學(xué)術(shù)背景
湖南大學(xué) 教授
紐約市哥倫比亞大學(xué)醫(yī)學(xué)中心 博士后研究科學(xué)家（Postdoctoral Research Scientist）
新加坡國立大學(xué) 研究員（Research Fellow）
新加坡國立大學(xué) 博士研究生
學(xué)術(shù)兼職
1、中國醫(yī)學(xué)裝備協(xié)會轉(zhuǎn)化醫(yī)學(xué)分會委員
2、中國生物醫(yī)學(xué)工程學(xué)會組織工程與再生醫(yī)學(xué)分會理事會青年委員
3、湖南省生物材料學(xué)會理事
4、《Current Smart Materials》編委
5、湖南省及長沙市醫(yī)療器械行業(yè)協(xié)會專家
研究領(lǐng)域
課題組的研究興趣包括以下三方面：
1、干細(xì)胞體內(nèi)遷移與細(xì)胞治療的機(jī)制研究（Cell homing and therapy mechanisms）
2、利用生物材料構(gòu)建細(xì)胞微環(huán)境（Engineering of cell niche）
3、組織（毛囊、腎臟、神經(jīng)）再生（Regeneration of hair follicle,glomerularfiltrationmembrane, neuron）
科研項目
1、長沙市重點研發(fā)計劃項目，kq1901024，2018/07-2021/06，主持人。
2、湖南省重點研發(fā)計劃項目，2018SK2106，2018/01-2020/12，主持人。
3、國家自然科學(xué)基金面上項目，31670997，2017/01-2020/12，主持人。
4、深圳市科創(chuàng)委基礎(chǔ)研究（自由探索）項目，JCYJ20160530193417959，2016/09-2018/08，主持人。
5、湖南省自然科學(xué)杰出青年基金，2015JJ1007，2015/01-2017/12，主持人。
6、湖南大學(xué)交叉學(xué)科項目，2015JCA02，2015/01-2017/12，主持人。
7、國家自然科學(xué)基金青年基金項目，31200727，2013/01-2015/12，主持人。
學(xué)術(shù)成果
1. Lin Lan, Qiuping Guo,Hemin Nie, Chang Zou, Qingyun Cai, Jin Huang, Xiangxian Meng, Linear-hairpin variable primer RT-qPCR for MicroRNA.Chemical Science, 2019, 10, 2034-2043.
2. Bei Xie, Wanzong Zhu, Pinghui Ding, Mengting Chen, Ji Li, Lei Lei, Can Zhang,Hemin Nie (*), Nanofiber scaffolds attenuate collagen synthesis of human dermal fibroblasts through TGF-β1/TSG-6 pathway,Journal of Physics: Materials, 2019, 2, 044001 (DOI: 10.1088/2515-7639/ab2563).
3. Can Zhang, Bei Xie, Yujian Zou, Dan Zhu, Lei Lei, Dapeng Zhao,Hemin Nie (*), Zero-dimensional, one-dimensional, two-dimensional and three-dimensional biomaterials for cell fate regulation,Advanced Drug Delivery Reviews, 2018, 132, 33-56.
4. Qian Li, Yun Bai, Tao jin, Shuo Wang, Wei Cui, Ilinca Stanciulescu, Rui Yang,Hemin Nie (*), Linshan Wang (*), Xing Zhang (*), Bioinspired engineering of poly(ethylene glycol) hydrogels and natural protein fibers for layered heart valve constructs,ACS Applied Materials & Interfaces, 2017, 9, 16524-16535.
5.Hemin Nie (*), Jeremy J. Mao, Micro-/nanotech-based craniofacial tissue engineering,Handbook of Intelligent Scaffolds for Tissue Engineering and Regenerative Medicine(2nd Edition), Gilson Khang, Pan Stanford Publishing, pp 660-675, United States, 2017.
6. Bei Xie, Jipeng Yi, Jian Peng, Xing Zhang, Lei Lei, Dapeng Zhao, Zhixin Lei,Hemin Nie (*), Characterization of synergistic anti-tumor effects of doxorubicin and p53 via graphene oxide-polyethyleneimine nanocarriers,Journal of Materials Science & Technology, 2017, 44, 3372-3383.
7. Cuiping Zhong, Hongwei Shen, Yu Han, Shuo Wang, Ye Wang, Xining Xu, Jianhua Qiu,Hemin Nie (*), Alginate microcapsules co-embedded with MSCs and anti-EGF mAb for the induction of hair cell-like cells in guinea pigs by taking advantage of host EGF,Journal of Materials Chemistry B, 2016, 4, 7387-7397.
8. Bei Xie, Jian Peng, Shuo Wang, Xing Zhang,Hemin Nie (*), Investigation of the sequential actions of doxorubicin and p53 on tumor cell growth via branched polyethylenimine-β-cyclodextrin conjugates,Annals of Biomedical Engineering, 2016, 4, 3372-3383.
9. Dapeng Zhao, Lei Lei, Shuo Wang,Hemin Nie (*),Understanding cell homing-based tissue engineering from the perspective of materials,Journal of Materials Chemistry B, 2015, 3, 7319-7333.
