朱鋼國，男，1978年10月生，浙江省金華市金東區(qū)人，現(xiàn)為浙江師范大學化學與生命科學學院教授、碩士生導師

1996.9-2000.7浙江師范大學化學系獲理學學士，化學專業(yè)

2000.9-2005.7 中科院上海有機化學研究所獲理學博士，有機化學專業(yè)

2005.9-2007.10美國普渡大學諾貝爾獎得主Negishi小組博士后研究

2007.11-2008.10 美國印第安納大學化學系博士后研究

2008.12-至今 浙江師范大學化學與生命科學學院任教，教授（2011.12）

浙江省“151”人才第三層次培養(yǎng)對象（2009.6）

浙江省高校中青年學科帶頭人(2013.6)

主要從事金屬有機化學專業(yè)領域的研究，發(fā)表Chem. Commun.、Org. Lett.、Chem. Eur. J.、Adv. Synth. Catal.、J. Org. Chem.等SCI論文30多篇，著作章節(jié)1篇，其中以通訊作者或第一作者發(fā)表影響因子大于4論文19篇。

1. Pd-catalyzed addition of boronic acids to ynol ethers: a highly regio- and stereoselective synthesis of trisubstituted vinyl ethers. Bai, Y.; Yin, J.; Kong, W.; Mao, M.; Zhu, G.* Chem. Commun.

2. A Regio- and Stereoselective Entry to ,-Disubstituted Vinyl Ethers via the Sequential Hydroboration/Suzukiu2013Miyaura Coupling of Ynol Ethers. Cui, W.; Mao, M.; He, Z.; Zhu, G.* J. Org. Chem.

3. Palladium-Catalyzed Direct Alkenylation of 2-Oxazolones: An Entry to 3,4,5-Trisubstituted 2-Oxazolones, Lu, Z.; Luo, F.; Wang, L.; Zhu, G.* J. Org. Chem.

4. Highly stereoselective synthesis of (Z)-1,2-dihaloalkenes by a Pd-catalyzed hydrohalogenation of alkynyl halides. Zhu, G.*; Chen, D.; Wang, Y.; Zheng, R. Chem. Commun.

5. Preparation of 3,4,5-Trisubstituted Oxazolones by Pd-Catalyzed Coupling of N-Alkynyl tert-Butyloxycarbamates with Aryl Halides and Related Electrophiles. Lu, Z.; Cui, W.; Xia, S.; Bai, Y.; Luo, F.; Zhu, G.* J. Org. Chem.

6. Palladium-catalyzed haloallylation of aromatic ynol ethers with allyl chlorides: a highly regio- and stereoselective approach to (1E)--chloroenol ethers. Cai, H.; Yuan, Z.; Zhu, W.; Zhu, G.* Chem. Commun.

7. Palladium-catalyzed highly regio- and stereoselective synthesis of (1E)- or (1Z)-1,2-dihalo-1,4-dienes via haloallylation of alkynyl halides. Chen, X.; Kong, W.; Cai, H.; Kong, L.; Zhu, G.* Chem. Commun.

8. Palladium-Catalyzed Dienylation of Haloalkynes Using 2,3-Butadienyl Acetates: A Facile Access to (1Z)-1,2-Dihalo-3-vinyl-1,3-dienes. Chen, D.; Chen, X.; Lu, Z.; Cai, H.; Shen, J.; Zhu, G.* Adv. Synth. Catal

9. Synthesis of Multisubstituted Enamides via Pd-Catalyzed Chloroallylation of Ynamides. Lu, Z.; Kong, W.; Yuan, Z.; Zhao, X.; Zhu. G.* J. Org. Chem

10. Palladium-Catalyzed Coupling of Haloalkynes with Allyl Acetate: A Highly Regio- and Stereoselective Synthesis of (Z)--Haloenol Acetates. Chen, X.; Chen, D.; Lu, Z.; Kong, L.; Zhu, G.* J. Org. Chem

11.Palladium-Catalyzed Hydroarylation, Hydroalkenylation, and Hydrobenzylation of Ynol Ethers with Organohalides: A Regio- and Stereoselective Entry toα,β- andβ,β-Disubstituted Alkenyl Ethers, Cui, W.; Ying, J.;Zheng, R.; Cheng, C.; Bai, Y.Zhu, G.*J. Org. Chem.2014,79, 3487-3493.

12.An unprecedented Pd-catalyzedtrans-addition of boronic acids to ynamides. Yang, Y.; Wang, L.; Zhang, J.; Jin, Y.;Zhu, G.*Chem. Commun.2014,50, 2347-2349.

13.Synthesis ofcis-1,2-dichlorovinylsulfones via Fe-catalyzed regio- and stereoselective addition of sulfonyl chlorides to aromatic chloroalkynes. Wang, L.; Zhu, H.; Che, J.; Yang, Y.*;Zhu, G.*Tetrahedron Lett.2014,55,1011-1013.

14.Synthesis of (Z)-1-Thio- and (Z)-2-Thio-1-alkenyl Boronates via Copper-Catalyzed Regiodivergent Hydroboration of Thioacetylenes: An Experimental and Theoretical Study.Zhu, G.*; Kong, W.; Feng, H.; Qian, Z.*J. Org. Chem.2014,79, 1786-1795.

