?Engineering of Hydrogel Materialswith Perfusable Microchannels for Building Vascularized Tissues.?Small?2020, 16(15),?1902838.
4. Ai YJ, Xie RX, Xiong JL and?Liang QL*.?Microfluidics forBiosynthesizing: from Droplets and Vesicles to Artificial Cells.?Small?2020,16(9),1903940.
5. Xiong Jl, Xie RX, Wang Y, Wang CL, Ai YJ,Zheng WC, Ding MY, Gao JY, Wang JP, and?Liang QL*. Nitrite-ResponsiveHydrogel: Smart Drug Release Depending on the Severity of the NitricOxide-Related Disease.?ACS Applied Materials & Interfaces?2020, 12, 51185
6. Li JF, Liu L, Ai YJ, Liu Y, Sun HB* and?Liang QL*.?Self-Polymerized Dopamine-Decorated Au NPs and Coordinated with Fe-MOF asa Dual Binding Sites and Dual Signal-Amplifying Electrochemical Aptasensor forthe Detection of CEA.?ACS AppliedMaterials & Interfaces?2020, 12(5), 5500-5510
7. Ai YJ, Hu ZN, Liu L, Zhou JJ, Long Y, LiJF, Ding MY, Sun HB* and?Liang QL*.Magnetically Hollow Pt Nanocages with Ultrathin Walls as a Highly IntegratedNanoreactor for Catalytic Transfer Hydrogenation Reaction.?Advanced Science?2019, 6(7), 1802132.
8. Wang Y, Shao ZX, Zheng WC, Xie YY, Luo GA,Ding MY and?Liang QL*.?A 3D constructof the intestinal canal with wrinkle morphology on a centrifugation configuringmicrofluidic chip.?Biofabrication?2019, 11 (4), 045001.
9. Ai YJ, Zhang F, Wang CL, Xie RX and?Liang QL*.?Recent progress inlab-on-a-chip for pharmaceutical analysis and pharmacological/toxicologicaltest.?TrAC-Trends in Analytical Chemistry?2019, 117, 215-230.
10. Xie RX, Xu PD, Liu YP, Li LL, Luo GA, Ding MY and?Liang QL*. Necklace-LikeMicrofibers with Variable Knots and Perfusable Channels Fabricated by anOil-Free Microfluidic Spinning Process.?Advanced Materials?2018, 30, 1705082.
11. Zhang F, Xiong LG, Ai YJ, Liang Z and?Liang QL*. Stretchable Multi-responsive Hydrogel withActuatable, Shape memory and Self-healing Properties.?Advanced Science?2018, 5, 1800450.
12. Li LL, Li YQ, Shao ZX, Luo GA, Ding MY and?Liang QL*. Simultaneous Assay of Oxygen-Dependent Cytotoxicity and Genotoxicityof Anticancer Drugs on an Integrated Microchip.?Analytical Chemistry?2018,?90(20), 11899-11907.
13. Ma LD, Wang YT, Wang JR, Wu JL, Meng XS, Hu P, Mu X,?Liang QL*?and Luo GA*. Design and Fabrication of a Liver-on-a-chip Platformfor Convenient, Highly Efficient, and Safe in Situ Perfusion Culture of 3D HepaticSpheroids.?Lab on a Chip?2018, 18, 2547 -2562.
14. Yang SH, Zhang FF,?Liang QL*?and Wang ZH*.A Three-Dimensional Graphene-Based Ratiometric Signal Amplification Apta sensorfor MUC1 Detection.?Biosensors & Bioelectronics?2018, 120, 85-92.
15. Yang SH, Zhang FF, Wang ZH* and?Liang QL*. A Graphene Oxide-based Label-free ElectrochemicalAptasensor for the Detection of Alpha-fetoprotein.?Biosensors & Bioelectronics?2018, 112, 186-192.
16. Ai YJ, He MQ, Zhang F, Long Y, Li YZ, Han Q, Ding MY, Sun HB* and?Liang QL*. Metallo-supramolecular PolymerEngineered Porous Carbon Framework Encapsulated Stable Ultra-smallNanoparticles: a General Approach to Construct Highly Dispersed Catalysts.?Journalof Materials Chemistry A?2018, 6, 16680-16689.
17. Long Y, Han Q, Yang ZQ, Ai YJ, Sun SA, Wang Y,?Liang QL*?and Ding MY*. A Novel Solvent-free Strategy for the Synthesis ofBismuth Oxyhalides.?Journal of Materials Chemistry A?2018, 6, 13005-13011.
18. Xu PD, Xie RX, Liu YP, Li LL, Luo GA, Ding MY and?Liang QL*. Bioinspired Microfibers with Embedded Perfusable Helical Channels.?Advanced Materials?2017, 29, 1701664.
19. Zhou BJ, Li YZ, Niu GL, Lan MH, Jia QY and?Liang QL*. Near-Infrared Organic Dye-Based Nanoagent for the Photothermal Therapyof Cancer.?ACS Applied Materials & Interfaces?2016, 8, 29899-29905.
20. Li LL, Wang WX, Ding MY, Luo GA and?Liang QL*. Single-Cell-Arrayed Agarose Chip for in Situ Analysis of Cytotoxicityand Genotoxicity of DNA Cross-Linking Agents.?Analytical Chemistry?2016, 88, 6734-6742.
