人物經(jīng)歷
1962年6月，謝曉亮出生于北京，并在北京大學(xué)附屬小學(xué)和北京大學(xué)附屬中學(xué)度過小學(xué)與中學(xué)階段。
1980年，考入北京大學(xué)化學(xué)系，業(yè)余時(shí)間還旁聽了物理系和數(shù)學(xué)系的課程，還利用暑假到實(shí)驗(yàn)室做實(shí)驗(yàn)，學(xué)有機(jī)合成，又寫計(jì)算機(jī)程序做化學(xué)計(jì)算。
1985年夏，赴加州大學(xué)圣地亞哥分校攻讀博士，師從研究超快激光研究化學(xué)動(dòng)力學(xué)的約翰·西蒙（John Simon）。
1989年，博士畢業(yè)后去芝加哥大學(xué)物理化學(xué)教授格雷厄姆·弗萊明（Graham Fleming）的實(shí)驗(yàn)室做博士后。
1992年，進(jìn)入美國(guó)太平洋西北國(guó)家實(shí)驗(yàn)室（PNNL）工作，從事單個(gè)分子光譜和動(dòng)力學(xué)、超高分辨光學(xué)成像研究，是PNNL自1965年成立以來第一位來自中國(guó)大陸的科學(xué)家。
1999年，被聘為哈佛大學(xué)化學(xué)與化學(xué)生物系終身教授，是改革開放以后哈佛大學(xué)引進(jìn)的第一位來自中國(guó)大陸的終身教授。
2000年，在哈佛大學(xué)的第一年，謝曉亮寫了6個(gè)申請(qǐng)書，全部獲得資助。
2001年9月7日，受聘北京大學(xué)化學(xué)學(xué)院客座教授，同一天，受聘為分子動(dòng)態(tài)與穩(wěn)態(tài)結(jié)構(gòu)國(guó)家重點(diǎn)實(shí)驗(yàn)室學(xué)術(shù)委員會(huì)委員。
2004年，獲得美國(guó)國(guó)立衛(wèi)生研究院（NIH）先鋒獎(jiǎng)，在之后五年中每年獲得50萬美元的自由支配經(jīng)費(fèi)。
2008年，被北京大學(xué)生命科學(xué)學(xué)院聘為講座教授。
2009年，擔(dān)任哈佛大學(xué)Mallinckrodt講席教授，是改革開放后大陸學(xué)者獲得哈佛大學(xué)冠名講席教授的第一人。
2010年12月，在北京大學(xué)主持創(chuàng)辦了北京大學(xué)生物動(dòng)態(tài)光學(xué)成像中心（BIOPIC），擔(dān)任主任。
2013年，第二次獲得美國(guó)國(guó)立衛(wèi)生研究院（NIH）先鋒獎(jiǎng)。
2015年，謝曉亮與斯坦福大學(xué)教授Karl Deisseroth共同獲得阿爾伯尼生物醫(yī)學(xué)獎(jiǎng)，成為該獎(jiǎng)項(xiàng)的首位華人獲得者；同年獲得美國(guó)化學(xué)會(huì)德拜獎(jiǎng)。
2016年，組建了北京未來基因診斷高精尖創(chuàng)新中心（ICG），擔(dān)任主任；10月17日，當(dāng)選為美國(guó)國(guó)家醫(yī)學(xué)院院士。
2017年9月16日，獲得求是杰出科學(xué)家獎(jiǎng)；11月，當(dāng)選中國(guó)科學(xué)院外籍院士。
2018年7月，正式全職回到北京大學(xué)工作，擔(dān)任北京大學(xué)李兆基講席教授；同年擔(dān)任主任的北京大學(xué)生物動(dòng)態(tài)光學(xué)成像中心，更名為“北京大學(xué)生物醫(yī)學(xué)前沿創(chuàng)新中心”（Biomedical Pioneering Innovation Center，BIOPIC）。
2019年11月，擔(dān)任北京大學(xué)理學(xué)部主任。
主要成就
科研成就
科研綜述謝曉亮是單分子酶學(xué)的創(chuàng)始人、單分子生物物理化學(xué)的奠基人之一、相干拉曼散射顯微成像技術(shù)和單細(xì)胞基因組學(xué)的開拓者。謝曉亮教授作為單分子生物物理化學(xué)家，他勇于突破學(xué)科界限，從物理化學(xué)、生物物理到生物化學(xué)，再到分子生物學(xué)、基因組學(xué)及臨床醫(yī)學(xué)，無畏探索，不斷創(chuàng)新，在相關(guān)新興交叉學(xué)科做出了創(chuàng)造性貢獻(xiàn)。
謝曉亮不僅是生物物理化學(xué)基礎(chǔ)科學(xué)研究的國(guó)際領(lǐng)軍人物，近年來大力推動(dòng)了無標(biāo)記光學(xué)成像技術(shù)和新型單細(xì)胞基因組測(cè)序技術(shù)在醫(yī)學(xué)中的應(yīng)用。2012年謝曉亮在單細(xì)胞全基因組學(xué)研究有了突破性進(jìn)展，開發(fā)了單細(xì)胞全基因組均勻擴(kuò)增的新方法—多重退火循環(huán)擴(kuò)增法（MALBAC）。2014年9月19日，世界上第一例“MALBAC嬰兒”在北醫(yī)三院誕生，標(biāo)志著中國(guó)胚胎植入前遺傳診斷技術(shù)處于世界領(lǐng)先水平。迄今為止，謝曉亮團(tuán)隊(duì)利用MALBAC技術(shù)為中國(guó)三百多個(gè)患有單基因遺傳病的家庭成功避免了疾病的子代傳遞，為數(shù)千位孕婦避免了染色體異常胚胎的移植，減少了流產(chǎn)和唐氏綜合征等染色體異常疾病的發(fā)生。
研究領(lǐng)域謝曉亮課題組的研究方向包含基礎(chǔ)科學(xué)研究領(lǐng)域、技術(shù)研究領(lǐng)域和醫(yī)學(xué)研究領(lǐng)域三個(gè)領(lǐng)域。
