2011.4至今 中國(guó)農(nóng)業(yè)大學(xué)副教授

2017.11-2018.11美國(guó)康奈爾大學(xué)訪問(wèn)副教授

2008.11-2011.3 堪薩斯州立大學(xué)生物系博士后

2006.3-2011.3 堪薩斯州立大學(xué)生物化學(xué)系博士后

1996.9-2000.6 南開(kāi)大學(xué)本科

2000.9-2005.6 南開(kāi)大學(xué)博士

本科生課程：

1.分子生物學(xué)導(dǎo)論

2.分子生物學(xué)導(dǎo)論實(shí)驗(yàn)

3.普通昆蟲(chóng)學(xué)實(shí)驗(yàn)

4. Basic Biology（英文授課）

研究生課程：

1.昆蟲(chóng)免疫學(xué)

（一）昆蟲(chóng)天然免疫學(xué)

1.基于組學(xué)數(shù)據(jù)，篩選參與昆蟲(chóng)天然免疫反應(yīng)的重要基因。

2.運(yùn)用分子生物學(xué)、生物化學(xué)、細(xì)胞學(xué)、遺傳學(xué)等手段研究外源物入侵后昆蟲(chóng)體液免疫和細(xì)胞免疫反應(yīng)被激活和調(diào)控的分子機(jī)制。

（二）害蟲(chóng)生物防治

1.研究昆蟲(chóng)病原菌或線蟲(chóng)對(duì)昆蟲(chóng)天然免疫的影響。

2.基于對(duì)昆蟲(chóng)天然免疫反應(yīng)能力的破壞或削弱，研究對(duì)害蟲(chóng)的生物防治。

主持或參加國(guó)家自然科學(xué)基金、科技部、教育部、農(nóng)業(yè)部基金項(xiàng)目九項(xiàng)。

近年主持項(xiàng)目：

1)國(guó)家自然科學(xué)基金面上項(xiàng)目（31172090）， 2012-2016年， 主持人

2) 教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃（NCET-11-0476）， 2013-2015年，主持人

3) 國(guó)家“973”計(jì)劃項(xiàng)目（2013CB114102），2014-2016年，研究骨干

4）中國(guó)農(nóng)業(yè)大學(xué)人才引進(jìn)科研啟動(dòng)項(xiàng)目，2011-2014年，主持人

5）中央高�；�本科研業(yè)務(wù)費(fèi)資金項(xiàng)目（2011JS073），2011年-2012年，主持人

6） 國(guó)家自然科學(xué)基金面上項(xiàng)目：絲氨酸蛋白酶SP8和SP105在亞洲玉米螟黑化反應(yīng)中的功能和作用機(jī)制研究62萬(wàn)元

7）國(guó)家自然科學(xué)基金面上項(xiàng)目：胰島素及其受體對(duì)果蠅行為節(jié)律的調(diào)控59萬(wàn)元

8）教育部新世紀(jì)優(yōu)秀人才支持計(jì)劃項(xiàng)目：果蠅黑化反應(yīng)的激活和調(diào)控機(jī)制50萬(wàn)元

已在國(guó)內(nèi)外發(fā)表學(xué)術(shù)論文59篇，其中以第一或通訊作者發(fā)表SCI論文13余篇；參編研究專(zhuān)著1部。

1) He, B., Chu, Y., Yin, M.*, Müllen, K., An, C.*, Shen, J*. (2013) Fluorescent nanoparticle delivered dsRNA toward genetic control of insect pests. Adv. Mater. DOI: 10.1002/adma.201301201 (IF: 14.829)

2) An, C.*, Zhang, M., Chu, Y., Zhao, Z.*. (2013) Serine protease MP2 activates prophenoloxidase in the melanization immune response of Drosophila melanigaster. PLos One, DOI: 10.1371/ journal.pone.0079533 (IF: 3.73)

3) Zhang, M., Zhou, F., Chu, Y., Zhao, Z., An, C*. (2013) Identification and expression profile analysis of antimicrobial peptide/protein in Asian corn borer, Ostrinia furnacalis (Gunée), Int. J. Biol. Sci. 9(9): 1004-1012. (IF: 3.168)

4) An, C., Fei, X., Chen, W., Zhao, Z.*. (2012) The integrative effects of population density, photoperiod, temperature, and host plant on the induction of alate aphids in Schizaphis graminum. Arch. Insect Biochem. 79(4):198-206.

5) An, C., Hiromasa, Y., Zhang, X., Lovell, S., Zolkiewski, M., Tomich, JM., Michel, K.*. (2012) Biochemical characterization of Anopheles gambiae SRPN6, a malaria parasite invasion marker in mosquitoes. PLos one. 7(11): e48689.

