科研成果
①主持或參與科研情況
主持課題：現(xiàn)主持國(guó)家自然科學(xué)基金和山東省自然科學(xué)基金各一項(xiàng)。
參與課題：近年來(lái)作為主要研究者先后參與國(guó)家自然科學(xué)基金，奧地利自然科學(xué)基金等課題多項(xiàng)。
②獲獎(jiǎng)情況
作為首位人員獲2008年山東省高等學(xué)校自然科學(xué)一等獎(jiǎng)。
連續(xù)三年（2006至2008年）獲山東理工大學(xué)科技進(jìn)步獎(jiǎng)一等獎(jiǎng)。
③論文發(fā)表情況
累計(jì)在國(guó)際重要學(xué)術(shù)期刊等發(fā)表SCI收錄論文60余篇。代表性論文包括：
代表作品
Hong-Fang Ji, Hong-Yu Zhang, Ling-Ling Chen. Why are prion diseases precluded by non-mammals? Trends Biochem. Sci. 2007, 32: 206-208. (SCI,影響因子IF: 14.99)
Hong-Fang Ji, De-Xin Kong, Liang Shen, Ling-Ling Chen, Bin-Guang Ma, Hong-Yu Zhang. Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery. Genome Biol. 2007, 8: R176. (SCI, IF: 6.59)
Hong-Fang Ji, Xue-Juan Li, Hong-Yu Zhang, Natural products and drug discovery. EMBO Rep. 2009, 10: 194-200. (SCI, IF: 7.45)
Hong-Fang Ji, Lei Chen, Hong-Yu Zhang, Organic cofactors participated more frequently than transition metals in redox reactions of primitive proteins. BioEssays 2008, 30: 766-771. (SCI, IF: 5.40)
Hong-Fang Ji, Lei Chen, Ying-Ying Jiang, Hong-Yu Zhang, Evolutionary formation of new protein folds is linked to metallic cofactor recruitment. BioEssays 2009, 31: 975-980 . (SCI, IF: 5.40)
Hong-Fang Ji, Liang Shen, Rita Grandori, Norbert Müller. The effect of heme on the conformational stability of micro-myoglobin. FEBS J. 2008, 275: 89-96. (SCI, IF: 3.40)
Hong-Fang Ji, Hong-Yu Zhang. A theoretical study on Cu(II)-Binding modes and antioxidant activity of mammalian normal prion protein. Chem. Res. Toxicol. 2004, 17: 471-475. (SCI, IF: 3.51)
Hong-Fang Ji, Liang Shen, Hong-Yu Zhang. b-Lactam antibiotics are multipotent agents to combat neurological diseases. Biochem. Biophys. Res. Commun. 2005, 333: 661-663. (SCI, IF: 2.75)
Hong-Fang Ji, Hong-Yu Zhang. A comparative molecular dynamics study on thermostability of human and chicken prion proteins. Biochem. Biophys. Res. Commun. 2007, 359: 790-794. (SCI, IF: 2.75)
Hong-Fang Ji, Liang Shen, Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism. Bioorg. Med. Chem. Lett. 2009, 19: 2453-2455. (IF: 2.60)