基礎(chǔ)研究：?jiǎn)畏肿用笇W(xué)、單分子生物物理化學(xué)、基因表達(dá)和調(diào)控、表觀遺傳學(xué)、細(xì)胞分化和重編程機(jī)理、基因組不穩(wěn)定性；
技術(shù)發(fā)展：?jiǎn)畏肿映上�、單�?xì)胞基因組學(xué)、相干拉曼散射顯微成像、DNA 測(cè)序；
醫(yī)學(xué)研究：體外受精胚胎植入前遺傳學(xué)篩查與診斷、早期癌癥診斷。
學(xué)術(shù)論著截至2017年4月，謝曉亮教授共發(fā)表SCI收錄科學(xué)論文210余篇。
Single Molecule Spectroscopy and Imaging
Xie, X. Sunney; Dunn, Robert C. "Probing Single Molecule Dynamics" Science 265: 361-364 (1994).
Sánchez, Erik J; Novotny, Lukas; Xie, X. Sunney. "Near-field Fluorescence Microscopy Based on Two-photon Excitation with Metal Tips" Phys Rev Lett 82: 4014-4017 (1999).
Min, Wei; Lu, Sijia; Chong, Shasha; Roy, Rahul; Holtom, Gary R.; Xie, X. Sunney. "Imaging Chromophores with Undetectable Fluorescence by Stimulated Emission Microscopy" Nature 461: 1105-1109 (2009).
Chong, Shasha; Min, Wei; Xie, X. Sunney. "Ground-State Depletion Microscopy: Detection Sensitivity of Single-Molecule Optical Absorption at Room Temperature" J Phys Chem Lett 1:3316-3322 (2010).
Zhou, Yuexin; Wang, Ping; Tang, Feng; Gao, Ge; Huang, Lei; Wei, Wensheng; Xie, X. Sunney “Painting a specific chromosome with CRISPR/Cas9 for live-cell imaging”, Cell Research, doi:10.1038/cr.2017.9 (2017).
Single Molecule Enzymology
Lu, H. Peter; Xun, Luying; Xie, X. Sunney. "Single-Molecule Enzymatic Dynamics" Science 282: 1877-1882 (1998).
Yang, Haw; Luo, Guobin; Karnchanaphanurach, Pallop; Louie, Tai-Man; Rech, Ivan; Cova, Sergio; Xun, Luying; Xie, X. Sunney. "Protein Conformational Dynamics Probed by Single-Molecule Electron Transfer" Science 302: 262-266 (2003).
Min, Wei; Luo, Guobin; Cherayil, Binny J.; Kou, S. C.; Xie, X. Sunney. "Observation of a Power-Law Memory Kernel for Fluctuations within a Single Protein Molecule" Phys Rev Lett 94: 198302(1-4) (2005).
English, Brian P.; Min, Wei; van Oijen, Antoine M.; Lee, Kang Taek; Luo, Guobin; Sun, Hongye; Cherayil, Binny J.; Kou, S.C.; Xie, X. Sunney. "Ever-Fluctuating Single Enzyme Molecules: Michaelis-Menten Equation Revisited" Nat Chem Bio 2: 87-94 (2006).
Blainey, Paul C.; Luo, Guobin; Ko9u, S.C.; Mangel, Walter F.; Verdine, Gregory L.; Bagchi, Biman; Xie, X. Sunney. "Nonspecifically Bound Proteins Spin While Diffusing Along DNA" Nat Struct Mol Biol 16: 1224-1229 (2009).
Kim, Sangjin; Brostr?mer, Erik, Xing, Dong; Jin, Jianshi; Chong, Shasha; Ge, Hao, Wang, Siyuan; Gu, Chan; Yang, Lijiang; Gao, Yiqin; Su, Xiao-dong; Sun, Yujie; Xie, X. Sunney. “Probing Allostery Through DNA” Science 339: 816-819 (2013).