6)An, C., Budd, A., Kanost, M.R., Michel. K*., (2011) Characterization of a regulatory unit that controls melanization and affects longevity of mosquitoes. Cel. Mol. Life Sci. 68(11):1929-1939.

7)An, C., Ragan, E. J., Kanost, M. R*. (2011) Serpin-1 splicing isoform J inhibits the proSp?tzle-activating proteinase HP8 to regulate expression of antimicrobial hemolymph proteins in Manduca sexta. Dev. Comp. Immunol. 35, 135-141.

8)An, C, Lovell, S., Kanost, M.R., Battaile, K. P., Michel, K*. (2011) Crystal structure of native Anopheles gambiae Serpin-2, a negative regulator of melanization in mosquitoes. Proteins. 79(6), 1999-2003.

9)Ragan, E.J., An, C. (Co-first author), Yang, C., Kanost, M.R. (2010) Analysis of mutually-exclusive alternatively spliced serpin-1 isoforms and identification of Serpin-1 proteinase complexes in Manduca sexta hemolymph. J. Biol. Chem. 285(38): 29642-29650.

10)An, C., Kanost, M.R. (2010) Manduca sexta serpin-5 regulates prophenoloxidase activation and the Toll signaling pathway by inhibiting hemolymph proteinase HP6. Insect Biochem. Mol. Biol. 40, 683-689.

11)An. C, Jiang, H., Kanost, M.R. (2010) Proteolytic activation and function of the cytokine Sp?tzle in the innate immune response of a lepidopteran insect, Manduca sexta. FEBS J. 277, 148-162.

12)An. C., Ishibashi, J., Ragan, E.J., Jiang, H., Kanost, M.R. (2009) Functions of Manduca sexta hemolymph proteinases HP6 and HP8 in two innate immune pathways. J. Biol. Chem. 284, 19716-19726.

13)Ragan, E.J., An, C., Jiang, H., Kanost, M.R. (2009) Roles of haemolymph proeins in antimicrobial defences of Manduca sexta. In: Insect Infection and Immunity (J. Rolff and S. E. Reynolds, eds) pp34-48, Oxford University Press. (Book)

14)Pinto, S.B., Lombardo, F., Koutsos, A.C., Waterhouse, R. M., McKay, K., An, C., Ramakrishnan, C., Kafatos, F. C., Michel, K. (2009) Discovery of Plasmodium modulators by genome-wide analysis of circulating hemocytes in Anopheles gambiae. PNAS. 106, 21270-21275.

15)Gorman, J., An, C., Kanost, M.R. (2007) Characterization of tyrosine hydroxylase from Manduca sexta. Insect Biochem. Mol. Biol. 37, 1327-1337. (IF: 3.12)

16）. Shen, D., Wang, L., Liu, Q.,An, C*. 2018. Identification and characterization of C-type lectins in Asian corn borer,Ostrinia furnacalis(Guenée).J. Insect. Sci.18(2):1-11.

17）Chu, Y., Hong, F., Liu, Q.,An. C*. 2017. Serine protease SP105 activates prophenoloxidase in Asian corn borer melanization, and is regulated by serpin-3.Sci. Rep.7: 45256. doi: 10.1038/srep45256.

18）Shen, D., Li, M., Chu, Y., Lang, M.,An, C*. 2016. Cellular immune response of Asian corn borer,Ostrinia furnacalis(Guenée), to the infection of entomopathagenic fungusBeauveria bassiana.Eur. J. Entomo.113:415-422.

19） Chu, Y., Liu, Y., Shen, D., Hong, F., Wang, G.,An. C*. 2015. Serine proteases SP1 and SP13 mediate the melanization response of Asian corn borer,Ostrinia furnacalis, against entomopathogenic fungusBeauveria bassana.J. Invert. Path.128, 64-72.

20） Chu, Y., Zhou, F., Liu, Y., Hong, F., Wang, G.,An. C*. 2015.Ostrinia furnacalisserpin-3 regulates melanization cascade by inhibiting a prophenoloxidase-activating protease.Insect Biochem. Mol. Biol. 61, 53-61.

21） Shen, D., Liu, Y., Zhou, F., Wang, G.,An, C*. 2014. Identification of immunity-related genes inOstrinia furnacalisagainst entomopathogenic fungi by RNA-Seq analysis. PlosOne. 9(1), e86436.

22）Shen, D., Zhou, F., Xu, Z., He, B., Li, M., Shen, J., Yin, M.,An, C*. 2014. Systemically interfering with immune response by a fluorescent cationic dendrimer delivered gene suppression.J. Mater. Chem. B.2,4653-4659.