人物經(jīng)歷
學(xué)習(xí)經(jīng)歷
1998.9~2002.6,山東農(nóng)業(yè)大學(xué)食品科學(xué)與工程專業(yè),本科
2004.9~2006.6,暨南大學(xué)微生物與生化藥學(xué)專業(yè),碩士
2006.9~2009.12,中國農(nóng)業(yè)大學(xué)食品科學(xué)專業(yè),博士
工作經(jīng)歷
2002.9-2010.3,山東農(nóng)業(yè)工程學(xué)院,講師
2010.3至今,暨南大學(xué)理工學(xué)院食品科學(xué)與工程系,研究員/博導(dǎo)
2012.11月至今,暨南大學(xué)理工學(xué)院副院長/食品安全與營養(yǎng)研究院常務(wù)副院長/食品科學(xué)與工程系主任/科技處副處長
研究方向
(1)植物化學(xué)物花色苷等對慢性疾病營養(yǎng)干預(yù):采用藍(lán)莓、草莓等果蔬中花色苷,國際上率先開展了對生殖損傷的營養(yǎng)干預(yù),建立了對生殖功能評價的體系和平臺;同時對皮膚光老化、脂質(zhì)代謝和肝損傷等營養(yǎng)干預(yù)也開展了系列研究;利用平臺體系篩選藥食同源功能活性因子,配伍并研發(fā)男性和女性備孕產(chǎn)品、護(hù)膚產(chǎn)品、減肥及護(hù)肝產(chǎn)品等。
(2)研究花色苷單體制備、產(chǎn)品開發(fā)及色澤控制:(a)快速、高效的果蔬花色苷單體等生物活性物質(zhì)的提取、分離、鑒定與純化技術(shù)體系;(b)富含花色苷產(chǎn)品的果酒和果醋功能產(chǎn)品的開發(fā);(c)富含花色苷產(chǎn)品加工和貯藏過程中色澤的變化及護(hù)色技術(shù)研究。
(3)研究花色苷穩(wěn)態(tài)化體系:針對花色苷抗氧化能力強,但穩(wěn)定性差、吸收率低等缺點,采用殼聚糖、環(huán)糊精等構(gòu)建穩(wěn)態(tài)化的納米/微米包埋體系,并研究精準(zhǔn)靶向釋放,開發(fā)花色苷功能配料。
(4)研究食品分子溯源和快檢技術(shù):針對食品特別是高附加值食品摻假亂像,建立了食品種屬鑒定和地理標(biāo)識檢測技術(shù)。開展了核酸適配體對重金屬、毒素、微生物等的篩選及快檢技術(shù)和產(chǎn)品的研究開發(fā)。
學(xué)術(shù)成果
主要論文
[1] Li XS, Guo JT, Jiang XW, Sun, JX, Tian LM, Jiao R, Tang YG,Bai WB*. Cyanidin-3-O-glucoside protects against cadmium-induced dysfunction of sex hormone secretion via the regulation of hypothalamus-pituitary-gonadal axis in male pubertal mice. Food and Chemical Toxicology, 2019, DOI:10.1016/j.fct.2019.04.033 (IF=3.977,2區(qū)Top)
[2] Li Y, Ran GJ, Lu G, Ni XY, Liu DL, Sun JX, Xie CF, Yao DS*,Bai WB*. Highly Sensitive Label-Free Electrochemical Aptasensor Based on Screen-Printed Electrode for Detection of Cadmium (II) Ions. Journal of the Electrochemical Society, 2019, 166(6): B449-B455 (IF=3.622, 2區(qū)Top)
[3] Jiang XW, Cao CT, Sun WW, Chen ZS, Li XS, Nahar, L, Sarker, SD, Georgiev, MI,Bai WB*. Scandenolone from Cudrania tricuspidata fruit extract suppresses the viability of breast cancer cells (MCF-7) in vitro and in vivo. Food and Chemical Toxicology, 2019, 126: 56-66 (IF=3.977,2區(qū)Top)
[4] Sun JX, Luo HX, Li XH, Li XS, Lu YY,Bai WB*. Effects of low power ultrasonic treatment on the transformation of cyanidin-3-O-glucoside to methylpyranocyanidin-3-O-glucoside and its stability evaluation. Food Chemistry, 2019, 276: 240-246 (IF=4.946,2區(qū)Top)
[5] Tian LM, Tan YS, Chen GW, Wang G, Sun JX, Ou SY, Chen W,Bai WB*. Metabolism of anthocyanins and consequent effects on the gut microbiota. Critical Reviews in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1533517(IF=6.202,1區(qū))
[6] Li XS, Yao ZL, Jiang XW, Sun JX, Ran GJ, Yang X, Zhao YQ, Yan Y, Chen ZS, Tian LM,Bai WB*. Bioactive compounds from Cudrania tricuspidata: A natural anticancer source. Critical Reviews in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1541866 (IF=6.202,1區(qū))
