學(xué)習(xí)經(jīng)歷
聯(lián)合培養(yǎng)博士:新加坡國立大學(xué)2007.4-2008.4 專業(yè):生物醫(yī)學(xué)工程
博士:中山大學(xué)2004.9-2009.7 專業(yè):高分子化學(xué)與物理
學(xué)士:鄭州大學(xué)2000.9-2004.7 專業(yè):高分子材料與工程
工作經(jīng)歷
2012. 12- 2014. 12香港大學(xué)香江學(xué)者
2009.7-至今 暨南大學(xué) 副研究員
2008.5-2009.2 新加坡國立大學(xué) 研究員(Research Fellow)
研究方向
生物材料,組織工程及藥物載體
所授課程
承擔(dān)本科生及研究生《組織工程學(xué)》教學(xué)任務(wù)
社會職務(wù)
廣東省人體生物組織工程學(xué)會理事
榮譽(yù)獎勵
2014年度廣州市珠江科技新星
2013年廣東省“千百十人才工程”第六批校級培養(yǎng)對象
2012年度香江學(xué)者獎
2009年度廣東省南粵優(yōu)秀研究生
新加坡2007-2008年度優(yōu)秀公派留學(xué)生
主要著作
參編“生物醫(yī)用水凝膠”專著暨南大學(xué)出版社(2012)
主要論文
1 He LM*, Yuqiao Sun, Zuo QH, Wu WT, So KF, Xue W, Ramakrishna S Nano-engineered microenvironment for nerve regeneration Tissue Engineering Part A Revision submitted
2 He LM*, Tang S, Liao SS, Prabhakaran MP, Tian LL, Xue W, Ramakrishna S Surface modification of nanofibrous scaffolds with laminin multilayer via LbL assembly for enhancing neurite outgrowth Macromol. Biosci. 2013, DOI:10.1002/mabi.201300177
3 He LM*, Zuo QH, Shi YF, Xue W Microstructural Characteristics and Crystallization Behaviors of Poly(L-lactide) Scaffolds by Thermally Induced Phase Separation J. Appl. Polym. Sci. 2013, DOI: 10.1002/APP.39436
4 He LM, Zhao PP, Han Q, Wang XY, Cai X, Shi YF, Zhou LB, Zhang YM, Xue W Surface modification of poly-L-lactic acid fibrous scaffolds by a molecular-designed multi-walled carbon nanotube multilayer for enhancing cell interactions Carbon 2013, 56:224u2013 234
5 He LM, Shi YF, Han Q, Zuo QH, Ramakrishna S, Xue W, Zhou LB Surface modification of electrospun fibrous scaffold via polysaccharide-protein assembly multilayer for neuron growth J. Mater. Chem., 2012, 22 (26):13187-13196
6 Zuo QH, Zhong DG, Xie SS, Liu Q, Hong A, Huang YX, Shi YF, He LM*, Xue W Preparation and characterization of PEM-coated alginate microgels for controlled release of protein Biomedical Materials 2012, 7 (3):035012
7 Zhang YQ, He LM, Zeng CG, Zeng X, Quan DP, Zeng YS. Neurotrophin-3 Gene Modified Schwann Cells Promote TrkC Gene Modified Mesenchymal Stem Cells to Differentiate into Neuron-like Cells with Synaptogenesis in PLGA multiple-channel conduit in vitro. Cells Tissues Organs 2012, 195:313-322
8 He LM, Zuo QH, Xie SS, Huang YX, Xue W. Intelligent hydrogels for drug delivery system Recent Patents on Drug Delivery & Formulation 2011, 5:265-274.
9 Du BL, Xiong Y, Zeng CG, He LM, Zhang W, Quan DP, Wu JL, Li Y, Zeng YS Transplantation of artificial neural construct partly improved spinal tissue repair and functional recovery in rats with spinal cord transection Brain Research 2011, 1400: 87-98.
10 Ma K, Liao S, He LM, Lu J, Ramakrishna S, Chan CK Effects of Nanofiber/Stem Cell Composite on Wound Healing in Acute Full-Thickness Skin Wounds Tissue Engineering Part A 2011, 17:9-10
11 He LM, Liao SS, Quan DP, Ma K, Chan C, Ramakrishna S. Synergistic effects of electrospun PLLA fiber dimension and pattern on neonatal mouse cerebellum C17.2 stem cells. Acta Biomaterialia 2010, 6: 2960-2969
12 Zhang YQ, Zeng X, He LM, Ding Y, Li Y, Zeng YS. NT-3 modified Schwann cell promote TrkC gene modified mesenchymal stem cell to differentiate into neuron-like cells in vitro. Anatomical Science International 2010, 85:61-67.
