1987.9—1994.6 　武漢大學(xué)化學(xué)系高分子化學(xué)與物理專業(yè)學(xué)習(xí), 獲理學(xué)學(xué)士、碩士學(xué)位，導(dǎo)師：張俐娜院士；

1994.9—1997.6 　中山大學(xué)高分子研究所高分子化學(xué)與物理專業(yè)學(xué)習(xí), 獲理學(xué)博士學(xué)位，導(dǎo)師：李卓美教授；

2000.3—2004.3 日本國(guó)家產(chǎn)業(yè)技術(shù)綜合研究所(National Institute of Advanced Industrial Science and Technology, AIST)，日本學(xué)術(shù)振興會(huì)(JSPS)博士后和AIST博士后

1997.7—2000.2 廣州市輕工研究所，工程師；

2004.4—今 中山大學(xué)化學(xué)學(xué)院高分子研究所，副教授

研究生課程：《天然高分子與生物高分子》、《高分子結(jié)構(gòu)與性能的現(xiàn)代測(cè)試技術(shù)》（光散射實(shí)驗(yàn)技術(shù)）；

本科生課程：《現(xiàn)代化學(xué)實(shí)驗(yàn)與技術(shù)（物理化學(xué)實(shí)驗(yàn)部分）》、《功能高分子材料》、《大學(xué)化學(xué)實(shí)驗(yàn)》。

天然高分子改性及其功能化：

(1)天然多糖的高分子結(jié)構(gòu)及其對(duì)生物活性的影響

(2)天然多糖的化學(xué)修飾及其生物醫(yī)用功能化

作為項(xiàng)目負(fù)責(zé)人承擔(dān)的項(xiàng)目：

(1) 廣東省自然科學(xué)基金重點(diǎn)項(xiàng)目（2017B030311007）：茶多糖對(duì)血糖調(diào)控酶活性的影響及其作用機(jī)制研究，2017.05-2020.05

(2)廣東省公益研究與能力建設(shè)專項(xiàng)（2016A020222017）：兩親性殼聚糖衍生物復(fù)合納米粒的制備及其智能調(diào)控胰島素釋放的研究，2016.1-2018.12

(3)廣州市科技計(jì)劃項(xiàng)目（201607010249）：小腸靶向高效吸收的多糖載藥納米粒研究，2016.4-2019.3

(4) 國(guó)家自然科學(xué)基金專項(xiàng)基金項(xiàng)目（科學(xué)部主任基金）（21244005）：超支化茶多糖化學(xué)改性用作胰島素基因轉(zhuǎn)染載體的研究，2013.1-2013.12

(5) 國(guó)家自然科學(xué)基金面上項(xiàng)目（20974130）：基于“樹枝”狀兩親性支鏈淀粉衍生物的單分子反膠束研究，2010.1-2012.12

(6) 國(guó)家自然科學(xué)基金面上項(xiàng)目（20574089）：新型兩親性直鏈淀粉衍生物的合成及其膠束化行為，2006.1-2008.12

(7) 霍英東教育基金第十屆高等院校青年教師優(yōu)選資助課題基金（104036）：茶多糖對(duì)預(yù)防心臟性猝死的保健功效，2006.3-2009.2

(8) 教育部高校基本科研業(yè)務(wù)費(fèi)中山大學(xué)青年教師培育項(xiàng)目（09lgpy14）：口服多肽類藥物的新型載體材料研究，2010.1-2012.12

(9) 廣東省教育部產(chǎn)學(xué)研結(jié)合項(xiàng)目（2012B091100457)：應(yīng)用智能靶向型納米粒包裹中藥糖視明緩釋新技術(shù)的研發(fā)，2012.12-2015.12

(10) 廣東省教育部產(chǎn)學(xué)研結(jié)合項(xiàng)目（2012B091100356)：研發(fā)高效、安全緩釋類風(fēng)濕關(guān)節(jié)炎藥物的原位水凝膠制劑，2012.06-2015.06

(11) 廣東省科技計(jì)劃項(xiàng)目(2009B020313001)：蝦、蟹殼聚糖的化學(xué)改性及其生物醫(yī)學(xué)納米材料的制備與應(yīng)用，2009.9-2012.8

(12) 廣東省教育部產(chǎn)學(xué)研結(jié)合項(xiàng)目（2009B090300122)：抗菌功能纖維及制品的研發(fā)，2009.1-2011.6

(1) Kunhua Lin, Juzhen Yi*, Xuhong Mao, Hao Wu, Li-Ming Zhang,Liqun Yang*. Glucose-sensitive hydrogels from covalently modified carboxylated pullulan and concanavalin A for smart controlled release of insulin.Reactive and Functional Polymers,2019,139,112-119.