[7] Jiang XW, Zhu CJ, Li XS, Sun JX, Tian LM,Bai WB*. Cyanidin-3-O-glucoside at Low Doses Protected against 3-Chloro-1,2-propanediol Induced Testis Injury and Improved Spermatogenesis in Male Rats. Journal of Agricultural and Food Chemistry, 2018, 66(48): 12675-12684 (IF=3.412, 1區(qū))
[8] Jiang XW, Li XS, Zhu CJ, Sun JX, Tian LM, Chen W,Bai WB*. The target cells of anthocyanins in metabolic syndrome. Critical Review in Food Science and Nutrition, 2018, DOI:10.1080/10408398.2018.1491022 (IF=6.077, 1區(qū))
[9] Yang DC, Jiang XW, Sun JX, Li X, Li XS, Jiao R, Peng ZY, Li YQ,Bai WB*. Toxic effects of zearalenone on gametogenesis and embryonic development: A molecular point of review. Food and Chemical Toxicology, 2018, 119: 24-30 (IF=3.977,二區(qū)Top)
[10] Liu ZH, Hu YF, Li X, Mei ZX, Wu S, He Y, Jiang, XW, Sun JX, Xiao, JB, Deng, LH*,Bai WB*. Nanoencapsulation of Cyanidin-3- O-glucoside Enhances Protection Against UVB-Induced Epidermal Damage through Regulation of p53-Mediated Apoptosis in Mice. Journal of agricultural and food chemistry, 2018, 66(21): 5359-5367(IF=3.412, 1區(qū))
[11] Sun JX, Li MW, Zou FY, Bai S, Jiang XW, Tian LM, Ou SY, Jiao R*,Bai WB*. Protection of cyanidin-3-O-glucoside against acrylamide- and glycidamide-induced reproductive toxicity in leydig cells. Food and Chemical Toxicology, 2018, 119: 268-274 (IF=3.977,二區(qū)Top)
[12] Li X, Guo JT, Liang N, Jiang XW, Song Y, Ou SY, Hu YF, Jiao R*,Bai WB*. 6-Gingerol Regulates Hepatic Cholesterol Metabolism by Up-regulation of LDLR and Cholesterol Efflux-Related Genes in HepG2 Cells. Frontiers in Pharmacology,
[13] Li XS, Jiang XW, Sun JX, Zhu CJ,Bai WB*. Recent advances of medical foods in China: The opportunities and challenges under standardization. Food and chemical toxicology, Food and Chemical Toxicology, 2018, 119: 342-354 (IF=3.977,二區(qū)Top)
[14] Wen LN, Jiang XW, Sun JX, Li X, Li XS, Tian LM, Li Y,Bai WB*. Cyanidin-3-O-glucoside promotes the biosynthesis of progesterone through the protection of mitochondrial function in Pb-exposed rat leydig cells. Food and Chemical Toxicology, 2018, 112: 427-434 (IF=3.977,二區(qū)Top)
[15] Li X, Jiang XW, Sun JX, Zhu CJ, Li XL, Tian LM, Liu L,Bai WB*. Cytoprotective effects of dietary flavonoids against cadmium-induced toxicity: Mechanisms of dietary flavonoids against cadmium.Annals of the New York Academy of Sciences, 2017 , 1398 (1) :5-19 (IF=4.706)