13 He LM, Liao SS, Quan DP, Ngiam M, Chan C, Ramakrishna S, Lu J. The Influence of Laminin-Derived Peptides Conjugated to Lys-Capped-PLLA on Neonatal Mouse Cerebellum C17.2 Stem Cells. Biomaterials 2009, 30:1578-1586.
14 He LM, Zhang YQ, Zeng CG, Ngiam M, Liao SS, Quan DP, Zeng YS, Lu J, Ramakrishna S. Manufacture of PLGA multiple-channel conduits with precise hierarchical pore architectures and in vitro/vivo evaluation for spinal cord injury. Tissue Engineering Part C: Methods 2009,15:243-255.
15 He LM, Liu B, Guan XP, Xie GY, Liao SS, Quan DP, Cai DZ, Lu J, Ramakrishna S. Microstructure and properties of nano-fibrous PCL-b-PLLA scaffolds for cartilage tissue engineering. European Cells and Materials Journal 2009, 18:63-74.
16 He LM, Zhang YQ, Liao SS, Quan DP, Zeng YS, Lu J, Ramakrishna S. Fabrication and characterization of poly (L-lactic acid) nanofibrous scaffolds with 3D controlled architecture by thermally induced phase separation from a ternary polymer-solvent system. Polymer 2009, 50:4128-4138.
17 Xiong Y, Zeng YS, Zeng CG, Du BL, He LM, Quan DP, Zhang W, Wang JM, Wu JL, Li Y, Li J. Synaptic Transmission of Neural Stem Cells Grafted into 3-Dimentional PLGA Scaffold. Biomaterials 2009, 30:3711-3722.
18 Xu Q, Ding KL, He LM, Li JB, Guo YQ, Fan HJ. A new mechanism about the process of preparing nanoporous silica with activated carbon mold. MATERIALS SCIENCE AND ENGINEERING B-SOLID STATE MATERIALS FOR ADVANCED TECHNOLOGY 2005, 121:266-71.
承擔(dān)課題
1. 國家重點(diǎn)基礎(chǔ)研究發(fā)展計劃(973計劃)2014CB542205
周圍神經(jīng)損傷及修復(fù)后神經(jīng)再生與中樞神經(jīng)重塑的機(jī)制研究,作為主要成員參加子課題“周圍神經(jīng)損傷后中樞結(jié)構(gòu)重塑與功能修復(fù)”2014.1-2018.12100萬
2.國家自然基金青年科學(xué)基金項(xiàng)目51103062
納米支架中接觸引導(dǎo)與生物信號因子對神經(jīng)細(xì)胞軸突協(xié)同導(dǎo)向作用研究
2012.1-2014.1225萬
3.中國博士后科學(xué)基金第54批面上一等資助2013M540684
活性納米支架誘導(dǎo)脊髓軸突再生研究2014.1-2015.128萬
4.廣州市珠江科技新星專項(xiàng)
用于周圍神經(jīng)系統(tǒng)損傷修復(fù)的生物活性納米支架研究2014.1-2016.1230萬
5.廣東省自然科學(xué)基金博士啟動項(xiàng)目10451063201005499
靜電紡絲納米纖維中多重因子的負(fù)載及多級釋放的控制2010.10-2012.103萬
6.暨南大學(xué)引進(jìn)優(yōu)秀人才博士科研啟動基金
納米纖維中多重因子的負(fù)載及多級釋放研究2010.3-2013.24萬
7.暨南大學(xué)科研培育與創(chuàng)新基金海外合作者專項(xiàng)項(xiàng)目
活性納米支架:拓?fù)浣Y(jié)構(gòu)和梯度分布生物化學(xué)信號分子對神經(jīng)軸突協(xié)同導(dǎo)向作用研究10萬
8.新型聚合物材料設(shè)計合成與應(yīng)用廣東省高等學(xué)校重點(diǎn)實(shí)驗(yàn)室開放基金
納米支架中拓?fù)浣Y(jié)構(gòu)和梯度分布生物化學(xué)信號分子對神經(jīng)軸突協(xié)同導(dǎo)向作用研究1.5萬
所授課程:
承擔(dān)本科生及研究生《組織工程學(xué)》教學(xué)任務(wù)
社會職務(wù):
廣東省人體生物組織工程學(xué)會理事
榮譽(yù)與獎勵:
2014年度廣州市珠江科技新星
2013年廣東省“千百十人才工程”第六批校級培養(yǎng)對象
2012年度香江學(xué)者獎
2009年度廣東省南粵優(yōu)秀研究生
新加坡2007-2008年度優(yōu)秀公派留學(xué)生.