Chong, Shasha; Chen, Chongyi; Ge, Hao; Xie, X. Sunney. "Mechanism of Transcriptional Bursting in Bacteria" Cell 158: 314-326 (2014).
Gene Expression and Regulation
Yu, Ji; Xiao, Jie; Ren, Xiaojia; Lao, Kaiqin; Xie, X. Sunney. "Probing Gene Expression in Live Cells, One Protein Molecule at a Time" Science 311: 1600-1603 (2006).
Cai, Long; Friedman, Nir; Xie, X. Sunney. "Stochastic Protein Expression in Individual Cells at the Single Molecule Level" Nature 440: 358-362 (2006).
Elf, Johan; Li, Gene-Wei; Xie, X. Sunney. "Probing Transcription Factor Dynamics at the Single-Molecule Level in a Living Cell" Science 316: 1191-1194 (2007).
Choi, Paul J.; Cai, Long; Frieda, Kirsten; Xie, X. Sunney. "A Stochastic Single-Molecule Event Triggers Phenotype Switching of a Bacterial Cell" Science 322: 442-446 (2008).
Taniguchi, Yuichi; Choi, Paul J.; Li, Gene-Wei; Chen, Huiyi; Babu, Mohan; Hearn, Jeremy; Emili, Andrew; Xie, X. Sunney. "Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells" Science 329: 533-538 (2010).
Chong, Shasha; Chen, Chongyi; Ge, Hao; Xie, X. Sunney. "Mechanism of Transcriptional Bursting in Bacteria" Cell 158: 314-326 (2014).
Ge, Hao; Qian, Hong; and Xie, X. Sunney. "Stochastic Phenotype Transition of a Single Cell in an Intermediate Region of Gene State Switching" Phys Rev Lett 114(7) (2015).
Coherent Raman Microscopy
Zumbusch, Andreas; Holtom, Gary R.; Xie, X. Sunney. “Vibrational Microscopy Using Coherent Anti-Stokes Raman Scattering" Phys Rev Lett 82: 4142-4145 (1999).
Evans, Conor L.; Potma, Eric O.; Puoris'haag, Mehron; C?té, Daniel; Lin, Charles P.; Xie, X. Sunney. "Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy" Proc Nat. Aca Sci 102: 16807-16812 (2005).
Freudiger, Christian W.; Min, Wei; Saar, Brian G.; Lu, Sijia; Holtom, Gary R.; He, Chengwei; Tsai, Jason C.; Kang, Jing X.; Xie, X. Sunney. "Label-Free Biomedical Imaging with High sensitivity by Stimulated Raman Scattering Microscopy" Science 322:1857-1860 (2008).
Saar, Brian G.; Freudiger, Christian W.; Reichman, Jay; Stanley, C. Michael; Holtom, Gary R.; Xie, X. Sunney. "Video-Rate Molecular Imaging in Vivo with Stimulated Raman Scattering" Science 330: 1368-1370 (2010).
Wang, Meng C.; Min, Wei; Freudiger, Christian W.; Ruvkun, Gary; Xie, X. Sunney. "RNAi Screening for Fat Regulatory Genes with SRS Microscopy" Nat Methods 8: 135-138 (2011).
Fu, Dan; Zhou, Jing; Zhu, Wenjing Suzanne; Manley, Paul W.; Wang, Y. Karen; Hood, Tami; Wylie, Andrew; Xie, X. Sunney. "Imaging the Intracellular Distribution of Tyrosine Kinase Inhibitors in Living Cells with Quantitative Hyperspectral Stimulated Raman Scattering" Nat Chem 6: 614-622 (2014).
Single Cell Genomics
Zong, Chenghang; Lu, Sijia; Chapman, Alec R.; Xie, X. Sunney. "Genome-Wide Detection of Single-Nucleotide and Copy-Number Variations of a Single Human Cell" Science 338: 1622-1626 (2012).
Lu, Sijia; Zong, Chenghang; Fan, Wei; Yang, Mingyu; Li, Jinsen; Chapman, Alec R.; Zhu, Ping; Hu, Xuesong; Xu, Liya; Bai, Fan; Qiao, Jie; Tang, Fuchou; Li, Ruiqiang; Xie, X. Sunney. "Probing Meiotic Recombination and Aneuploidy of Single Sperm Cells by Whole-Genome Sequencing" Science 338: 1627-1630 (2012).
Hou, Yu; Fan, Wei; Yan, Liying; Li, Rong; Lian, Ying; Huang, Jin; Li, Jinsen; Xu, Liya; Tang, Fuchou; Xie, X. Sunney; Qiao, Jie. "Genome Analyses of Single Human Oocytes" Cell 155: 1492-1506 (2013).
