人物經(jīng)歷
工作經(jīng)歷
1996.6-2005.7中國農(nóng)業(yè)科學(xué)院北京畜牧獸醫(yī)研究所;
2005.8-2008.7密蘇里大學(xué)堪薩斯校區(qū)醫(yī)學(xué)院;
2008.11-至今中國農(nóng)業(yè)大學(xué)動物科技學(xué)院。
主要學(xué)術(shù)任職
中國畜牧獸醫(yī)學(xué)會信息技術(shù)分會理事;
《Frontiers in Statistical Genetics and Methodology》期刊編委,《Genetica》、《BMC Genetics》、《BMC Bioinformatics》、《Bioinformatics》、《Heredity》特約審稿人。
主講課程
主講本科生《畜牧生物統(tǒng)計與試驗設(shè)計》、參講研究生《數(shù)量遺傳學(xué)》、《動物育種原理和方法》課程。
研究方向
主要從事關(guān)聯(lián)全基因組分析、基因組選擇、遠(yuǎn)交群體復(fù)雜性狀基因定位理論研究、生物信息學(xué)和數(shù)據(jù)挖掘平臺構(gòu)建和奶牛、豬分子育種研究。
主要貢獻(xiàn)
參加項目
2006.1-2010.12參加“973”課題《抗病和抗逆基因的克隆分析》;
2009.1-2011.12主持“985”工程隊伍建設(shè)優(yōu)秀人才項目;
2010.1-2012.12主持國家自然科學(xué)基金《應(yīng)用基因組結(jié)集信息建立復(fù)雜性狀基因精確定位的新方法》;2010.1-2012.12主持教育部留學(xué)回國人員科研基金項目《基于基因組集成信息建立基因精確定位的新方法》;
2010.1-2012.12:主持北京市自然科學(xué)基金《遠(yuǎn)交群體數(shù)量性狀QTL的貝葉斯壓縮定位》;
2011.1-2013.12:主持教育部新世紀(jì)人才支持項目。
主要論文
1.LiuJ,ZhangY,ZhangQ,WangL,ZhangJ:StudyonmappingquantitativetraitlociforanimalcomplexbinarytraitsusingBayesian-MarkovchainMonteCarloapproach.SciChinaCLifeSci2006,49(6):552-559.
2.YangTL,ZhaoLJ,LiuYJ,LiuJF,ReckerRR,DengHW:Geneticandenvironmentalcorrelationsofbonemineraldensityatdifferentskeletalsitesinfemalesandmales.CalcifTissueInt2006,78(4):212-217.
3.LiuJ,LiuY,LiuX,DengHW:Bayesianmappingofquantitativetraitlociformultiplecomplextraitswiththeuseofvariancecomponents.AmJHumGenet2007,81(2):304-320.
4.LiuJ,PapasianC,DengHW:Incorporatingsingle-locustestsintohaplotypecladisticanalysisincase-controlstudies.PLoSGenet2007,3(3):e46.
5.ZhangF,LiuJ,ChenJ,DengHW:HAPSIMU:ageneticsimulationplatformforpopulation-basedassociationstudies.BMCBioinformatics2008,9:331.
6.LiuYJ,PapasianCJ,LiuJF,HamiltonJ,DengHW:Isreplicationthegoldstandardforvalidatinggenome-wideassociationfindings?PLoSOne2008,3(12):e4037.
7.LiuXG,LiuYJ,LiuJ,PeiY,XiongDH,ShenH,DengHY,PapasianCJ,DreesBM,HamiltonJJetal:AbivariatewholegenomelinkagestudyidentifiedgenomicregionsinfluencingbothBMDandbonestructure.JBoneMinerRes2008,23(11):1806-1814.
8.LiuYJ,LiuXG,WangL,DinaC,YanH,LiuJF,LevyS,PapasianCJ,DreesBM,HamiltonJJetal:Genome-wideassociationscansidentifiedCTNNBL1asanovelgeneforobesity.HumMolGenet2008,17(12):1803-1813.
9.LiuJ,PeiY,PapasianCJ,DengHW:Bivariateassociationanalysesforthemixtureofcontinuousandbinarytraitswiththeuseofextendedgeneralizedestimatingequations.GenetEpidemiol2009,33(3):217-227.
10.ZhangL,LiuJ,DengHW:Amultilocuslinkagedisequilibriummeasurebasedonmutualinformationtheoryanditsapplications.Genetica2009,137(3):355-364.
11.LiuYZ,PeiYF,LiuJF,YangF,GuoY,ZhangL,LiuXG,YanH,WangL,ZhangYPetal:Powerfulbivariategenome-wideassociationanalysessuggesttheSOX6geneinfluencingbothobesityandosteoporosisphenotypesinmales.PLoSOne2009,4(8):e6827.
12.PeiYF,ZhangL,LiuJ,DengHW:Multivariateassociationtestusinghaplotypetrendregression.AnnHumGenet2009,73(Pt4):456-464.
13.GaoH,FangM,LiuJ,ZhangQ:BayesianshrinkagemappingformultipleQTLinhalf-sibfamilies.Heredity2009,103(5):368-376.
14.JiangL,LiuJ,SunD,MaP,DingX,YuY,ZhangQ:GenomewideassociationstudiesformilkproductiontraitsinChineseHolsteinpopulation.PLoSOne2010,5(10):e13661.(同等第一)
15.ZhangZ,LiuJ,DingX,BijmaP,deKoningDJ,ZhangQ:Bestlinearunbiasedpredictionofgenomicbreedingvaluesusingatrait-specificmarker-derivedrelationshipmatrix.PLoSOne2010,5(9).
16.HuF,LiuJF,ZengZB,DingXD,YinCC,GongYZ,ZhangQ:QTLIdentificationUsingCombinedLinkageandLinkageDisequilibriumMappingforMilkProductionTraitsonBTA6inChineseHolsteinPopulation.Asian-AustJAnimSci2010,23(10):1261u20131267.
17.LuX,LiuJF,GongYF,WangZP,LiuY,ZhangQ:MappingquantitativetraitlociforTlymphocytesubpopulationsinperipheralbloodinswine.BMCGenet2011,12:79.(同等第一)
18.FangM,LiuJ,SunD,ZhangY,ZhangQ,ZhangY,ZhangS:QTLmappinginoutbredhalf-sibfamiliesusingBayesianmodelselection.Heredity2011,107(3):265-276.(同等第一)
19.JiangJ,JiangL,ZhouB,FuW,LiuJF,ZhangQ:Snat:aSNPannotationtoolforbovinebyintegratingvarioussourcesofgenomicinformation.BMCGenet2011,12:85.(通訊)
20.ZhangZ,DingX,LiuJ,ZhangQ,deKoningDJ:Accuracyofgenomicpredictionusinglow-densitymarkerpanels.JDairySci2011,94(7):3642-3650.
21.LuX,GongYF,LiuJF,WangZP,HuF,QiuXT,LuoYR,ZhangQ:Mappingquantitativetraitlociforcytokinesinthepig.AnimGenet2011,42(1):1-5.
22.LiuY,LuX,LuoYR,ZhouJP,LiuXY,LiuJF,DingXD,ZhangQ:Molecularcharacterizationandassociationanalysisofporcineinterferonregulatoryfactor1gene.MolBiolRep2011,38(3):1901-1907.
著作軟件
肉牛雜交遺傳評估系統(tǒng)V1.0。
;蚪M單核苷酸多態(tài)性單機注釋系統(tǒng)V1.0;蚪M單核苷酸多態(tài)性在線注釋系統(tǒng)V1.0。