人物經(jīng)歷
教育經(jīng)歷
1989-1993 湖南大學(xué) 有機(jī)化工 學(xué)士；
1995-1998 湖南大學(xué) 有機(jī)化學(xué) 碩士；
1998-2001 湖南大學(xué) 分析化學(xué) 博士。
工作經(jīng)歷
2001年獲分析化學(xué)博士學(xué)位后留校任教。2003-2005年在法國(guó)里昂高等師范學(xué)校、瑞典皇家工學(xué)院從事生物有機(jī)化學(xué)方向博士后研究，2005年3月加入湖南大學(xué)化學(xué)生物傳感與計(jì)量學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室，2006年起任湖南大學(xué)教授。分別于2008年6-9月以邀請(qǐng)教授的身份到法國(guó)里昂高等師范學(xué)校，2009年2-8月以高級(jí)訪問學(xué)者的身份到美國(guó)伊利諾伊大學(xué)香檳分校從事生物分析領(lǐng)域的科研合作。
學(xué)術(shù)兼職
現(xiàn)任《分析化學(xué)》及《中國(guó)科學(xué)-化學(xué)》編委。
研究領(lǐng)域
新型有機(jī)小分子熒光探針的設(shè)計(jì)與合成；熒光生物探針在生物分析中的應(yīng)用。
科研項(xiàng)目
主持國(guó)家杰出青年科學(xué)基金項(xiàng)目，國(guó)家自然科學(xué)基金面上項(xiàng)目以及國(guó)家“973”計(jì)劃課題等。
學(xué)術(shù)成果
代表性論文：
1. H. Liu, K. Li, X.-X. Hu, L. Zhu, Q. Rong, Y. Liu, X.-B. Zhang*, J. Hasserodt, F.-L. Qu, W. Tan, In situ localization of enzyme activity in live cells by a molecular probe releasing a precipitating fluorochrome, Angew. Chem. Int. Ed. 2017, 56, 11788-11792.
2. Y. Wu, L. Zhang, C. Cui, S. Cansiz, H. Liang, C. Wu, I.-T. Teng, W. Chen, Y. Liu, W. Hou, X.-B. Zhang*, W. Tan*, Enhanced targeted gene transduction: AAV2 vectors conjugated to multiple aptamers via reducible disulfide linkages, J. Am. Chem. Soc. 2018, 140, 2-5.
3. Hong-Min Meng, Hui Liu, Hailan Kuai, Ruizi Peng, Liuting Mo and Xiao-Bing Zhang*, Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy, Chem. Soc. Rev., 2016, 45, 2583-2602.
4. Huanhuan Fan, Guobei Yan, Zilong Zhao, Xiaoxiao Hu, Wenhan Zhang, Hui Liu, Xiaoyi Fu, Ting Fu, Xiao-Bing Zhang* and Weihong Tan*, A Smart Photosensitizer-MnO2 Nanosystem for Enhanced Photodynamic Therapy via Reducing Glutathione Levels in Cancer Cells, Angew. Chem. Int. Ed., 2016, 55, 5477-5482.
5. Yifan Lv, Rong Hu, Guizhi Zhu, Xiao-Bing Zhang*, Lei Mei, Qiaoling Liu, Liping Qiu, Cuichen Wu, Weihong Tan*, Preparation and biomedical applications of programmable and multifunctional DNA nanoflowers, Nature Protocols, 2015, 10, 1508-1524.
6. Zhi-Ling Song, Zhuo Chen*, Xia Bian, Li-Yi Zhou, Ding Ding, Hao Liang, Yu-Xiu Zou, Shan-Shan Wang, Long Chen, Chao Yang, Xiao-Bing Zhang*, and Weihong Tan*, Alkyne-Functionalized Superstable Graphitic Silver Nanoparticles for Raman Imaging, J. Am. Chem. Soc., 2014, 136, 13558-13561.
7. Hao Liang, Xiao-Bing Zhang*, Yifan Lv, Liang Gong, Ruowen Wang, Xiaoyan Zhu,Ronghua Yang* and Weihong Tan*. Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy, Acc. Chem. Res., 2014, 47, 1891-1901.
8. Zilong Zhao, Hongmin Meng, Nannan Wang, Michael J. Donovan, Ting Fu, Mingxu You, Xiao-Bing Zhang*, Weihong Tan*, A Controlled-release Nanocarrier with pHe-driven Targeting and Translocation for Drug Delivery, Angew. Chem. Int. Ed., 2013, 52, 7487-7491.
9. Tao Chen, Cuichen Sam Wu, Elizabeth Jimenez, Zhi Zhu, Joshua G. Dajac, Mingxu You, Da Han, Xiao-Bing Zhang*, and Weihong Tan*, DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy, Angew. Chem. Int. Ed., 2013, 52, 2012-2016.
10. Cuichen Wu, Da Han, Tao Chen, Lu Peng, Guizhi Zhu, Mingxu You, Liping Qiu, Kwame Sefah, Xiaobing Zhang*, Weihong Tan*, Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy. J. Am. Chem. Soc., 2013, 135, 18644-18650.
11. Mingxu You, Yan Chen, Xiao-Bing Zhang*, Haipeng Liu, Ruowen Wang, Kelong Wang, KathrynR.Williams, and Weihong Tan*, An Autonomous and Controllable Light-Driven DNA Walking Device. Angew. Chem. Int. Ed., 2012, 51, 2457-2460.
12. Tao Chen, Ismail Oecsoy, Quan Yuan, Ruowen Wang, Mingxu You, Zilong Zhao, Erqun Song, Xiao-Bing Zhang*, Weihong Tan,* One-Step Facile Surface Engineering of Hydrophobic Nanocrystals with Designer Molecular Recognition, J. Am. Chem. Soc., 2012, 134, 13164-13167.
13. Liu Yang, Ling Meng, Xiao-Bing Zhang*, Yan Chen, Guizhi Zhu, Haipeng Liu, Kwame Sefah and Weihong Tan*, Engineering Polymeric Aptamers for Selective Cytotoxicity. J. Am. Chem. Soc., 2011, 133, 13380-13386.
14. Li-Min Lu, Xiao-Bing Zhang*, Rong-Mei Kong, Bin Yang, Weihong Tan*, Ligation-triggered DNAzyme Cascade for Amplified Fluorescence Detection of Biological Small Molecules with Zero-Background Signal. J. Am. Chem. Soc., 2011, 133, 11686-11691.
獎(jiǎng)勵(lì)榮譽(yù)
2007年入選教育部新世紀(jì)優(yōu)秀人才計(jì)劃項(xiàng)目，
2011年獲湖南省杰出青年科學(xué)基金資助，
2013年獲國(guó)家杰出青年科學(xué)基金資助，
2015年入選湖南省芙蓉學(xué)者特聘教授，
2016年入選湖南省科技領(lǐng)軍人才、國(guó)家中青年科技創(chuàng)新領(lǐng)軍人才，
2017年入選國(guó)家“萬(wàn)人計(jì)劃”科技創(chuàng)新領(lǐng)軍人才、國(guó)家百千萬(wàn)人才工程，并被授予“有突出貢獻(xiàn)中青年專家稱號(hào)”。