Yan, Liying; Huang, Lei; Xu, Liya; Huang, Jin; Ma, Fei; Zhu, Xiaohui; Tang, Yaqiong; Liu, Mingshan; Lian, Ying; Liu, Ping; Li, Rong; Lu, Sijia; Tang, Fuchou; Qiao, Jie; Xie, X Sunney "Live Births after Simultaneous Avoidance of Monogenic Diseases and Chromosome Abnormality by Next-generation Sequencing with Linkage Analyses," Proc Natl Acad Sci USA, 112(52), 15964-15969, (2015).
Chen, Chongyi; Xing, Dong; Tan, Longzhi; Li, Heng; Zhou, Guangyu; Huang, Lei; Xie, X. Sunney "Single-cell whole-genome analyses by Linear Amplification via Transposon Insertion (LIANTI)," Science 356, 189-194 (2017).
Key Review Articles
Min, Wei; Freudiger, Christian W.; Lu, Sijia; Xie, X. Sunney. "Coherent Nonlinear Optical Imaging: beyond Fluorescence Microscopy" Annu. Rev. Phys. Chem. 62: 507-530 (2011).
Li, Gene-Wei; Xie, X. Sunney. "Central Dogma at the Single-Molecule Level in Living Cells" Nature 475: 308-315 (2011).
Xie, X. Sunney. "Enzyme Kinetics, Past and Present" Science 342: 1457-1459 (2013).
Xie, X. Sunney. "Single Molecules Meet Genomics: Pinpointing Precision Medicine" JAMA 20: 2021-2 (2015).
Huang Lei; Ma Fei; Chapman Alec; Lu Sijia; Xie X. Sunney. “Single-Cell Whole-Genome Amplification and Sequencing” Annu. Rev. Genomics Hum. Genet. 16: 79-102 (2015).
Cheng, Ji-xin; Xie, X. Sunney. “Vibrational Spectroscopic Imaging of Living Systems: An Emerging Platform for Biology and Medicine” Science 350, aaa8870 (2015).
人才培養(yǎng)
1999年，謝曉亮進(jìn)入哈佛大學(xué)任教來，培養(yǎng)了多名博士和博士后，截止到2017年，他所培養(yǎng)的學(xué)生在世界四十多所大學(xué)任教，其中一些學(xué)生的具體信息如下：
| Graduate Students | ||
| Srinjan Basu | 2006-2012 | Cambridge University |
| Paul Blainey | 2001-2007 | Assistant Professor, Department of Biological Engineering, MIT, Broad Institute |
| Long Cai | 2001-2006 | Assistant Professor of Chemistry, CalTech |
| Chongyi Chen | 2009-2014 | Harvard Univerisity, Cambridge, Massachusetts |
| Huiyi Chen | 2006-2011 | Nanyang Technological Univerisity, Lee Kong Chian School of Medicine, Singapore |
| Paul J. Choi | 2005-2009 | Senior Research Scientist , Genome Institute of Singapore |
| Shasha Chong | 2009-2014 | Department of Molecular & Cell Biology, University of California, Berkeley, California |
| Brian English | 2001-2007 | Albert Einstein College of Medicine |
| Conor Evans | 2002-2007 | Assistant Professor, Harvard Medical School |
| Christian Freudiger | 2007-2011 | CTO and Cofounder, Invenio Imaging |
| Sangjin Kim | 2004-2010 | Department of Molecular, Cellular & Developmental Biology, Yale University |
| John Krug | 1998-2004 | Roche |
| Gene-Wei Li | 2005-2010 | University of California, San Francisco |
| Sijia Lu | 2008-2012 | CTO and Cofounder, Yikon Genomics, Taizhou, China |
| Guobin Luo | 2000-2006 | Life Technologies |
| Wei Min | 2001-2007 | Assistant Professor, Columbia University |
| Xiaolin Nan | 2001-2007 | Assistant Professor, Oregon Health Science University |
| Brian Saar | 2005-2010 | Lincoln Laboratory, Massachusetts Institute of Technology |
| ErikSánchez | 1995-1999 | Assistant Professor, Portland State University |
| Peter Sims | 2005-2009 | Assistant Professor of Systems Biology, Department of Biochemistry & Molecular Physics, Columbia University Medical Center |
| Zi Hertz He | 2011-2014 | Bloomberg L.P., London |