15.A regio- and stereoselective entry to (Z)-β-halo alkenyl sulfides and their applications to the access of stereodefined trisubstituted alkenes. Liu, G.; Kong, L.; Shen, J.;Zhu, G.*Org. Biomol. Chem.2014,12, 2310-2321.

2013年

16.Palladium-Catalyzed Direct Alkenylation of 2-Oxazolones: An Entry to 3,4,5-Trisubstituted 2-Oxazolones, Lu, Z.; Luo, F.; Wang, L.;Zhu, G.*J. Org. Chem.2013,78, 10894-10901.

17.Pd-catalyzed addition of boronic acids to ynol ethers: a highly regio- and stereoselective synthesis of trisubstituted vinyl ethers. Bai, Y.; Yin, J.; Kong, W.; Mao, M.;Zhu, G.*Chem. Commun.2013,49,7650-7652.

18.Regioselective and Stereoselective Entry to β,β-Disubstituted Vinyl Ethers via the Sequential Hydroboration/Suzukiu2013Miyaura Coupling of Ynol Ethers. Cui, W.; Mao, M.; He, Z.;Zhu, G.*J. Org. Chem.2013,78, 9815-9821.

19.Copper-catalyzed direct thiolation of xanthines and related heterocycles with disulfides. He, Z.; Luo, F.;*Li, Y.;Zhu, G.*Tetrahedron Lett.2013,54, 5907-5910.

20.An operationally simple approach to (E)-α-halo vinyl sulfides and their applications for accessing stereodefined trisubstituted alkenes.Yang, Z.(本科生); Chen, X.; Kong, W.; Xia, S.; Zheng, R.; Luo, F.;Zhu, G.*Org. Biomol. Chem.2013,11, 2175-2185.

2012年

21.Highly stereoselective synthesis of (Z)-1,2-dihaloalkenesby a Pd-catalyzed hydrohalogenation of alkynyl halides.Zhu, G.*;Chen, D.; Wang, Y.; Zheng, R.Chem. Commun.2012,48,5796-5798.

22.Preparation of 3,4,5-Trisubstituted Oxazolones by Pd-Catalyzed Coupling ofN-Alkynyltert-Butyloxycarbamates with Aryl Halides and Related Electrophiles. Lu, Z.; Cui, W.; Xia, S.; Bai, Y.; Luo, F.;Zhu, G.*J. Org. Chem.2012,77,9871-9877.

23.A Facile Access to 3,5-Disubstituted Oxazolones Featuring a Cu-catalyzed Cyclization ofN-Alkynyltert-Butyl Carbamates. Lu, Z.; Yang, Z.; Cui, W.;Zhu, G.*Chem. Lett.2012,41, 636-638.

24.Approach to highly functionalized oxazolones by a Pd-catalyzed cyclization ofN-alkynyltert-butyloxycarbamates. Lu, Z.; Xu, X.; Yang, Z.; Kong, L.*;Zhu, G.*Tetrahedron Lett.2012,53,3433-3436.

25.A Facile Method for the Synthesis of 3-Alkyloxindole. Du, T.;Zhu, G.*; Zhou, J.*Lett. Org. Chem.2012,9, 225-232.

1.2012－2015,國家自然科學基金面上項目－“基于1,2-雙官能團化烯烴的偶聯(lián)反應選擇性合成多取代烯烴”；

2.2012－2014,浙江省杰出青年基金-“1-鹵-1-硫代烯烴的立體選擇性合成及其三取代烯烴的構建”；

3.2010－2012,國家自然科學基金青年項目-“偶極烯丙基鈀的環(huán)加成反應研究”，已結題；

4.2010－2012,浙江省錢江人才計劃項目-“抗禽流感藥物達菲的合成工藝研究”，已結題。

“雜原子取代炔烴的親核鈀化反應方法學研究”獲2012年浙江省高等學�？蒲谐晒�獎一等獎。

為本科生主講課程有《有機化學》、《有機化學實驗》、《有機合成化學》，指導本科生論文10余篇；為研究生開設《金屬有機化學》等課程，指導培養(yǎng)碩士研究生4名，獲校優(yōu)秀碩士論文2篇。

1、順式-1-鹵-2-氯代烯烴及其制備方法和應用，朱鋼國、陳東旭，專利號：ZL 201210004757.9。

2、一種莽草酸的合成方法，朱鋼國、崔偉劍、夏思苑、何祖鶯，專利號：ZL 201210094437.7。

3、一種3,4,5-三取代噁唑-2-酮的合成方法，朱鋼國、盧增輝、劉鴿、羅芳、夏思苑，專利號：ZL 201210283568.X。

4、一種利用順式-1-鹵-2-氯代烯烴合成維生素A的方法，朱鋼國，陳東旭，專利號：ZL201310350098.9。

5、一種替馬羅汀的合成方法，朱鋼國、李英龍、金雅麗、金發(fā)根、吳平、樓益義，專利號：ZL 201310362839.5。

6、一種奧司他韋的合成方法，朱鋼國、杜思全、章潔妮、程存歸，專利申請?zhí)枺篫L 201410102788.7。

1、夏思苑等，指導教師：朱鋼國，雜原子取代炔烴的氫鹵化反應研究及其應用，第十三屆大學生“挑戰(zhàn)杯”競賽浙江省一等獎；

2、夏思苑等，指導教師：朱鋼國，高效綠色合成抗禽流感藥物“達菲”原料的技術研究，第十三屆大學生“挑戰(zhàn)杯”競賽全國二等獎。