10. Shuo Wang (#), Shaoping Zhong (#), Chew Teck Lim (*),Hemin Nie (*), Effects of fiber alignment on stem cellu2013fibrous scaffold interactions,Journal of Materials Chemistry B, 2015, 3, 3358-3366.
11. Shuo Wang, Wei Ju, Peng Shang, Lei Lei,Hemin Nie (*), Coreu2013shell microspheres delivering FGF-2 and BMP-2 in different release patterns for bone regeneration,Journal of Materials Chemistry B, 2015, 3, 1907-1920.
12. Dinggeng He, Shuo Wang, Lei Lei, Zengtao Hou, Peng Shang, Xiaoxiao He,Hemin Nie (*), Coreu2013shell particles for controllable release of drug,Chemical Engineering Science, 2015, 125, 108-120.
13. Lei Lei, Shuo Wang, Honghui Wu, Wei Ju, Jian Peng, Alshurefi Anwarqahtan, Chen Chen, Yanqin Lu, Jieying Peng, Xing Zhang,Hemin Nie (*), Optimization of release pattern of FGF-2 and BMP-2 for osteogenic differentiation of low-population density hMSCs,Journal of Biomedical Materials Research Part A, 2015, 103(1), 252-261.
14.Hemin Nie, Jeremy J. Mao (*), Dental and craniofacial bioengineering,Tissue Engineering: Principles and Practices, John P Fisher, Antonios G Mikos, Joseph D Bronzino, Boca Raton : CRC Press, pp 28-1-28-17, United States, 2013.
15.Hemin Nie, Chang Hun Lee, Jiali Tan, Chuanyong Lu, Avital Mendelson, Mo Chen, Mildred C Embree, Kimi Kong, Bhranti Shah, Shuang Wang, Shoko Cho, Jeremy J Mao (*), Musculoskeletal tissue engineering by endogenous stem/progenitor cells,Cell and Tissue Research, 2012, 347(3), 665-676.
16. Zhenglin Yuan (#),Hemin Nie (#), Shuang Wang, Chang Hun Lee, Ang Li, Susan Y Fu, Hong Zhou, Lili Chen(*), Jeremy J Mao (*), Biomaterial selection for tooth regeneration,Tissue Engineering Part B Review, 2011, 17(5), 373-388.
17.Hemin Nie, Jin Kim, Susan Y. Fu, Jeremy J. Mao (*), Biomaterials Selection for Dental Pulp Regeneration,Comprehensive Biomaterials, Paul Ducheyne, Kevin Healy, Dietmar Hutmacher, Elsevier, pp 245-254, United States, 2011.
18.Hemin Nie, Yilong Fu, Chi-Hwa Wang (*), Paclitaxel and suramin-loaded core/shell microspheres in the treatment of brain tumors,Biomaterials, 2010, 31(33), 8732-8740.
19.Hemin Nie, Zhenguo Dong, Davis Yohanes Arifin, Yong Hu, Chi-Hwa Wang (*), Core/shell microspheres via coaxial electrohydrodynamic atomization for sequential and parallel release of drugs,Journal of Biomedical Materials Research Part A, 2010, 95(3), 709-716.
20.Hemin Nie, Shih Tak Khew, Lai Yeng Lee, Kai Ling Poh, Yen Wah Tong, Chi-Hwa Wang (*), Lysine-based peptide-functionalized PLGA foams for controlled DNA delivery,Journal of Controlled Release, 2009, 138(1), 64-70.
21.Hemin Nie, Mei-Ling Ho, Chih-Kuang Wang, Chi-Hwa Wang, Yin-Chih Fu (*), BMP-2 plasmid loaded PLGA/HAp composite scaffolds for treatment of bone defects in nude mice,Biomaterials, 2009, 30(5), 892-901.
22.Hemin Nie, Lai Yeng Lee, Hui Tong, Chi-Hwa Wang (*), PLGA/chitosan composites from a combination of spray drying and supercritical fluid foaming techniques: New carriers for DNA delivery,Journal of Controlled Release, 2008, 129(3), 207-214.
23.Hemin Nie, Beng Wee Soh, Yin-Chih Fu, Chi-Hwa Wang (*), Three-dimensional fibrous PLGA/HAp composite scaffold for BMP-2 delivery,Biotechnology and Bioengineering, 2008, 99(1), 223-234.
24. Yin-Chih Fu,Hemin Nie, Mei-Ling Ho, Chih-Kuang Wang, Chi-Hwa Wang (*), Optimized bone regeneration based on sustained release from three-dimensional fibrous PLGA/HAp composite scaffolds loaded with BMP-2,Biotechnology and Bioengineering, 2008, 99(4), 996-1006.
25.Hemin Nie, Chi-Hwa Wang (*), Fabrication and characterization of PLGA/HAp composite scaffolds for delivery of BMP-2 plasmid DNA,Journal of Controlled Release, 2007, 120(1-2), 111-121.
獎勵
2019年甘肅省科技進(jìn)步二等獎（排名第二）
項目名稱：組織工程干細(xì)胞在感音神經(jīng)性耳聾中的作用研究