| Ziqing Winston Zhao | 2009-2015 | Postdoc, Institute for Molecular and Cell Biology (IMCB), Singapore |
| Xu Zhang | 2010-2015 | Postdoctoral Fellow, Harvard University |
| Wenlong Yang | 2011-2017 | Postdoctoral Fellow, Harvard University |
| Postdoctoral Fellows | ||
| Dr. David Arnett | 1998-1999 | Associate Professor, Northwestern College, Iowa |
| Dr. Lewis Book | 2000-2001 | Northrop Grumman Space Technology, California |
| Dr. Erik Brostromer | 2010-2011 | |
| Dr. Silvia Carrasco | 2005-2006 | Knowledge and Technology Transfer (KTT) director, ICFO |
| Dr. Huiyi Chen | 2011-2012 | Nanyang Technological Univerisity, Lee Kong Chian School of Medicine, Singapore |
| Dr. Peng Chen | 2004-2005 | Peter Debye Professor of Chemistry, Cornell University, Deptartment of Chemistry and Chemical Biology |
| Dr. Ji-Xin Cheng | 2000-2003 | Professor, Purdue University, Weldon School of Biomedical Engineering |
| Dr. James Chesko | 1997 | Novartis Vaccines and Diagnostics, Emeryville, California |
| Dr. Jonathan Choi | 1999-2000 | |
| Dr. Paul J. Choi | 2009-2010 | Senior Research Scientist , Genome Institute of Singapore |
| Dr. Robert A. Crowell | 1994-1995 | Brookhaven National Laboratory |
| Dr. Haifeng Duan | 2009-2011 | Biodynamic Optical Imaging Center (BIOPIC), Peking University, China |
| Dr. Xiaojie Duan | 2007-2008 | Assistant Professor, Peking University |
| Dr. Robert C. Dunn | 1992-1995 | Professor of Chemistry, University of Kansas |
| Dr. Johan Elf | 2005-2007 | Associate Professor in Molecular Biotechnology, University of Uppsala, Sweden |
| Dr. Wagner Faustino | 2008-2010 | Adjunct Professor, Federal University of Paraiba, Brazil |
| Dr. Kevin Fiala | 2007-2009 | MIT, Office of Technology Development |
| Dr. Christian Freudiger | 2011-2013 | CTO and Cofounder, Invenio Imaging |
| Dr. Nir Friedman | 2003-2007 | Weizmann Institute, Israel |
| Dr. Marcel Friedrich | 2007-2008 | Siemens Management Consulting, Munich, Germany |
| Dr. Feruz Ganikhanov | 2004-2006 | Assistant Professor, West Virginia University |
| Dr. Christof Gebhardt | 2010-2013 | Deputy Head, Institute of Biophysics, Ulm University, Germany |
| Dr. William Greenleaf | 2008-2011 | Assistant Professor, Genetics Dept., Stanford University School of Medicine |
| Dr. Terumasa Ito | 2011-2012 | Sony Coporation Research & Development |
| Dr. Minbiao Ji | 2011-2014 | Professor, Department of Physics, Fudan University, Shanghai, China |
| Dr. Lingjie Kong | 2012-2013 | Janelia Farm Research Campus, Virginia |
| Dr. Kang Taek Lee | 2003-2004 | Assistant Professor, Department of Chemistry, Gwangju Institute of Science and Technology (GIST), Korea |
| Dr. Nam Ki Lee | 2006-2009 | Assistant Professor, Pohang University of Science and Technology, S. Korea |
| Dr. Gene-Wei Li | 2010 | UCSF |
| Dr. Jeff Li | 2002-2008 | Massachusetts Institute of Technology |
| Dr. Giuseppe Lia | 2006-2009 | CNRS, Centre de Genetique Moleculaire, Paris |
| Dr. Hong Peter Lu | 1995-1999 | Professor, Ohio Eminent Scholar, Bowling Green State University |
| Dr. Guobin Luo | 2006-2008 | Life Technologies |
| Dr. Yuntao Steve Mao | 2011-2012 | Scientific Editor, Cell, Cell Press, Cambridge |
