人物成就
首次將PCNA方法應(yīng)用到浮游植物細胞周期和生長率現(xiàn)場觀測，開拓了浮游植物整體細胞免疫染色的方法。應(yīng)用浮游植物整體細胞免疫染色的方法發(fā)現(xiàn)了固氮藍藻（紅束毛藻）的固氮酶只分布在一部分（分化的）細胞內(nèi)，為了解此生物種如何克服固氮與光合之間矛盾提供了細胞化學(xué)的證據(jù)。應(yīng)用分子生物學(xué)和生理學(xué)方法首次發(fā)現(xiàn)在南極積雪里有細菌生存。
首次在浮游植物里克隆了線粒體細胞色素B基因，并應(yīng)用它設(shè)計分子探針用以探測噬魚費氏藻（Pfiesteria piscicida）, Karlodinium veneficum等甲藻。
首次在甲藻門內(nèi)發(fā)現(xiàn)mRNA編輯現(xiàn)象，推翻了過去認為Alveolata（包括纖毛蟲、瘧原蟲）可能不存在此現(xiàn)象的假說。同時為研究甲藻(如亞力山大藻)生產(chǎn)毒素和形成赤潮的遺傳機制提供了一條新思路。
克隆了甲藻特異的Rubisco（CO2固定酶）第三例，首次證明這個基因重復(fù)排列(tandem repeat)，并且這些重復(fù)基因組一起被轉(zhuǎn)錄、翻譯。用Rubisco基因首次發(fā)現(xiàn)浮游纖毛蟲攝食大型海藻，說明傳統(tǒng)的大型海藻的顆粒食物鏈需要修訂。
首次嘗試用線粒體細胞色素B基因分析浮游植物的系統(tǒng)進化，演示了這個基因作甲藻系統(tǒng)進化分析的潛力并顯示一些重要門類的系統(tǒng)地位需要修改。
首次發(fā)現(xiàn)甲藻spliced leader RNA trans-splicing, 為甲藻現(xiàn)場實時基因組表達模式的研究打下基礎(chǔ)。
在國際上首次系統(tǒng)完整地分析了甲藻基因組的結(jié)構(gòu)特性，描繪了珊瑚蟲和蟲黃藻共生過程中相互作用的分子機制，為今后甲藻基因組學(xué)和珊瑚-蟲黃藻共生生態(tài)系統(tǒng)的深入研究奠定了堅實的分子生物學(xué)基礎(chǔ)。這一研究成果不但填補了國內(nèi)空白，且處于國際領(lǐng)先水平。
代表作品
| Senjie Lin*, Shifeng Cheng, Bo Song, Xiao Zhong, Xin Lin, Wujiao Li, Ling Li, Yaqun Zhang, Huan Zhang, Zhiliang Ji, Meichun Cai, Yunyun Zhuang, Xinguo Shi, Lingxiao Lin, Lu Wang, Zhaobao Wang, Xin Liu, Sheng Yu, Peng Zeng, Han Hao, Quan Zou, Chengxuan Chen, Yanjun Li, Ying Wang, Chunyan Xu, Shanshan Meng, Xun Xu, Jun Wang, Huanming Yang, David A. Campbell, Nancy R. Sturm, Steve Dagenais-Bellefeuille, David Morse. (2015). The Symbiodinium kawagutii genome illuminates dinoflagellate gene expression and coral symbiosis. Science, 350(6261), 691-694. |
| Xinguo Shi, Xin Lin, Ling Li, Meizhen Li, Brain Palenik, Senjie Lin*. (2017). Transcriptomic and microRNAomic profiling reveals multi-faceted mechanisms to cope with phosphate stress in a dinoflagellate. The ISME journal, 11, 2209-2218. |
| Hao Luo, Xin Lin, Ling Li, Lingxiao Lin, Chao Zhang, Senjie Lin*. (2017). Transcriptomic and physiological analysis of the dinoflagellate Karenia mikimotoi reveal non-alkaline phosphatase-based molecular machinery of ATP utilization. Environmental Microbiology,19(11), 4506-4518. |
| Nanjing Ji, Lingxiao Lin, Ling Li, Liying Yu, Yaqun Zhang, Hao Luo, Meizhen Li, Xinguo Shi, Dazhi Wang, Senjie Lin*. (2018). Metatranscriptome analysis reveals environmental and diel regulation of a Heterosigma akashiwo (Raphidophyceae) bloom. Environmental Microbiology, 20(3), 1078-1094. |
| Liying Yu, Yaqun Zhang, Meizhen Li, Cong Wang, Xin Lin, Ling Li, Xinguo Shi, Chentao Guo, Senjie Lin*. (2019). Comparative metatranscriptomic profiling and microRNA sequencing to reveal active metabolic pathways associated with a dinoflagellate bloom. Science of the Total Environment, 134323. |
| Chichi Liu, Cheng, Shuk Han Cheng, Senjie Lin*. (2019). Illuminating the dark depths inside coral. Cellular Microbiology, 534842. |
| Senjie Lin*, Liying Yu, Huan Zhang. (2019). Transcriptomic Responses to Thermal Stress and Varied Phosphorus Conditions in Fugacium kawagutii. Microorganisms, 7(4), 96. |
| Xin Lin, Chentao Guo, Ling Li, Tangcheng Li, Senjie Lin*. (2019). Non-Conventional Metal Ion Cofactor Requirement of Dinoflagellate Alkaline Phosphatase and Translational Regulation by Phosphorus Limitation. Microorganisms, 7(8), 232. |
| deMendoza, A., Bonnet, A., Vargas-Landin,D.B., Ji,N., Hong,F.,Yang,F.,... Lin, S,& Ohta,H. (2018). Recurrent acquisition of cytosine methyltransferases into eukaryotic retrotransposons.Nature Communications,9(1), 1341 |