(2) Shuyun Wu, Na Li, Chuan Yang, Li Yan, Xuan Liang, Meng Ren*,Liqun Yang*. Synthesis of cationic branched tea polysaccharide derivatives for targeted delivery of siRNA to hepatocytes.International Journal of Biological Macromolecules,2018,118,808-815.

(3) Jiayun Tan, Xiaojuan Wang, Zhong Yu, Jiahao Luo, Biyun Lan, Na Li, Yachuan Xin, Chunlian Zeng, Li Yan, Li-Ming Zhang, Xiaohong Chen, Shanyue Guan, Wei Li*,Liqun Yang*. Spectroscopic investigation of a hyperbranched cationic amylopectin derivative as a multi-guest molecular host for targeted delivery of a photosensitizer to pancreatic cancer cells.Carbohydrate Polymers,2018,197, 38-46.

(4) Jingnan Wang, Jiayun Tan, Jiahao Luo, Peilin Huang, Wuyi Zhou, Luming Chen, Lingli Long, Li-Ming Zhang, Banghao Zhu,Liqun Yang*, David YB Deng*. Enhancement of scutellarin oral delivery efficacy by vitamin B12-modified amphiphilic chitosan derivatives to treat type II diabetes induced-retinopathy.Journal of Nanobiotechnology.2017,15(18), 1u201317.

(5) Minghua Lai, Jingnan Wang, Jiayun Tan, Jiahao Luo, Li-Ming Zhang, David Y. B. Deng,*Liqun Yang*. Preparation, complexation mechanism and properties of nano-complexes ofAstragaluspolysaccharide and amphiphilic chitosan derivatives.Carbohydrate Polymers,2017,161, 261u2013269.

(6) Shuyun Wu, Minghua Lai, Jiahao Luo, Jingwen Pan, Li-Ming Zhang,Liqun Yang*. Interactions between α-amylase and an acidic branched polysaccharide from green tea.International Journal of Biological Macromolecules,2017,94, 669u2013678.

(7) Zhenzhen Liu, Haijun Gong, Rui Zeng, Xuan Liang, Li-Ming Zhang,Liqun Yang*, Yuqing Lan.* Efficient delivery of NF-КB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles.International Journal of Nanomedicine,2015,10, 2735-2749.

(8) Huajie Li, Zhong Yu, Shuangping Wang, Xi Long, Li-Ming Zhang, Zhaohua Zhu,Liqun Yang*. Photosensitizer-encapsulated amphiphilic chitosan derivative micelles: Photoactivity and enhancement of phototoxicity against human pancreatic cancer cells.Journal of Photochemistry and Photobiology B: Biology,2015,142, 212-219.

(9) Xuan Liang, Shuyun Wu, Xianyue Ren, Daping Quan, Li-Ming Zhang, Yubing Deng,Liqun Yang.*Complexation behaviors of hyperbranched cationic glycogen derivatives with plasmid DNA revealed by resonance light scattering and circular dichroism spectroscopy.Starch-Starke,2015,67, 838u2013845.

(10) Huajie Li, Zhong Yu, Shuangping Wang, Li-Ming Zhang,Liqun Yang*. Protection of photoactivity of photosensitizers by amphiphilic polysaccharide micelles.Chinese Journal of Polymer Science,2014,32, 1413u20131418.

(11) Zhong Yu, Huajie Li, Li-Ming Zhang, Zhaohua Zhu,Liqun Yang*. Enhancement of phototoxicity against human pancreatic cancer cells with photosensitizer-encapsulated amphiphilic sodium alginate derivative nanoparticles.International Journal of Pharmaceutics,2014,473, 501u2013509.

(12) Xuan Liang, Xianyue Ren, Zhenzhen Liu, Yingliang Liu, Jue Wang, Jingnan Wang, Li-Ming Zhang, David Y. B. Deng*, Daping Quan,Liqun Yang*. An efficient nonviral gene-delivery vector based on hyperbranched cationic glycogen derivatives.International Journal of Nanomedicine,2014,9, 419u2013435.

(13) Di Zeng, Jizhou Fan, Zhibin Deng, Jiayun Tan, Zheng Deng, Li-Ming Zhang,Liqun Yang*. One-step synthesis of amphiphilic hyperbranched amylopectin derivatives, characterization and use as functional nanovehicles.Carbohydrate Polymers,2013,98, 905u2013913.

(14)Liqun Yang*, Bifang Zhang, Juzhen Yi, Jiabao Liang, Yingliang Liu, Li-Ming Zhang. Preparation, characterization and properties of amylose-ibuprofen inclusion complexes.Starch-Starke,2013,65, 593u2013602.

(15) Yanfang Zhou, Bin Yang, Xianyue Ren, Zhenzhen Liu, Zheng Deng, Luming Chen, Yubin Deng*, Li-Ming Zhang,Liqun Yang*. Hyperbranched cationic amylopectin derivatives for gene delivery.Biomaterials,2012,33, 4731-4740.

