學(xué)習(xí)與工作經(jīng)歷
1982年，理學(xué)學(xué)士，蘭州大學(xué)化學(xué)系 1987年，理學(xué)碩士，蘭州大學(xué)化學(xué)系 1992年，理學(xué)博士，蘭州大學(xué)化學(xué)系 1982-1993蘭州大學(xué)化學(xué)系，助教，講師。 1993-1995清華大學(xué)化學(xué)系從事博士后研究。 1996-1998美國(guó)Rutgers大學(xué)植物系，訪問學(xué)者。 2001-2002美國(guó)Ohio州立大學(xué)化學(xué)系，高級(jí)訪問學(xué)者。 2005-2006美國(guó)South Carolina大學(xué)化學(xué)與生物化學(xué)系，訪問教授。 1995-至今清華大學(xué)化學(xué)系，副教授，教授。 兼職 清華大學(xué)生命有機(jī)磷化學(xué)及化學(xué)生物學(xué)教育部重點(diǎn)實(shí)驗(yàn)室副主任。 第十屆北京市政協(xié)委員。 《Pharmazie》編委（2006－）。
研究方向
天然產(chǎn)物化學(xué)，有機(jī)合成化學(xué)，化學(xué)生物學(xué)。 主要研究領(lǐng)域 生物活性天然產(chǎn)物的結(jié)構(gòu)，化學(xué)修飾，生物轉(zhuǎn)化和構(gòu)效關(guān)系 生物小分子的化學(xué)進(jìn)化及其仿生機(jī)理 糖生物綴合物、磷酰化肽、肽庫等的化學(xué)合成及其生物學(xué)功能 主講課程 本科生：有機(jī)化學(xué)，有機(jī)合成設(shè)計(jì)，天然產(chǎn)物化學(xué)。 研究生：立體有機(jī)化學(xué)，天然有機(jī)化學(xué)。 研究成果和獲得獎(jiǎng)勵(lì) 作為課題負(fù)責(zé)人和主要工作者，先后承擔(dān)完成國(guó)家自然科學(xué)基金“七.五”重大項(xiàng)目和“八.五”重點(diǎn)項(xiàng)目各1項(xiàng)，主持國(guó)家自然科學(xué)基金項(xiàng)目3項(xiàng)。 榮獲教育部自然科學(xué)獎(jiǎng)二等獎(jiǎng)1項(xiàng)（2003），國(guó)家教委科技進(jìn)步獎(jiǎng)二等獎(jiǎng)（1995），三等獎(jiǎng)（1997）各1項(xiàng)，甘肅省科技進(jìn)步獎(jiǎng)二等獎(jiǎng)1項(xiàng)（1993）。 主編出版《有機(jī)合成化學(xué)與路線設(shè)計(jì)》（清華大學(xué)出版社，2002）�！读着c生命化學(xué)》（清華大學(xué)出版社，第8章，2005）。《現(xiàn)代有機(jī)合成試劑》（化學(xué)工業(yè)出版社，2006）。 在國(guó)內(nèi)外重要學(xué)術(shù)刊物上發(fā)表研究論文90余篇。
合作單位
美國(guó) New Jersey State Rutgers University 植物系 美國(guó) Ohio State University 化學(xué)系 美國(guó) University of South Carolina 化學(xué)與生物化學(xué)系 蘭州大學(xué)功能有機(jī)分子化學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室 國(guó)際學(xué)術(shù)交流 第四屆國(guó)際雜原子學(xué)術(shù)大會(huì)(口頭報(bào)告，韓國(guó)：漢城，1995.8.4-8.7)。 美國(guó) Rutgers 大學(xué)植物系合作研究 (1996.9-1998.3)。 美國(guó) Ohio 州立大學(xué)化學(xué)系合作研究 (2001.7-2002.7)。 第225屆美國(guó)化學(xué)會(huì)年會(huì)、順訪(口頭報(bào)告，美國(guó)：新奧爾良；Ohio州立大學(xué)，2003.3.22-4.5)。
近期發(fā)表主要論文目錄2000-至今
1. Ji SH, Xiao Q, Ju Y(巨勇), Zhao YF, Synthesis of novel dimeric steroidal nucleoside phosphoramidates, Chemistry Letters, 2005, 34(7), 944-945. 2. Liu MJ, Wang Z, Ju Y(巨勇), Wong RNS, Wu QY. Diosgenin induces cell cycle arrest and apoptosis-Inducing Effects of Diosgenyl Saponins on Human Leukemia Cell Lines. Biological & Pharmaceutical Bulletin. 2004, 27 (7) 1059-1065. 4. Li HY, Byeon IJL, Ju Y(巨勇), Tsai MD, Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions, Journal of Molecular Biology, 2004, 335(1), 371-381. 5. Tan B, Lee MC, Cui M, Liu T, Chen ZZ, Li YM, Ju Y(巨勇), Zhao YF, Chen KX, Jiang HL, A common intermediate for prebiotic synthesis of proteins and nucleosides: a density functional theory (DFT) study on the formation of penta-coordinate phosphorus carboxylicu2013phosphoric mixed anhydride from N-phosphoryl amino acids, Journal of Molecular Structure (Theochem) 2004, 672,51u201360. 6. Xiao Q, Sun J, Sun Q, Ju Y(巨勇), Zhao YF, Cui YX, Synthesis of AZT 5u2019-O-Hydrogen phospholipid and their derivatives, Synthesis-Stuttgart, 2003, (1), 107-111. 7. Xiao Q, Ju Y(巨勇), Yang XP, Zhao YF, Electrospray ionization mass spectrometry of AZT H-phosphonates conjugated with steroids, Rapid Communications in Mass Spectrometry, 2003, 17(13), 1405u20131410 8. Wang SF, Ju Y(巨勇), Chen XG, Hu ZD, Separation and determination of coumarins in the root bark of three Citrus plants by micellar electrokinetic capillary chromatography, Planta Medica, 2003, 69(5), 483-486 9. Xiao Q, Ju Y(巨勇), Zhao YF, A facile approach to phosphonic acid diesters, Heteroatom Chemistry, 2003, 14(3), 208-210. 