基本內(nèi)容
2002年畢業(yè)于華中科技大學(xué)同濟(jì)醫(yī)學(xué)院預(yù)防醫(yī)學(xué)專業(yè),獲學(xué)士學(xué)位;2007年畢業(yè)于上海交通大學(xué)醫(yī)學(xué)院神經(jīng)生物學(xué)專業(yè),獲博士學(xué)位,上海市優(yōu)秀畢業(yè)生。2007年8月至2009年7月在美國(guó)肯塔基脊髓損傷研究中心進(jìn)行博士后研究;2009-2015年在美國(guó)國(guó)立健康研究院(NIH)從事研究工作。主要研究方向?yàn)榧顾钃p傷后的軸突再生,通過研究影響中樞神經(jīng)軸突再生的因素及其作用機(jī)制,探索脊髓損傷修復(fù)的有效手段。已在SCI收錄期刊上發(fā)表論文多篇,被引用280余次,H-Index為10。
代表性文章:
1. Yu Z#, Yu P#, Chen H and Geller HM. Targeted inhibition of KCa3.1 attenuates TGF-β-induced reactive astrogliosis through the Smad2/3 signaling pathway. Journal of Neurochemistry, 2014, 130(1):41-49 (#co-first author) 2. Yi JH#, Katagiri Y#, Yu P#, Lourie J, Bangayan N, Symes AJ and Geller HM. Receptor protein tyrosine phosphatase σ binds to neurons in the adult mouse brain. Experimental Neuroloy, 2014, 255:12-18 ( #co-first author)
3. Yu P, Pisitkun T, Wang G, Wang R, Katagiri Y, Gucek, M, Knepper MA and Geller HM. Global analysis of neuronal phosphoproteome regulation by chondroitin sulfate proteoglycans. PloS One, 2013, 8(3):e59285. 4. Zhou Z, Yu P, Geller HM and Ober CK. Biomimetic polymer brushes containing tethered acetylcholine analogs for protein and hippocampal neuronal cell patterning. Biomacromolecules. 2013, 14(2):529-537
5. Yu P, Wang H, Katagiri Y and Geller HM. An in vitro model of reactive astrogliosis and its effect on neuron growth. Methods in Molecular Biology, 2012, 814:327-340 (book chapter)
6. Zhou Z, Yu P, Geller HM and Ober CK. The role of hydrogels with tethered acetylcholine functionality on the adhesion and viability of hippocampal neurons and glial cells. Biomaterials, 2012, 33(8): 2473 -2481
7. Yu P, Santiago LY, Katagiri Y, and Geller HM. Myosin II activity regulates neurite outgrowth and guidance in response to chondroitin sulfate proteoglycans. Journal of Neurochemistry, 2012, 120(6):1117 -1128
8. Yu P, Zhang YP, Shields LB, Zheng Y, Hu X, Hill R, Howard R, Gu Z, Burke DA, Whittemore SR, Xu XM, Shields CB. Inhibitor of DNA binding 2 promotes sensory axonal growth after SCI. Experimental Neurology, 2011, 231(1):38-44
9. Susarla BT, Laing ED, Yu P, Katagiri Y, Geller HM, Symes AJ. Smad proteins differentially regulate TGF-β mediated induction of chondroitin sulfate proteoglycans. Journal of Neurochemistry, 2011, 119(4): 868- 878
10. Yu P, Huang L, Zou J, Yu Z, Wang Y, Wang X, Xu L, Liu X, Xu XM, Lu PH. Immunization with recombinant Nogo-66 receptor (NgR) promotes axonal regeneration and recovery of function after spinal cord injury in rats. Neurobiology of Disease, 2008, 32(3):535-542