(16) Huaisheng Zhou,Liqun Yang*, Huajie Li, Haijun Gong, Liangzheng Cheng, Haisheng Zheng, Li-Ming Zhang, Yuqing Lan*. Downregulation of VEGF mRNA expression by triamcinolone acetonide acetate-loaded chitosan derivative nanoparticles in human retinal pigment epithelial cells.International Journal of Nanomedicine,2012,7, 4649-4660.

(17)Liqun Yang*, Bin Yang, Di Zeng, Yu Wang, Li-Ming Zhang.Formation and property of a novel complex composed of amylose-grafted chitosan derivative and single-walled carbon nanotubes.Carbohydrate Polymers,2011,85, 845-853.

(18) Zhong Yu, Kaihong Huang, Wa Zhong, Wa Zhong,Liqun Yang, Qikui Chen, Zhaohua Zhu*. In vitro lethal effect of photodynamic therapy on human pancreatic cancer cells and its major influencing factors.Clinical Oncology Cancer Research,2011,8, 155u2013162.

(19) Xiaoai Chen, Lijun Zhang, Zhijie He, Wang, Weiwei , Bo Xu, Zhong Qian , Xintao Shuai,Liqun Yang, Yubin Deng*. Plasmid-encapsulated polyethylene glycol-grafted polyethylenimine nanoparticles for gene delivery into rat mesenchymal stem cells.International Journal of Nanomedicine,2011,6, 843u2013853.

(20)Liqun Yang*, Shanshan Fu, Xiane Zhu, Li-Ming Zhang, Yanrui Yang, Xiaomin Yang, Hui Liu. Hyperbranched acidic polysaccharide from green tea.Biomacromolecules,2010,11, 3395-3405.

(21)Liqun Yang*, Yuqing Lan*, Hui Guo, Liangzheng Cheng, Jizhou Fan, Xiang Cai, Li-Ming Zhang, Rufu Chen, Huaisheng Zhou. Ophthalmic drug-loadedN,O-carboxymethyl chitosan hydrogels: Synthesis, in vitro and in vivo evaluation.Acta Pharmacologica Sinica,2010,31, 1625-1634.

(22) Xiang Cai,Liqun Yang*, Li-Ming Zhang, Qing Wu. Evaluation of amylose used as a drug delivery carrier.Carbohydrate Research,2010,345, 922u2013928.

(23) Xiang Cai,Liqun Yang*, Li-Ming Zhang, Qing Wu. Synthesis and anaerobic biodegradation of indomethacin-conjugated cellulose ethers used for colon-specific drug delivery.Bioresource Technology,2009,100, 4164u20134170.

(24)Liqun Yang*, Li-Ming Zhang.Chemical structural and chain conformational characterization of some bioactive polysaccharides isolated from natural sources.Carbohydrate Polymers,2009,76, 349-361.(2017、2018年ESI高被引用論文)

(25)Liqun Yang*, Jianliang Kuang, Jun Wang, Zhiquan Li, Li-Ming Zhang.Loading and in vitro controlled release of indomethacin using amphiphilic cholesteryl-bearing carboxymethylcellulose derivatives,Macromolecular Bioscience,2008,8, 279-286.

(26)Liqun Yang*,Bifang Zhang, Yuting Liang, Bin Yang, Tao Kong,Li-Ming Zhang.In situ synthesis of amylose/single-walled carbon nanotubes supramolecular assembly,Carbohydrate Research,2008,343, 2463u20132467.

(27)Liqun Yang*,Jianliang Kuang, Zhiquan Li, Bifang Zhang, Xiang Cai, Li-Ming Zhang. Amphiphilic cholesteryl-bearing carboxymethylcellulose derivatives: self-assembly and rheological behaviour in aqueous solution,Cellulose,2008,15, 659-669.

(28)Liqun Yang*, Bifang Zhang, Liqun Wen, Qiuyi Liang, Li-Ming Zhang.Amphiphilic cholesteryl grafted sodium alginate derivative: Synthesis and self-assembly in aqueous solution,Carbohydrate Polymers,2007,68, 218-225.

(29)Liqun Yang*, Li-Ming Zhang, Ryouichi Ito and Youta Matsuo (Ed.). Handbook of Carbohydrate Polymers: Development, Properties and Applications: Chapter 24 u2013 Polysaccharides and Their Derivatives for Biomedical Applications, pp. 693-709. New York: Nova Science Publishers, Inc., 2010, ISBN: 978-1-60876-367-2.

(30) Xiang Cai,Liqun Yang*, Yifu Huang, Ningfu Peng, Li-Ming Zhang, Qing Wu, Rufu Chen. Targeted and controlled release of indomethacin from a prodrug of amylose,International Federation for Medical and Biological Engineering(IFMBE) Proceedings,2008,19, 29-31.

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