| Dr. Wei Min | 2008-2010 | Assistant Professor, Columbia University, Department of Chemistry |
| Dr. Lukas Novotny | 1996-1999 | Professor, ETH Zürich |
| Dr. Antoine van Oijen | 2001-2004 | Professor, University of Wollongong, Australia |
| Dr. Pavel Pospisil | 2001-2002 | Palacky University, Czech Republic, Department of Experimental Physics |
| Dr. Eric Potma | 2001-2005 | Associate Professor, University of California at Irvine, Department of Chemistry |
| Dr. Maarten Roeffaers | 2009-2010 | Assistant Professor, Katholieke Universiteit Leuven |
| Dr. Rahul Roy | 2007-2012 | Assistant Professor, Indian Institute of Science, Department of Chemical Engineering, Bangalore, India |
| Dr. Markus Rueckel | 2007-2008 | BASF, Germany |
| Dr. Erik Sánchez | 1999-2002 | Assistant Professor of Physics, Portland State University |
| Dr. Ahbijit Sarkar | 2002-2003 | Assistant Professor, Dept. of Chemistry & Physics, Virginia State University |
| Dr. Charles Schroeder | 2004-2007 | Assistant Professor, University of Illinois, Urbana-Champaign, Department of Biomolecular Engineering |
| Dr. Katsuyuki Shiroguchi | 2009-2012 | Laboratory Leader, RIKEN Research Center for Allergy & Immunology, Laboratory for Integrative Genomics |
| Dr. Peter Sims | 2009-2011 | Assistant Professor of Systems Biology, Department of Biochemistry & Molecular Physics, Columbia University Medical Center |
| Dr. Hongye Sun | 2000-2002 | Vice President of Operation and Technology Platform, Chief Operating Officer, WuXi Genomic Center, WuXi AppTec, Shanghai |
| Dr. David Suter | 2011-2013 | Assistant Professor, School of Life Sciences, EPFL, Switzerland |
| Dr. Yuichi Taniguchi | 2006-2011 | Unit Leader, Quantitative Biology Center, RIKEN, Japan |
| Dr. Andreas Volkmer | 1999-2001 | University of Stuttgart, Germany, Institute of Physics |
| Dr. David Ward | 2005-2007 | President and Chairman, Piffany, Inc. |
| Dr. Jie Xiao | 2002-2006 | Assistant Professor, Johns Hopkins University School of Medicine, Department of Biophysics and Biophysical Chemistry |
| Dr. Haw Yang | 2000-2002 | Associate Professor of Chemistry, Princeton University |
| Dr. Wei Yuan Yang | 2005-2007 | Researcher, Academia Sinica, Taiwan, Institute of Biological Chemistry |
| Dr. Jun Yong | 2011-2013 | Biodynamic Optical Imaging Center (BIOPIC), Peking University, China |
| Dr. Ji Yu | 2002-2006 | Assistant Professor of Genetics and Developmental Biology, University of Connecticut Health Center |
| Dr. Guoqing Zhang | 2010-2011 | Assistant Professor, University of Science and Technology of China, School of Chemistry and Materials Science |
| Dr. Chenghang Zong | 2009-2013 | Assistant Professor, Department of Molecular and Human Genetics. Baylor College of Medicine |
| Dr. Andreas Zumbusch | 1997-1999 | Professor of Physical Chemistry, Universit?t Konstanz, Germany |
| Dr. Yan Gu | 2013-2014 | Scientist at Bristol-Myers Squibb |
| Dr. Dan Fu | 2010-2015 | Assistant Professor, Department of Chemistry, University of Washington |
| Dr. Xiaohui Ni | 2011-2015 | Cynvenio Biosystems, California |
| Dr. Yi Yin | 2015-2016 | Postdoc, University of Washington |
| Dr. Haisong Liu | 2014-2016 | Postdoctoral Fellow, Salk Institute |
| Dr. Asaf Tal | 2015-2017 | |
