個(gè)人簡(jiǎn)介
代表性成果（專業(yè)成果、學(xué)術(shù)論文、學(xué)術(shù)專著等）：
部分論文列表
1. Zhao J, Ding J, Li YQ, Ren KQ, Sha JH, Zhu MS, *Gao X (2009) HnRNP U mediates the long-range regulation of Shh expression during limb development. Hum Mol Genet. in press
2. Wang Q, Jiang L, Wang J, Li S, Yu Y, You J, Zeng R, Gao X, Rui L, Li W, Liu Y (2009) Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. Hepatology. In press
3. Lin C, Jiang X, Dai Z, Guo X, Weng T, Wang J, Li Y, Feng G, *Gao X, *He L (2009) Sclerostin mediates bone response to mechanical unloading via antagonizing Wnt/b-catenin signaling. J Bone Miner Res, in press
4. Ding J, Gao Y, Zhao J, Yan H, Guo SY, Zhang QX, Li LS, *Gao X（2009）Pax6 haploinsufficiency causes abnormal metabolic homeostasis by down-regulating GLP-1 in mice. Endocrinology, in press
5. Wen JH, Chen YY, Song SJ, Ding J, Gao Y, Hu QK, Feng RP, Liu YZ, Ren GC, Zhang CY, Hong TP, *Gao X, and *Li LS (2009) Paired box 6 (PAX6) regulates glucose metabolism via proinsulin processing mediated by prohormone convertase 1/3 (PC1/3). Diabetologia, 52(3):504-13.
6. Wang X, Zhang Y, Xiao G, Gao X, Liu XL (2009) c-Fos enhances survival of thymocytes during positive selection by upregulating Bcl-2. Cell Res. 19:340-7
7. Liu ZP, Zhang CL, Li Y, Wu ZY, Qian F, Yang XL, He WJ, Gao X, Guo Z (2009) A Zn2+ fluorescent sensor derived from 2-(pyridin-2-yl)benzoimidazole with ratiometric sensing potential. Organic letters 11:795-8
8. Qian F, Zhang CL, Zhang Y, He WJ, Gao X, Hu P, Guo ZJ (2009) Visible light excitable Zn2+ fluorescent sensor derived from an intramolecular charge transfer fluorophore and its in vitro and in vivo application. Journal of the American Chemical Society 131:1460-8
9. Zhang YF, Li H, Wang XM, Gao X, Liu XL (2009) Regulation of T cell development and activation by creatine kinase B. PLoS ONE 4:e5000
10. Chen H, Jin H, Du CY, Gu PY, Wang CY, Zhang QX, Gao X（2008）Establishment of transgenic mice expressing SV40T in parietal cells. Acta Anatomica Sinica 39: 699-702
11. Ding XF, Luo C, Ren KQ, Zhang J, Zhou JL, Hu X, Liu RS, Wang Y, *Gao X, *Zhang J (2008) Characterization and expression of a human KCTD1 gene containing the BTB domain, which mediates transcriptional repression and homomeric interactions. DNA and Cell Biology 27: 257-265
12. Ha TZ, Hua F, Liu X, Ma J, McMullen JR, Shioi T, Izumo S, Kelley J, Gao X, Browder W, Williams DL, Kao RL, Li CF (2008) Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovascular Research 78:546-53
13. Zeng H, Chen Y, Yu M, Xue L, Gao X, Morris SW, Wang D, Wen R (2008)TCR-mediated activation of CD4+CD44hi T cells bypasses Bcl10： An implication of differential NF-κB dependence of naïve and memory T cells during TCR-mediated responses. J Biol Chem, 283(36):24392-9
14. Wang XM, Xiao G, Zhang YF, Wen XM, Gao X, Okada S, Liu X (2008) Regulation of Tcrb recombination ordering by c-Fos-dependent RAG deposition Nature Immunology, 9(7):794-801
15. He WQ, Peng YJ, Zhang WC, Lv N, Tang J, Chen C, Zhang CH, Gao S, Chen HQ, Zhi G, Feil R, Kamm KE, Stull JT, *Gao X, Zhu MS (2008) Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice. Gastroenterology, 135(2):610-20.
16. Xiong X, Qi X, Ge XM, Gu P, Zhao J, Zhao QS, *Gao X.(2008) A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice. J Biomed Sci, 15:47-59
17. Sun L, Ma K, Wang H, Xiao F, Gao Y, Zhang W, Wang K, Gao X, Ip N and Wu Z (2007) JAK1-STAT1-STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts. J Cell Biol. 179: 129-138
18. Sha HB, Xu J, Tang J, Ding J, Gong JF, Ge XM, Kong D, *Gao X. (2007) Disruption of a novel regulatory locus results in decreased Bdnf expression, obesity and type 2 diabetes in mice. Physiological Genomics, 31:252-63
在研項(xiàng)目
國(guó)家自然科學(xué)基金國(guó)際(地區(qū))合作與交流項(xiàng)目---在體研究JAK1 在骨骼肌干細(xì)胞及肌肉再生中的功能
國(guó)家杰出青年科學(xué)基金---運(yùn)用基因組改造建立小鼠疾病模型及開展分子機(jī)理研究
國(guó)家支撐計(jì)劃項(xiàng)目課題---基因剔除小鼠模型的疾病表型分析技術(shù)及其標(biāo)準(zhǔn)化研究
國(guó)家重點(diǎn)基礎(chǔ)研究發(fā)展計(jì)劃973課題---小鼠聽力、視力等神經(jīng)系統(tǒng)遺傳缺陷的分子機(jī)制
獲獎(jiǎng)情況
首屆華僑華人專業(yè)人士“杰出專業(yè)獎(jiǎng)”
2006年江蘇省科技進(jìn)步二等獎(jiǎng)
談家楨生命科學(xué)獎(jiǎng)創(chuàng)新獎(jiǎng)
學(xué)術(shù)兼職
上海交通大學(xué)教授、博導(dǎo)，中國(guó)細(xì)胞生物學(xué)學(xué)會(huì)副理事長(zhǎng)，中國(guó)實(shí)驗(yàn)動(dòng)物學(xué)會(huì)常務(wù)理事，中國(guó)動(dòng)物學(xué)會(huì)理事，國(guó)家科學(xué)技術(shù)名詞審定委員會(huì)遺傳學(xué)委員會(huì)委員，江蘇省發(fā)育生物學(xué)會(huì)理事長(zhǎng)，Cell Research和Genesis雜志編委等。
