研究領(lǐng)域與興趣發(fā)展環(huán)境友好的綠色合成化學(xué)，研發(fā)高效率和高選擇性的不對(duì)稱催化反應(yīng)方法學(xué)。與此同時(shí)，合成、設(shè)計(jì)生物活性分子，研究其生物活性。

教育背景與學(xué)術(shù)經(jīng)歷

個(gè)人經(jīng)歷 ：

2007年2月—2009年9月美國(guó)普林斯頓大學(xué)博士后 LOL

2005年8月—2006年10月德國(guó)海德堡大學(xué)洪堡客座研究員

2005年2月—2005年8月瑞典斯德哥爾摩大學(xué)博士后

2004年8月—2005年2月中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所研究助理

1999年8月—2004年7月中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所博士

1995年9月—1999年7月西北大學(xué)化學(xué)系

學(xué)術(shù)兼職與社會(huì)服務(wù)

教學(xué)情況

1. 基礎(chǔ)有機(jī)化學(xué)實(shí)驗(yàn)本科生實(shí)驗(yàn)課.

2. 高等有機(jī)化學(xué)碩士研究生學(xué)位課.

承擔(dān)項(xiàng)目與課題

國(guó)家自然科學(xué)基金青年基金項(xiàng)目

國(guó)家自然科學(xué)基金面上項(xiàng)目（2014/1/1-2017/12/31）

代表性論文及著作

課題組成立以來發(fā)表文章（2010年9月）

7. Metal-Free Intramolecular Carbocyanation of Activated Alkenes: Functionalized Nitriles Bearing β-Quaternary Carbon Centers

Jian-Ming Chen, Gong-Feng Zou, Wei-Wei Liao*,?Angew. Chem. Int. Ed.?2013,?52, 9296.

(This paper has been chosen as a "Hot Paper" by the Editors for its importance in a rapidly evolving field of high current interest.)

6. Asymmetric organocatalytic allylic alkylation of Reissert compounds: a facile access to chiral 1,1-disubstituted 1,2-dihydroisoquinolines

Tian-You Qin, Wei-Wei Liao*, Yan-Jing Zhang and Sean Xiao-An Zhang*,?Org. Biomol. Chem.,2012, DOI: 10.1039/c2ob27269e.

5. Controllable Regioselective Construction of Both Functional α-Methylene-β- and -γ-amino Acid Derivatives Through an Organocatalyzed Tandem Allylic Alkylation and Amination

Feng?Pan, Jian-Ming Chen, Tian-You Qin, Sean Xiao-An Zhang, and Wei-Wei Liao*, Eur. J. Org. Chem,?2012, 5324.

4. Lewis Base Promoted Intramolecular Acylcyanation of α-Substituted Activated Alkenes: Construction of Ketones Bearing β-Quaternary Carbon Centers

Zhe Zhuang, Jian-Ming Chen, Feng Pan, and Wei-Wei Liao*, Org. Lett,2012, 14, 2354.

3. A Novel Multicomponent Tandem Phosphine-Catalyzed Umpolung Reaction: Facile

Access to Highly Functionalized α-Aminonitriles

Jian-Ming Chen, Yin-Zhi Fang, Zhong-lin Wei, Wei-Wei Liao*,?Synthesis, 2012, 44, 1849. (An invited contribution to the special issue on tandem reaction)

2.Construction of Highly Functional α-Amino Nitrilesviaa Novel Multicomponent Tandem Organocatalytic Reaction: a Facile Access to α-Methylene γ-Lactams

Feng Pan, Jian-Ming Chen, Zhe Zhuang,Yin-Zhi Fang,Sean Xiao-An Zhang and Wei-Wei Liao.?Org. Biomol. Chem.2012,?10, 2214.

1. Construction of Highly Functional Quaternary Carbon Stereocenters?viaan Organocatalytic Tandem Cyanation_Allylic Alkylation Reaction

Zhe Zhuang, Feng Pan, Jian-Guo Fu, Jian-Ming Chen, and Wei-Wei Liao*.?Org. Lett.2011, 13, 6164.

2009年以前發(fā)表文章：

1. Controllable Diastereoselective Cyclopropanation. Enantioselective Synthesis of Vinylcyclopropanes via Chiral Telluronium Ylides

Wei-Wei, Liao, Kai Li, and Yong Tang.?J. Am. Chem. Soc.2003, 125, 13030.

2. A facile Reaction of Imines with Telluronium Allylide. Highly stereoselective Synthesis of Vinylaziridines

Wei-Wei, Liao, Xian-Ming Deng, Yong Tang.?Chem. Commun.2004, 1516.

3. Telluronium Salts Mediated Aziridination of Chiral N-tert Butylsulfinylimines: Highly Stereoselective Synthesis of Optically Active Vinylaziridines

Jun-Cheng Zheng, Wei-Wei, Liao, Xiao-Xia Sun, Xiu-Li Sun, Yong Tang, Li-Xin Dai, and Jin-Geng Deng,?Org. Lett.2005, 7,?5789.

4. The Michael Addition-Elimination of Ylides to -Unsaturated Imines. Highly Stereoselective Synthesis of Vinylcyclopropanecarbaldehydes and Vinylcyclopropylaziridines

Jun-Cheng Zheng, Wei-Wei Liao, Yong Tang, Xiu-Li Sun, and Li-Xin Dai,?J. Am. Chem. Soc.2005, 127, 12222.

5. Acyclic Amino Acid-catalyzed Direct Asymmetric Aldol Reactions: Alanine, the Simplest Stereoselective Organocatalyst

Armando Cordova, Weibiao Zou, Ismail Ibrahem, Efraim Reyes, Magnus Engqvist and Wei-Wei Liao,Chem. Commun.2005, 3586.

6. A Concise Enantioselective Synthesis of Iminosugar Derivatives

Wei-Wei Liao, Ismail Ibrahem and Armando Córdova,?Chem. Commun.,2006, 674.

7. Direct One-pot Highly Enantioselective Assembly of Polyketide and Carbohydrate Synthons

Gui-Ling, Zhao, Wei-Wei Liao, Armando Córdova,?Tetrahedron Lett.2006, 47, 4929.

8. Enantioselective Synthesis of Vinylcyclopropanes and Vinylepoxides Mediated by Camphor- Derived Sulfur Ylides: Rationale of Enantioselectivity, Scope, and Limitation

Xian-Ming Deng, Ping Cai, Song Ye, Xiu-Li Sun, Wei-Wei Liao, Kai Li, Yong Tang, Yun-Dong Wu, and Li-Xin Dai.?J. Am. Chem. Soc.2006, 128, 9730.

9. Sequential Couplingu2013Isomerizationu2013Coupling Reactions u2013 A Novel Three-Component Synthesis of Aryl Chalcones

Wei-Wei Liao, T. J. J. Mueller,?Synlett?2006, 20, 3469.

10. Dichotomies in Microwave-Assisted Propargyl-Isomerizationu2013Claisen Domino Sequences Dependent on Base Strengths

Daniel M. Du2019Souza, Wei-Wei Liao, Frank Rominger T. J. J. Mueller.?Org. Biomol. Chem.2008, 6, 532u2013539

11. Analysis and purification of alcohol-sensitive chiral compounds using 2, 2, 2 -trifluoroethanol as a modifier in supercritical fluid chromatography

Neal Byrne, Eleanor Hayes-Larson, Wei-Wei Liao, Christina M. Kramla.?J. Chromatogr. B,?2008, 875, 237.