| Dr. Fa-Ke Frank Lu | 2011-2017 | Assistant Professor, Department of Biomedical Engineering, Binghamton University, State University of New York |
| Dr. Sabin Mulepati | 2014-2017 | Intellia Therapeutics, Massachusetts |
| Visiting Scholars | ||
| Prof. Jianming Li | 2011 | Southern Medical University, China |
| Prof. Biman Bagchi | 2007 | Indian Institute of Science |
| Prof. Paul Champion | 2002-2003 | Department of Physics, Northeastern University |
| Prof. Binny Cherayil | 2004-2005 | Department of Inorganic and Physical Chemistry, Indian Institute of Science |
| Prof. Nai-Ho Cheung | 2000-2001 | Department of Physics, Hong Kong Baptist University |
| Dr. Peijun Cong | 2010 | Invenio Imaging |
| Dr. Mircea Cotlet | 2003 | Brookhaven National Laboratory, Center for Functional Nanomaterials |
| Prof. Hao Ge | 2010-2011 | Biodynamic Optical Imaging Center (BIOPIC), Peking University, China |
| Prof. Casey Hynes | 2011 | Department of Molecular Biophysics, University of Colorado, Boulder |
| Prof. Carey Johnson | 1997 | Department of Chemistry, University of Kansas |
| Dr. Laura Kaufman | 2002-2004 | Department of Chemistry, Columbia University |
| Dr. Francois Legare | 2004-2006 | INRS-EMT, Université du Québec, Varennes, Canada |
| Prof. Peter Leung | 1995 | Department of Physics, Portland State University |
| Prof. Yuanzong Li | 2002-2003 | College of Chemistry and Molecular Engineering, Peking University, China |
| Prof. Vahid Sandoghdar | 2009 | Department of Chemistry, Swiss Federal Institute of Technology, Switzerland |
| Prof. Andrei Tokmakoff | 2005-2006 | Department of Chemistry, Massachusetts Institute of Technology |
| Dr. Martin Vogel | 2006-2008 | Max Planck Institute of Biophysics, Department of Molecular Neurogenetics |
| Prof. Nils Walter | 2006 | Department of Chemistry, University of Michigan |
| Prof. Xinhua Wan | 2004-2005 | College of Chemistry and Molecular Engineering, Peking University, China |
| Prof. Peng-Ye Wang | 2010 | Institute of Physics, Chinese Academy of Sciences |
| Prof. Luying Xun | 2004-2005 | School of Molecular Biosciences, Washington State University |
| Prof. Xinsheng Zhao | 2003 | College of Chemistry and Molecular Engineering, Peking University, China |
| Prof. Zemin Yao | 2014-2015 | Department of Biochemistry, Microbiology, and Immunology, University of Ottawa, Canada |
| Yuanzhen Suo | 2015-2017 | Shanghai Jiao Tong University |
| Shufang Wang | 2016-2017 | Chinese PLA General Hospital |
榮譽(yù)表彰
| 時(shí)間 | 獎(jiǎng)項(xiàng)/榮譽(yù) | 授予單位 |
|---|---|---|
| 2017年12月 | 2017年度中國(guó)留學(xué)人員50人榜單 | |
| 2017年11月 | 中國(guó)科學(xué)院外籍院士 | 中國(guó)科學(xué)院 |
| 2017年9月 | 求是杰出科學(xué)家獎(jiǎng) | 香港求是基金會(huì) |
| 2016年10月 | 美國(guó)國(guó)家醫(yī)學(xué)院院士 | 美國(guó)國(guó)家醫(yī)學(xué)院 |
| 2016年 | 吳瑞獎(jiǎng) | 華人生物學(xué)家協(xié)會(huì) |
| 2015年 | 貝時(shí)璋獎(jiǎng) | 中國(guó)生物物理學(xué)會(huì) |
| 2015年 | 阿爾伯尼生物醫(yī)學(xué)獎(jiǎng)（Albany） | 紐約州阿爾巴尼醫(yī)學(xué)中心 |
| 2015年 | Peter Debye物理化學(xué)獎(jiǎng) | 美國(guó)化學(xué)會(huì) |
| 2014年 | 美國(guó)光學(xué)會(huì)會(huì)士 | 美國(guó)光學(xué)會(huì) |
| 2014年 | 德國(guó)洪堡學(xué)者 | |
| 2013年 | 美國(guó)NIH Director's Pioneer Award | |
| 2013年 | Ellis R. Lippincott獎(jiǎng) | 美國(guó)光學(xué)學(xué)會(huì)及應(yīng)用光譜學(xué)會(huì) |
| 2012年 | Harrison Howe獎(jiǎng) | 美國(guó)化學(xué)會(huì)Rochester分部 |
