1991年～1995年在哈爾濱工業(yè)大學(xué)應(yīng)用化學(xué)系讀本科，1995～1998年在華東理工大學(xué)化學(xué)系讀研究生，1998年～2001年在復(fù)旦大學(xué)物理系讀研究生并獲理論物理博士學(xué)位。2002年～2008年曾先后在美國貝勒醫(yī)學(xué)院生物化學(xué)系、克拉克大學(xué)化學(xué)系和美國洛斯阿拉莫斯國家實(shí)驗(yàn)室計(jì)算機(jī)與計(jì)算科學(xué)部從事博士后研究。2009～2016年在復(fù)旦大學(xué)生命科學(xué)學(xué)院生理與生物物理系任副研究員。2016年10月至今在南京工業(yè)大學(xué)生物與制藥工程學(xué)院任職。

生物控制論、計(jì)算結(jié)構(gòu)信息學(xué)導(dǎo)論、生物中的物理化學(xué)、生命科學(xué)與生物技術(shù)概論。

主要研究領(lǐng)域?yàn)橛?jì)算結(jié)構(gòu)生物學(xué)，包括分子動力學(xué)模擬、蛋白質(zhì)功能預(yù)測、蛋白質(zhì)折疊等。先后在PNAS、PRL、JMB、JCP、Plos One、Carbohydrate Research等國際一流權(quán)威期刊已經(jīng)發(fā)表了近30篇高質(zhì)量的學(xué)術(shù)論文；獲得了兩項(xiàng)國家自然科學(xué)基金面上項(xiàng)目資助。近年來，通過與酶工程實(shí)驗(yàn)組合作，從事工程酶的動力學(xué)改性設(shè)計(jì)、催化機(jī)制計(jì)算機(jī)模擬等方面的研究。

1、 Xiaokun Wu, Min Han, Dengming Ming*. Channel dynamics correlations through membrane dynamics: A multi-scale normal mode analysis. J. Chem. Phys. 143, 134113(2015)

2、Yian Yang, Jiaqiang Qian, Dengming Ming*. Molecular simulation of polysaccharide docking to proteins that have Tryptophan boxes in the binding pockets. Carbohydrate Research 414:78-84 (2015)

3、 Yunxiang Sun, Dengming Ming*. Energetic frustrations in protein folding at residue resolution: a homologous simulation study of Im9 proteins. Plos One. 9:e87719 (2014)

4、Xiongbo An, Xiaokun Wu and Dengming Ming*. Sequence-based functional sites prediction from a function annotated protein domain profile database. Journal of Fudan University, 52:768-778 (2013)

5、Dengming Ming, Michael E. Wall. Predicting binding sites by analyzing allosteric effects. Methods Molecular Biology. 796:423-36 (2012).

6、Mingyang Lu, Dengming Ming & Jianpeng Ma. fSUB: normal mode analysis with flexible substructures. J Phys. Chem. B, 116:8636-45(2012)

7、Xuehui Chen, Yunxiang Sun, Xiongbo An & Dengming Ming*. Virtual interface substructure synthesis method for normal mode analysis of superlarge molecular complexes at atomic resolution. J. Chem. Phys.135:144108 (2011)

8、Judith D. Cohn, Dengming Ming, Michael E. Wall. Prediction of functional sites in 50,000 protein domains using dynamics perturbation analysis. Biophysical Journal. 96:650a, 2009

9、Dengming Ming, Marian Anghel and Michael E. Wall. Hidden structure in protein energy landscape. Phys. Rev. E. 77:021902 (2008)

10、Dengming Ming, Judith Cohn and Michael E. Wall. Fast dynamics perturbation analysis for prediction of protein functional sites. BMC Struct Biol. 8:5 (2008)

11、Dengming Ming, Michael E. Wall and Kevin Y. Sanbonmatsu. Domain motions in Agonaute, the catalytic engine of RNA interference. BMC Bioinformatics 8:470 (2007)

12、Dengming Ming & Michael E. Wall. Interactions in native binding sites cause a large change in protein dynamics. J. Mol. Biol. 358: 213-23 (2006)

13、 Dengming Ming & Michael E. Wall. Allostery in a coarse-grained model of protein dynamics. Phys. Rev. Lett.95:198301. (2005)

14、Dengming Ming & Michael E. Wall. Quantifying allosteric effects in proteins. Proteins. 59: 697-707. (2005)

15、 Dengming Ming, Yifei Kong, Yinghao Wu & Jianpeng Ma. Simulation of d-actin filament of several microns. Biophys J. 85:27-35. (2003)

16、Dengming Ming, Yifei Kong, Yinghao Wu and Jianpeng Ma. Substructure Synthesis Methods for Simulating Large Molecular Complexes. Proc. Natl. Acad. Sci. U S A. 100:104-9. (2003).

17、Dengming Ming, Wen Tao, Jixian Dai, W. E. Evenson, Xianxi Dai. A unified solution of the specific-heat-phonon spectrum inversion problem. Europhys. Lett. 61:723-728. (2003)

18、 Dengming Ming, Yifei Kong, Maxime A. L., Zhong Huang and Jianpeng Ma. How to Describe Protein Movements without amino acids sequence and coordinates. Proc. Natl. Acad. Sci. U S A. 99:8620-5. (2002).

19、 Dengming Ming, Yifei Kong, Salih J. Wakil and Jiangpeng Ma. Domain Movements in Human Fatty Acid Synthase. Proc. Natl. Acad. Sci. U S A. 99:7895-9. (2002)

20、Dengming Ming, Wen Tao, Jixian Dai, W. E. Evenson, Xianxi Dai.Generalized emissivity inverse problem. Phys. Rev. E. 65: 045601.

21、 Dengming Ming, Wen Tao, Jixian Dai, W. E. Evenson, Xianxi Dai. Exact Solution of the Specific Heat-Phonon Spectrum Problem by Using the M?bius Inversion Formula. Phys. Rev. E. 62: R3019. (Rapid Communications 2000)