研究方向
主要從事林產(chǎn)精細化學品和生物活性物質(zhì)領域的教學和科研工作。重點開展松香樹脂酸等天然萜類物質(zhì)的合成改性及其綜合利用,以及林源藥用植物及其內(nèi)共生菌的天然活性物質(zhì)的基礎及應用研究。
獲獎情況
主持或參與課題
(1)國家自然科學基金(青年基金項目):新型樹脂酸雜環(huán)氮氧化物的合成及其靶向抗腫瘤作用的研究,國家自然科學基金 (31000273), 2011-2013,項目負責人。
發(fā)表論文(代表性或近三年)
1. Wen Gu,Chao Qiao, Shifa Wang, Yun Hao, Tingting Miao. Synthesis and biological evaluation of novel N-substituted 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential antimicrobial agents.Bioorganic & Medincinal Chemistry Letters, In press.
2. Wen Gu,Yun Hao, Hongtu Chen, Shifa Wang. Synthesis, crystal Structure and cytotoxic activity of a new N-Vinyl-1H-dibenzo[a,c]carbazole derivative of dehydroabietic dcid.Chinese Journal of Structural Chemistry, In press.
3. Wen Gu, Chao Qiao. Furandiones from an endophyticAspergillus terreusresiding inMalus halliana.Chemical & Pharmaceutical Bulletins, 2012, 60 (11), 1474-1477.
4. Wen Gu, Rongrong Wu, Shilong Qi, Chenhai Gu, Fanjunnan Si, Zhuhui Chen. Synthesis and antibacterial evaluation of newN-acylhydrazone derivatives from dehydroabietic acid. Molecules, 2012, 17, 4634-4650.
5. Wen Gu,Chao Qiao.N-(4-Bromophenyl)-3,4,5-trimethoxybenzamide. Acta Crystallographica, Sect. E, 2012, E68, o1658.
6. Wen Gu,Shifa Wang. Synthesisand antimicrobial activities of novel 1H-dibenzo[a,c] carbazoles from dehydroabietic acid. European Journal of Medicinal Chemistry, 2010, 45,4692-4696.