| 2012年 | 美國(guó)微生物學(xué)會(huì)會(huì)士 | 美國(guó)微生物學(xué)會(huì) |
| 2012年 | Founders獎(jiǎng) | 美國(guó)生物物理學(xué)會(huì) |
| 2011年5月3日 | 美國(guó)國(guó)家科學(xué)院院士 | 美國(guó)國(guó)家科學(xué)院 |
| 2010年 | 中國(guó)化學(xué)會(huì)榮譽(yù)會(huì)士 | 中國(guó)化學(xué)會(huì) |
| 2009年 | 歐內(nèi)斯特·奧蘭多·勞倫斯獎(jiǎng)（化學(xué)類） | 美國(guó)能源部 |
| 2008年 | 美國(guó)物理學(xué)會(huì)會(huì)士 | 美國(guó)物理學(xué)會(huì) |
| 2008年 | 美國(guó)藝術(shù)與科學(xué)學(xué)院院士 | 美國(guó)藝術(shù)與科學(xué)學(xué)院 |
| 2008年 | Berthold Leibinger Zukunftspreis激光技術(shù)獎(jiǎng) | |
| 2007年 | Willis E.Lamb激光科學(xué)與量子光學(xué)獎(jiǎng) | |
| 2006年 | 美國(guó)科學(xué)促進(jìn)會(huì)會(huì)士 | 美國(guó)科學(xué)促進(jìn)會(huì) |
| 2006年 | 美國(guó)生物物理學(xué)會(huì)會(huì)士 | 美國(guó)生物物理學(xué)會(huì) |
| 2004年 | 美國(guó)NIH Director's Pioneer Award | |
| 2003年 | 以色列Raymond and Beverly Sackler 物理科學(xué)獎(jiǎng) | |
| 2003年 | Hoope獎(jiǎng) | 哈佛大學(xué) |
| 2003年 | Joe Markson優(yōu)秀本科畢業(yè)論文指導(dǎo)教師 | |
| 1996年 | Coblentz獎(jiǎng) |
社會(huì)任職
| 任職時(shí)間 | 擔(dān)任職務(wù) |
|---|---|
| 2009年—2011年 | 《Science》編委 |
| 2004年— | 國(guó)家納米科學(xué)中心學(xué)術(shù)委員會(huì)委員（第一屆、第二屆） |
| 2002年—2007年 | 《Ann. Rev. Phys. Chem.》編委 |
| 2001年—2006年 | 《Acc. Chem. Res.》編委 |
| 2001年—2009年 | 中國(guó)科學(xué)院化學(xué)研究所分子動(dòng)態(tài)與穩(wěn)態(tài)結(jié)構(gòu)國(guó)家重點(diǎn)實(shí)驗(yàn)室學(xué)術(shù)委員會(huì)委員（第五屆） |
| 2001年— | 《Chem. Phys.》編委 |
| 2001年— | 《Chem. Phys. Lett.》編委 |
| 2000年— | 《Chem. Phys. Chem.》編委 |
| 2000年—2008年 | 《J. Phys. Chem.》編委 |
| 1999年—2007年 | 《J. Microscopy》編委 |
| 1999年—2002年 | 《Single Molecules》編委 |
| 2000年—2001年 | 《Biophysical J.》編委 |
| 《物理化學(xué)學(xué)報(bào)》編委 |
個(gè)人生活
家世背景謝曉亮的父親謝有暢與母親楊駿英皆為北京大學(xué)化學(xué)系的教授。
人物評(píng)價(jià)
謝曉亮在非線性拉曼顯微學(xué)和高靈敏度分子振動(dòng)成像領(lǐng)域具有創(chuàng)新研究，在創(chuàng)立單分子生物物理化學(xué)領(lǐng)域中處于科學(xué)領(lǐng)導(dǎo)地位，而且他在酶反應(yīng)動(dòng)力學(xué)和活細(xì)胞基因表達(dá)領(lǐng)域做出了杰出工作。（2009年美國(guó)歐內(nèi)斯特·奧蘭多·勞倫斯獎(jiǎng)）
謝曉亮是單細(xì)胞生物學(xué)領(lǐng)域的領(lǐng)軍人物，他已在該領(lǐng)域做出了關(guān)于單個(gè)分子及其行為影響細(xì)胞的生命過程乃至人類疾病的諸多研究成果。（2015年美國(guó)阿爾伯尼生物醫(yī)學(xué)獎(jiǎng)）
謝曉亮是學(xué)科交叉研究的踐行者，從物理化學(xué)、生物物理到生物化學(xué)，再到分子生物學(xué)，基因組學(xué)及臨床醫(yī)學(xué)，他無畏探索，不斷創(chuàng)新，他是單分子酶學(xué)的創(chuàng)始人、單分子生物物理化學(xué)的奠基人之一、相干拉曼散射顯微成像技術(shù)和單細(xì)胞基因組學(xué)的開拓者，在單分子生物物理和生物醫(yī)學(xué)光學(xué)成像領(lǐng)域作出了杰出的貢獻(xiàn)。（2017年求是科學(xué)基金會(huì)評(píng)）
做事情就是要持之以恒，不要放棄，要堅(jiān)持，要不怕困難的做下去，要有耐心，不要追求那種短期就能出成果的東西。謝曉亮常常會(huì)用4年甚至更長(zhǎng)的時(shí)間來做一個(gè)研究，他發(fā)現(xiàn)自己做錯(cuò)的東西，也不放棄，重新開始做，所以，堅(jiān)持是一個(gè)很重要的東西，是他獲得成功肯定的一個(gè)很重要的元素，對(duì)我也意義重大。（美國(guó)國(guó)家科學(xué)院院士、哈佛大學(xué)教授莊小威）
謝曉亮的第一個(gè)基礎(chǔ)研究工作是1998年開展的單分子酶學(xué)，他開創(chuàng)了在單分子層面對(duì)生命過程的研究。近年他又開始探探索在醫(yī)學(xué)上的應(yīng)用。中國(guó)引進(jìn)現(xiàn)代醫(yī)學(xué)后，在現(xiàn)代藥學(xué)方面只有少數(shù)幾個(gè)藥物作用領(lǐng)域的發(fā)現(xiàn)，在現(xiàn)代醫(yī)學(xué)技術(shù)上唯一的發(fā)明和應(yīng)用就是謝曉亮和湯富酬、喬杰三個(gè)團(tuán)隊(duì)合作誕生的u2018MALBAC嬰兒u2019。（北京大學(xué)生命科學(xué)院饒毅）
謝曉亮的MALBAC技術(shù)能夠改變整個(gè)生物醫(yī)學(xué)，其對(duì)未來精準(zhǔn)醫(yī)學(xué)的發(fā)展和應(yīng)用的貢獻(xiàn)是不可限量的。“獲得終身教授的人很多，但真正能夠在人類歷史上，特別是科技史上留下印記的科學(xué)家非常少見，而謝曉亮將理論和技術(shù)結(jié)合，用技術(shù)解決科學(xué)問題，是引領(lǐng)整個(gè)科學(xué)界發(fā)展的真正的一流科學(xué)家，他是一個(gè)讓你無法預(yù)知將來還會(huì)做出什么創(chuàng)造性工作的科學(xué)家。這是一個(gè)科學(xué)家具有潛在創(chuàng)造力、影響力、引領(lǐng)力的標(biāo)志。（中國(guó)醫(yī)學(xué)科學(xué)院院長(zhǎng)曹雪濤）