10. Qin ZH, Lin CX, Ju Y(巨勇), Zhao YF, Synthesis of serine/alanine conjugated 3u2019, 5u2019- TpT, Nucleosides, Nucleotides & Nucleic Acids, 2003, 22(1), 63-69. 11. Xiao Q, Sun J, Ju Y(巨勇), Zhao YF, Cui YX, Facile synthesis of 3β-cholesterol H-phosphonates, Chemistry Letters, 2003, 32(6), 522-523. 12. Xiao Q, Ju Y(巨勇), Zhao YF, One-pot Synthesis of the H-phosphonate of AZT and diosgenin, Chemical Journal of Chinese Universities, 2003, 24(8), 1427-1429 (in Chinese). 13. Xiao Q, Ju Y(巨勇), Zhao YF, A convenient route to symmetric phosphate, phosphorothioate and phosphoroselenoate of AZT and D4T, Synthetic Communications, 2003, 33(23), 4157-4162. 14. Xiao Q, Sun J, Ju Y(巨勇), Zhao YF, Cui YX, Facile synthesis of bivalent ligand-based phosphoramidates of AZT, Journal of Chemical Research, 2003, (5), 262-263. 15. Xiao Q, Ju Y(巨勇), Zhao YF, Cui YX, Characteristic fragmentation behavior of phosphoamino acid conjugates with 3u2019-azido-3u2019 -deoxythymidine by electrospray ionization tandem mass spectrometry, Rapid Communications in Mass Spectrometry, 2003, 17(20), 2273-2278. 16. Wang SF, Chen XG, Hu ZD, Ju Y(巨勇), Analysis of three effective components in Fructus corni and its preparations by micellar electrokinetic capillary chromatography, 2003, 17(5), 306-311. 17. Wang SF, Wu YQ, Ju Y(巨勇), Chen XG, Zheng WJ, Hu ZD, On-line concentration by field-enhanced sample injection with reverse migrating micelles in micellar electrokinetic capillary chromatography A, 2003,1017 (1-2), 27-34. 18. Qin DY, Lee H, Yuan CH, Ju Y(巨勇), Tsai MD, Identification of Potential Binding Sites for the FHA Domain of Human Chk2 by in vitro Binding Studies, Biochemical & Biophysical Research Communications, 2003, 311 (4), 803-808. 19. Xiao Q, Sun J, Ju Y(巨勇), Zhao YF, Cui YX, Novel approach to the synthesis of AZT 5u2019-O-hydrogen phospholipids, Tetrahedron induced by dioscin in hela cells, Biological Pharmaceutical Bulletin, 2002,25(2), 193-196. 22. Ju Y(巨勇), Still CC, Sacalis JN, Li J and Ho CT, Cytotoxic coumarins and lignans from extracts of the northern prickly ash, Phytotherapy Research, 2001, 15, 441-443. 23. Hu JJ, Ju Y(巨勇), Zhao Y F, Stereo effect of the peptide formation reaction of N- (O, O-diisopropyl) phosphoryl serine, Chemical Journal Chinese Universities, 2001, 22(3), 399-402 (in Chinese). 24. Wang Z, Zhou JB, Ju Y(巨勇), Zhang H, Liu MJ, Li X, Effects of two saponins extracted from the Polygonatum zanlanscianense on the human leukemia (HL-60) cells, Biological Pharmaceutical Bulletin, 2001,24(2), 159-162. 25. Ju Y(巨勇), Hu JJ, Zhao YF, Reaction of carbohydrates and pentacoordinate oxaphosphorane and their biomimetic mechanism, Phosphorus, Sulfur, Silicon and other Element, 2000,167, 93-100. 26. Hu JJ, Ju Y(巨勇), Zhao YF, Novel synthesis of tri- and penta-coordinate phosphorous saccharides, Synthetic Communication, 2000, 30 (22), 4087-4092. 27. Hu JJ, Ju Y(巨勇), Zhao YF, LC-MS analysis of the formed peptides from N- (O, O-diisoprpyl) phosphoryl aspartic acid, Chinese Journal of Chemistry, 2000, 18(6), 932-935. 28. Hu JJ, Ju Y(巨勇), Zhao YF, Studies on reaction of between N-phosphoryl amino acids and ribotides, Chemical Journal of Chinese Universities, 2000, 21(11), 1667-1670 (in Chinese).