[16] Hu YF, Li ZH, Wang LF, Deng LH, Sun JX,Jiang XW, Zhang Y, Wang YF,Bai WB*. Scandenolone, a natural isoflavone derivative from Cudrania tricuspidata fruit, targets EGFR to induce apoptosis and block autophagy flux in human melanoma cells. Journal of Functional Foods, 2017 ,
[17] He Y, Hu YF, Jiang XW, Chen TF, Ma YT, Wu S, Sun JX, Jiao R, Li X, Deng LH*,Bai WB*. Cyanidin-3-O-glucoside inhibits the UVB-induced ROS/COX-2 pathway in HaCaT cells. Journal of Photochemistry and Photobiology. B, Biology, 2017, 177: 24-31.(IF=2.673,3區(qū))
[18] Sun JX, Xu W, Zhu CJ, Hu YF, Jiang XW, Su ZJ, Huang YD, Jiao R *,Bai WB*. Cyanidin-3-O-Glucoside Protects against 1,3-Dichloro-2-Propanol-Induced Reduction of Progesterone by Up-regulation of Steroidogenic Enzymes and cAMP Level in Leydig Cells. Frontiers in Pharmacology. 2016, 7;
[19] Hu YF,Ma YT,Wu S,Chen TF,He Y,Sun JX,Jiang XW,Huang YD,Deng LH *,Bai WB*. Protective effect of cyanidin-3-O-glucoside against ultraviolet B radiation-induced cell damage in human HaCaT keratinocytes. Frontiers in Pharmacology.2016; doi: 10.3389/fphar.2016.00301 (IF=4.400,2區(qū))
[20] Li MW, Sun JX, Zou FY, Bai S, Jiang XW, Jiao Rui, Ou SY, Zhang H, Su ZJ, Huang YD,Bai WB*. Glycidamide inhibits progesterone production through reactive oxygen species-induced apoptosis in R2C Rat Leydig Cells. Food and Chemical Toxicology. 2016 (IF=3.977,二區(qū)Top)
[21] Sun JX, Mei ZX, Tang YJ, Ding LJ, Jiang GC, Zhang C, Sun AD*,Bai WB*. Stability, antioxidant capacity and degradation kinetics of pelargonidin-3-glucoside exposed to power ultrasound at low temperature.Molecules, 2016, 21(9), 1109; doi:10.3390/molecules21091109 (IF=3.098,Q2)
[22] Sun JX, Li XH, Lin XY, Mei ZX, Li YT, Ding LJ*,Bai WB*. Sonodegradation of Cyanidin-3-glucosylrutinoside: degradation kinetic analysis and its impact on antioxidant capacity in vitro.Journal of the Science of Food and Agriculture, 2016 (IF=2.463,2區(qū))
[23] Zhang ZH, Zou YY, Wu TG, Huang CH, Pei KH, Zhang GW, Lin XH,Bai WB*, Ou SY*. Chlorogenic acid increased 5-hydroxymethylfurfural formation when heating fructose alone or with aspartic acid at two pH levels.Food Chemistry, 2016, 190: 832u2013835(IF=4.946,2區(qū)top)
[24] Song Y, Wen LN, Sun JX,Bai WB*, Jiao R, Hu YF, Peng XC, He Yong, Ou SY*. Cytoprotective mechanism of ferulic acid against high glucose-induced oxidative stress in cardiomyocytes and hepatocytes.Food & Nutriton Research, 2016, 60, 30323. (IF=2.039,2區(qū))
[25] Sun JX, Bai S,Bai WB*, Zou FY, Zhang L, Li GQ, Hu YF, Li MW, Yan RA, Su ZJ*, Huang YD. 1,3-Dichloro-2-propanol inhibits progesterone production through the expression of steroidogenic enzymes and cAMP concentration in Leydig cells. Food Chemistry, 2014, 154:330u2013336 (IF=3.334,2區(qū)top)
[26] Sun JX, Bai S,Bai WB*, Zou FY, Zhang L, Su ZJ, Zhang QH, Ou SY, Huang YD *, Toxic Mechanisms of 3-Monochloropropane-1,2-Diol on Progesterone Production in R2C Rat Leydig Cells. Journal of Agricultural and Food Chemistry, 2013, 61: 9955-9960 (IF=2.906, 1區(qū)top)
[27]Bai WB, Xu WT, Huang KL, Yuan YF, Cao SS, Luo YB. A novel common primer multiplex PCR (CP-M-PCR) method for the simultaneous detection of meat species. Food Control, 2009, 20: 366-370 (IF=2.842,2區(qū))
主要著作
[1]車會蓮、馬良、白衛(wèi)濱、邵美麗、李昌模等,食品安全性評價綜合實驗:中國林業(yè)出版社,2014(參編)
[2]賈敬敦,蔣丹平,陳昆松,葛毅強,白衛(wèi)濱等,食品產(chǎn)業(yè)科技創(chuàng)新發(fā)展戰(zhàn)略,化學(xué)工業(yè)出版社,95.6萬字,2013(參編)
[3]賈敬敦,孫曉明,陳昆松,葛毅強,白衛(wèi)濱等,農(nóng)業(yè)前沿技術(shù)與戰(zhàn)略新興產(chǎn)業(yè),中國農(nóng)業(yè)出版社, 120萬字,2011(參編)
[4]張燕,張輝,孫建霞,白衛(wèi)濱等,果品的商品化處理與配送,中國勞動社會保障出版社,12.5萬字,2012(副主編)
[5]轉(zhuǎn)基因食品安全與檢測技術(shù).北京:科學(xué)出版社,2009,參編
承擔(dān)課題
[1]國家自然科學(xué)基金(面上):超聲催陳促進(jìn)紅葡萄酒花色苷衍生物的生成機制,2018-2021,60萬;
[2]國家重點研發(fā)計劃:主要食品全產(chǎn)業(yè)鏈品質(zhì)質(zhì)量控制關(guān)鍵技術(shù)開發(fā)研究課題任務(wù)、2016-2020,經(jīng)費107萬元;
[3]廣州市產(chǎn)學(xué)研協(xié)同創(chuàng)新重大專項:嶺南特色富含花色苷的果酒、果醋超聲催陳關(guān)鍵技術(shù)及產(chǎn)品功能評價研究、2017-2020,經(jīng)費100萬元;
[4]國家自然科學(xué)基金(面上):草莓天竺葵素-3-葡萄糖苷對食品中氯丙醇導(dǎo)致細(xì)胞氧化應(yīng)激的營養(yǎng)干預(yù)機制,2015-2018,經(jīng)費82萬元;
[5]國家科技支撐計劃課題:食品中熱反應(yīng)伴生危害物毒理學(xué)檢測及風(fēng)險評估關(guān)鍵技術(shù)研究,2012-2014,經(jīng)費145萬元;
[6]國家自然科學(xué)基金(青年):楊梅花色苷抑制重金屬損傷睪丸間質(zhì)細(xì)胞的機制研究, 2012-2015,27萬元;
[7]國家863計劃項目:優(yōu)良益生菌高效篩選與應(yīng)用關(guān)鍵技術(shù)子課題,2011-2015,50萬元;
發(fā)明專利
[1]一種利用多重PCR技術(shù)檢測轉(zhuǎn)基因番木瓜的方法.國家發(fā)明專利,2017,第一完成人(授權(quán)并轉(zhuǎn)讓)
[2]大蒜果聚糖合成酶在生產(chǎn)高果聚糖中的應(yīng)用.國家發(fā)明專利,2014,第二完成人(授權(quán))
[3]一種無苦味柑肉果酒的無渣排放生產(chǎn)方法.國家發(fā)明專利,2014,第二完成人(授權(quán))
[4]矢車菊素u20113u2011Ou2011葡萄糖苷在制備3u2011氯u20111,2u2011丙二醇引發(fā)的疾病藥物中的應(yīng)用.國家發(fā)明專利,2018,第一完成人(授權(quán))
[5]矢車菊素-3-O-葡萄糖苷對1,3-二氯-2-丙醇的生殖毒性的干預(yù)作用.國家發(fā)明專利,2015,第一完成人(公開)
[6]矢車菊素-3-葡萄糖苷對UVB誘導(dǎo)HaCaT細(xì)胞損傷的防護(hù)作用.國家發(fā)明專利,2015,第一完成人(公開)
[7]矢車菊素-3-O-葡萄糖苷對丙烯酰胺和環(huán)氧丙酰胺的生殖毒性的干預(yù)作用.國家發(fā)明專利,2018,第二完成人(公開)
[8]一種穩(wěn)定包埋花色苷的改性環(huán)糊精/羧甲基殼聚糖納米顆粒的制備方法.國家發(fā)明專利,2017,第一完成人(公開)
[9] Scandinone在制備預(yù)防及治療惡性黑色素瘤藥物中的應(yīng)用.國家發(fā)明專利,2017,第一完成人(公開)
[10]攀登魚藤異黃酮在制備預(yù)防和/或治療宮頸癌藥物中的應(yīng)用.國家發(fā)明專利,2017,第一完成人(公開)
[11]鎘離子核酸適配體及絲網(wǎng)印刷電極電化學(xué)生物傳感器.國家發(fā)明專利,2018,第一完成人(公開)
講授課程
《轉(zhuǎn)基因食品安全性評價》,本科生
《食品營養(yǎng)學(xué)》,本科生
《高級食品安全研究進(jìn)展》,研究生
榮譽獎勵
國家級青年人才
社會職務(wù)
擔(dān)任廣東省食品安全分子快速檢測工程技術(shù)中心主任、廣東省食品學(xué)會青年工作委員會主任、中國食品科學(xué)技術(shù)學(xué)會第三屆青年工作委員會委員,擔(dān)任食品領(lǐng)域Top期刊Critical Reviews in Food Science and Nutrition和Food and Chemical Toxicology雜志的客座主編等。